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General |
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Antigen | Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2) Antikörper |
Epitop | AA 127-155, Middle Region Alternativen |
Reaktivität | Human, Maus Alternativen |
Wirt | Kaninchen Alternativen |
Klonalität | |
Konjugat | Dieser CYP11B2 Antikörper ist unkonjugiert Alternativen |
Applikation |
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternativen
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1 Publikation vorhanden |
Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-CYP11B2 AntikörperTarget Details CYP11B2 Anwendungsinformationen Handhabung Referenzen für anti-CYP11B2 Antikörper (ABIN951773) Bilder |
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Spezifität | This antibody recognizes Human and Mouse CYP11B2 (Center). |
Reinigung | Affinity Chromatography on Protein A |
Immunogen | KLH conjugated synthetic peptide between 127-155 amino acids from the Central region of Human CYP11B2. Genename: CYP11B2 |
Isotyp | Ig Fraction |
Plasmids, Primers & others | |
Target Details CYP11B2Produktdetails anti-CYP11B2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CYP11B2 Antikörper (ABIN951773) Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | CYP11B2 (CYP11B2 Antibody Abstract) |
Hintergrund | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.Synonyms: ALDOS, Aldosterone synthase, Aldosterone-synthesizing enzyme, CYPXIB2, Cytochrome P450 11B2, P-450Aldo, P-450C18, Steroid 18-hydroxylase |
Molekulargewicht | 57560 Da |
Gen-ID | 1585 |
NCBI Accession | NP_000489 |
Pathways | ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour |
AnwendungsinformationenProduktdetails anti-CYP11B2 Antikörper Target Details CYP11B2 Handhabung Referenzen für anti-CYP11B2 Antikörper (ABIN951773) Bilder zurück nach oben |
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Applikations-hinweise | Optimal working dilution should be determined by the investigator. |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-CYP11B2 Antikörper Target Details CYP11B2 Anwendungsinformationen Referenzen für anti-CYP11B2 Antikörper (ABIN951773) Bilder zurück nach oben |
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Format | Liquid |
Konzentration | 0.25 mg/mL |
Buffer | PBS, 0.09 % Sodium Azide |
Konservierungs-mittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handhabung | Avoid repeated freezing and thawing. |
Lagerung | 4 °C/-20 °C |
Informationen zur Lagerung | Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. |
Referenzen für anti-CYP11B2 Antikörper (ABIN951773)Produktdetails anti-CYP11B2 Antikörper Target Details CYP11B2 Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Allgemeine Veröffentlichungen |
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 |
BilderProduktdetails anti-CYP11B2 Antikörper Target Details CYP11B2 Anwendungsinformationen Handhabung Referenzen für anti-CYP11B2 Antikörper (ABIN951773) zurück nach oben |
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Bilder des Herstellers |