beta-2 Microglobulin Antikörper

Produktnummer ABIN1045266

Produktdetails anti-beta-2 Microglobulin Antikörper

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta-2 Microglobulin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Spezifität: Specific for B2M denatured and native forms

Kreuzreaktivität: Human

Aufreinigung: Protein G purified

Reinheit: > 95 %

Immunogen: Recombinant human Beta-2-microglobulin protein

Klon: 2D3E5

Isotyp: IgG1, IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution:IHC:1:50-1:500,

Kommentare:

Other species are not tested. Please decide the specificity by homology

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Referenzen für anti-beta-2 Microglobulin Antikörper (ABIN1045266)

Stefanović, Djukanović, Cukuranović, Bukvić, Ležaić, Marić, Ogrizovic, Jovanović, Vlahovic, Pešić, Djordjević: "Beta2-microglobulin and alpha1-microglobulin as markers of Balkan endemic nephropathy, a worldwide disease." in: Renal failure, Vol. 33, Issue 2, pp. 176-83, (2011) (PubMed).

Sharifiaghdas, Kashi, Eshratkhah: "Evaluating percutaneous nephrolithotomy-induced kidney damage by measuring urinary concentrations of β2-microglobulin." in: Urology journal, Vol. 8, Issue 4, pp. 277-82, (2011) (PubMed).

Johnston, Cassidy, OConnell, ORiordan, Gallagher, Maguire, Wynne, Cagney, Ryan, Conlon, McMorrow: "Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods." in: Proteomics. Clinical applications, Vol. 5, Issue 7-8, pp. 422-31, (2011) (PubMed).

Kals, Zagura, Serg, Kampus, Zilmer, Unt, Lieberg, Eha, Peetsalu, Zilmer: "β2-microglobulin, a novel biomarker of peripheral arterial disease, independently predicts aortic stiffness in these patients." in: Scandinavian journal of clinical and laboratory investigation, Vol. 71, Issue 4, pp. 257-63, (2011) (PubMed).

Dieterle, Perentes, Cordier, Roth, Verdes, Grenet, Pantano, Moulin, Wahl, Mahl, End, Staedtler, Legay, Carl, Laurie, Chibout, Vonderscher, Maurer: "Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury." in: Nature biotechnology, Vol. 28, Issue 5, pp. 463-9, (2010) (PubMed).

Details zu beta-2 Microglobulin

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Andere Bezeichnung: B2M (B2M Produkte)

Synonyme: Ly-m11 antikoerper, beta2-m antikoerper, beta2m antikoerper, bwm antikoerper, wu:fa94c05 antikoerper, wu:fb10a09 antikoerper, b2m-W01 antikoerper, b2m-W03 antikoerper, b2m-Z01 antikoerper, b2m-Z02 antikoerper, b2m-Z03 antikoerper, B2M antikoerper, b2m antikoerper, B2MG antikoerper, wu:fb66f11 antikoerper, wu:fj01f08 antikoerper, zgc:64161 antikoerper, b-2-m antikoerper, beta-2-microglobulin antikoerper, beta-2 microglobulin antikoerper, beta-2-microglobulin S homeolog antikoerper, beta-2-microglobulin, like antikoerper, B2M antikoerper, B2m antikoerper, b2m antikoerper, b2m.S antikoerper, b2ml antikoerper

Hintergrund:

Background: Beta 2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.

Aliases: B2M, CDABP0092, HDCMA22P

UniProt: P61769

Pathways: T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process