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WDR33 encodes a member of the WD repeat protein family. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.
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Cow (Bovine) Polyclonal WDR33 Primary Antibody für WB - ABIN2781910
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
The authors define the molecular architecture of the core human CPSF (zeige CPSF3 Antikörper) complex comprising CPSF160 (zeige CPSF1 Antikörper), WDR33, CPSF30 (zeige CPSF4 Antikörper) and Fip1 (zeige RRAGA Antikörper) and identify specific domains involved in inter-subunit interactions. Together, these results shed light on the function of CPSF (zeige CPSF3 Antikörper) in mediating polyA signal-dependent RNA cleavage and polyadenylation.
unexpectedly found that CPSF (zeige CPSF3 Antikörper) subunits CPSF30 (zeige CPSF4 Antikörper) and Wdr33 directly contact AAUAAA
showed that WDR33 binds in and very close to the AAUAAA signal in vivo with high specificity
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
WD repeat-containing protein 33
, WD repeat domain 33
, WD repeat-containing protein 33-like
, WD repeat-containing protein WDC146
, pre-mRNA 3' end processing protein WDR33
, WD-repeat protein 33