HLA-DQA2 Antikörper (AA 40-50)

Produktnummer ABIN1102096

Produktdetails anti-HLA-DQA2 Antikörper

Target: HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))

Bindungsspezifität: AA 40-50

Reaktivität: Human, Schaf, Rind (Kuh), Ziege

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser HLA-DQA2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human HLA-DQA2.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Sheep, Goat, Bovine (100%) Chimpanzee, Zebu (91%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-QSHGPSGQYTH from an internal region of human HLA-DQA2 (NP_064440.1). Percent identity by BLAST analysis: Human, Gorilla, Sheep, Goat, Bovine (100%), Chimpanzee, Zebu (91%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:16000)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Preliminary experiments gave bands at approx 35kD and 24kD in Human Lymph Node and Tonsil lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 28.0kD according to NP_064440.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu HLA-DQA2

Target: HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))

Andere Bezeichnung: HLA-DQA2 (HLA-DQA2 Produkte)

Synonyme: DX-ALPHA antikoerper, HLA-DXA antikoerper, major histocompatibility complex, class II, DQ alpha 2 antikoerper, HLA-DQA2 antikoerper

Hintergrund: Name/Gene ID: HLA-DQA2

Synonyms: HLA-DQA2, DX-ALPHA, DX alpha chain, MHC class II DQA2, HLA-DXA

Gen-ID: 3118

NCBI Accession: NP_064440

UniProt: P01906

Pathways: T-Zell Rezeptor Signalweg