CITED2 Antikörper (Internal Region)
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- Target Alle CITED2 Antikörper anzeigen
- CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CITED2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- CITED2 Antibody detects endogenous levels of total CITED2.
- Homologie
- Pig,Bovine,Sheep,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CITED2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CITED2 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))
- Andere Bezeichnung
- CITED2 (CITED2 Produkte)
- Synonyme
- mrg1 antikoerper, p35srj antikoerper, zgc:103418 antikoerper, CITED2 antikoerper, cite2 antikoerper, ASD8 antikoerper, MRG-1 antikoerper, MRG1 antikoerper, P35SRJ antikoerper, VSD2 antikoerper, AI835299 antikoerper, ER154-like antikoerper, Mrg1 antikoerper, Msg2 antikoerper, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 antikoerper, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 antikoerper, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 antikoerper, Cbp/p300-interacting transactivator 2 antikoerper, Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 L homeolog antikoerper, cited2 antikoerper, CITED2 antikoerper, cite2 antikoerper, Cited2 antikoerper, cited2.L antikoerper
- Hintergrund
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Description: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor, interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis, potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP), stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.
Gene: CITED2
- Molekulargewicht
- 28 kDa
- Gen-ID
- 10370
- UniProt
- Q99967
- Pathways
- Tube Formation
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