BAFF and Receptor Detection Set

Produktnummer ABIN2455998

Produktdetails

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Aufreinigung: Antibodies are supplied as affinity chromatography purified IgG.

Bestandteile: BAFF Antibody, (50 μg)
APRIL Antibody, (50 μg)
TACI Antibody, (50 μg)
BCMA Antibody, (50 μg)
BAFF-R Antibody, (50 μg)

Anwendungsinformationen

Applikationshinweise: These polyclonal antibodies can be used for detection of BAFF and its receptors by Western blot at 2 μg/mL to 1 μg/mL, Immunohistochemistry, and Immunoflourescence. Whole cell lysate from HepG2 cells can be used as a positive control for each antibody except BAFF-R antibody, murine spleen lysate can be used as a positive control for that.
Optimal dilutions for each application to be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Stable at 4 °C for three months, store at -20 °C for up to one year.

Haltbarkeit: 12 months

Antigendetails

Hintergrund: Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members were recently identified by several groups and designated BAFF and APRIL. Both proteins stimulate B cell proliferation, humoral immune responses, NF-κB activation, and apoptosis. Two receptors, TACI and BCMA, recognize both BAFF and APRIL, a third receptor, BAFF-R, is specific for BAFF. These ligands and their receptors are involved in the development of autoimmune diseases as well as cancer.