LMX1B Antikörper (C-Term)

Produktnummer ABIN1077396

Produktdetails anti-LMX1B Antikörper

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMX1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: At least three isoforms are known to exist. This antibody is predicted to not cross-react with LMX1A.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LMX1B antibody can be used for detection of LMX1B by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Kommentare:

(CT) LIM homeobox transcription factor 1 beta

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: LMX1B antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu LMX1B

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Andere Bezeichnung: LMX1B (LMX1B Produkte)

Synonyme: LMX1.2 antikoerper, NPS1 antikoerper, LMX antikoerper, LMX1 antikoerper, LMX1.1 antikoerper, lmx1b antikoerper, lmx1b.1 antikoerper, Xlmx1b antikoerper, lmx1b.2 antikoerper, LIM homeobox transcription factor 1 beta antikoerper, LIM homeobox transcription factor 1, beta b antikoerper, LIM homeobox transcription factor 1, beta, gene 1 S homeolog antikoerper, LIM homeobox transcription factor 1, beta a antikoerper, LMX1B antikoerper, Lmx1b antikoerper, lmx1bb antikoerper, lmx1b.1.S antikoerper, lmx1ba antikoerper

Hintergrund: The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning, LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.
Synonyms: LIM homeobox transcription factor 1 beta, LIM/homeobox protein LMX1B, LIM/homeobox protein 1.2

Molekulargewicht: 45 kDa

Gen-ID: 4010

NCBI Accession: NP_001167617

Pathways: Dopaminergic Neurogenesis