SCN5A Antikörper (AA 1021-1034)

Produktnummer ABIN1104138

Produktdetails anti-SCN5A Antikörper

Target: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Bindungsspezifität: AA 1021-1034

Reaktivität: Human, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SCN5A Antikörper ist unkonjugiert

Applikation: ELISA

Spezifität: Human SCN5A / Nav1.5. This antibody is expected to recognize all reported isoforms (NP_932173.1, NP_000326.2, NP_001092874.1, NP_001092875.1, NP_001153632.1, NP_001153633.1).

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%) Marmoset (86%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-PTRKETRFEEGEQP from an internal region of human SCN5A / Nav1.5 (NP_932173.1, NP_000326.2, NP_001092874.1, NP_001092875.1, NP_001153632.1, NP_001153633.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%), Marmoset (86%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: Peptide-ELISA (1:16000)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Preliminary experiments gave an approx 80kD band in HeLa lysates after 0.3 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 227kD according to NP_932173.1. The 80kD band was successfully blocked by incubation with the immunizing peptide.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu SCN5A

Target: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Andere Bezeichnung: SCN5A / Nav1.5 (SCN5A Produkte)

Synonyme: Nav1.5 antikoerper, Nav1.5c antikoerper, SkM1 antikoerper, SkM2 antikoerper, mH1 antikoerper, CDCD2 antikoerper, CMD1E antikoerper, CMPD2 antikoerper, HB1 antikoerper, HB2 antikoerper, HBBD antikoerper, HH1 antikoerper, ICCD antikoerper, IVF antikoerper, LQT3 antikoerper, PFHB1 antikoerper, SSS1 antikoerper, VF1 antikoerper, SCAL antikoerper, sodium voltage-gated channel alpha subunit 5 antikoerper, sodium channel, voltage-gated, type V, alpha antikoerper, SCN5A antikoerper, Scn5a antikoerper

Hintergrund: Name/Gene ID: SCN5A
Subfamily: Sodium channel - voltage-gated
Family: Ion Channel

Synonyms: SCN5A, CDCD2, CMPD2, HB1, HB2, HH1, HBBD, Nav1.5, IVF, RSKM2X, SCAL, Scn2x, LQT3, SSS1, MH1, VF1, PFHB1, RATRSKM2X, SkM2, CMD1E, ICCD, RH1, RSkM2

Gen-ID: 6331

NCBI Accession: NP_932173, NP_000326, NP_001092874, NP_001092875, NP_001153632, NP_001153633

UniProt: Q14524