CITED2 Antikörper (N-Term)

Produktnummer ABIN1077387

Produktdetails anti-CITED2 Antikörper

Target: CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CITED2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: Multiple isoforms of CITED2 are known to exist.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: CITED2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CITED2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CITED2 antibody can be used for detection of CITED2 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Kommentare:

(NT) Cbp/p300-interacting transactivator 2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: CITED2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu CITED2

Target: CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))

Andere Bezeichnung: CITED2 (CITED2 Produkte)

Synonyme: mrg1 antikoerper, p35srj antikoerper, zgc:103418 antikoerper, CITED2 antikoerper, cite2 antikoerper, ASD8 antikoerper, MRG-1 antikoerper, MRG1 antikoerper, P35SRJ antikoerper, VSD2 antikoerper, AI835299 antikoerper, ER154-like antikoerper, Mrg1 antikoerper, Msg2 antikoerper, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 antikoerper, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 antikoerper, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 antikoerper, Cbp/p300-interacting transactivator 2 antikoerper, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 L homeolog antikoerper, cited2 antikoerper, CITED2 antikoerper, cite2 antikoerper, Cited2 antikoerper, cited2.L antikoerper

Hintergrund: CITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1, a melanocyte-specific nuclear protein. CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2. CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf. CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs), with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs, multilineage bone marrow failure and increased lethality.
Synonyms: Cbp/p300-interacting transactivator 2, melanocyte-specific gene 1-related gene 1, MSG-related protein 1, MRG1, melanocyte specific gene 2, MSG2, ER154-like, ASD8, VSD2

Molekulargewicht: 30 kDa

Gen-ID: 10370

NCBI Accession: NP_001161861

Pathways: Tube Formation