anti-Ubiquitin Specific Peptidase 4 (USP4) Antikörper

The protein encoded by USP4 is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. Zusätzlich bieten wir Ihnen USP4 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP4 7375 Q13107
USP4 22258 P35123
USP4 290864 B2GUZ1
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Top anti-USP4 Antikörper auf antikoerper-online.de

Showing 10 out of 112 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Meerschweinchen Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB USP4 Antibody (N-term) western blot analysis in human uterine tumor tissue lysates (35 µg/lane). This demonstrates the USP4 antibody detected the USP4 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded A549 xenograft, using USP4, antibody at 1:500 dilution. IHC-P Image USP4 antibody detects USP4 protein at cytoplasm in mouse muscle by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. USP4 antibody , diluted at 1:500. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-USP4 C-term Pab (ABIN388883) is used in Western blot to detect USP4 in USP4-transfected HeLa cell lysate. Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Immunohistochemistry-Paraffin: USP4 Antibody  - Anti-USP4 / UNP antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IP 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot: USP4 Antibody  - Detection of Human and Mouse USP4 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-USP4 antibody  used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert IHC (p) 50 μg Anmelden zum Anzeigen 3 bis 4 Tage
$560.35
Details

USP4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)



Am meisten referenzierte anti-USP4 Antikörper

  1. Human Polyclonal USP4 Primary Antibody für IHC (p) - ABIN2477041 : Janík, Kubícková: [The picture of the mentally sick in our daily newspapers (author's transl)]. in Ceskoslovenská psychiatrie 1975 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal USP4 Primary Antibody für IP - ABIN251347 : Yang, Xia, Hermance, Mabb, Simonson, Morrissey, Gandhi, Munson, Miyamoto, Kelliher: A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage. in Molecular and cellular biology 2011 (PubMed)

  3. Human Polyclonal USP4 Primary Antibody für IP, WB - ABIN251348 : Song, Werner, Neubauer, Stegmeier, Aspden, Rio, Harper, Elledge, Kirschner, Rape: The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome. in Genes & development 2010 (PubMed)

  4. Human Polyclonal USP4 Primary Antibody für IHC (p), WB - ABIN388883 : Laurell, Velázquez-Fernández, Lindsten, Juhlin, Enberg, Geli, Höög, Kjellman, Lundeberg, Hamberger, Larsson, Nilsson, Bäckdahl: Transcriptional profiling enables molecular classification of adrenocortical tumours. in European journal of endocrinology / European Federation of Endocrine Societies 2009 (PubMed)

Weitere Antikörper gegen USP4 Interaktionspartner

Human Ubiquitin Specific Peptidase 4 (USP4) Interaktionspartner

  1. These results identify USP4 as a novel regulator of Dvl (zeige DVL2 Antikörper) in Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signal and show its involvement in Wnt3a (zeige WNT3A Antikörper)-induced osteoblast differentiation

  2. Data suggest that ubiquitin specific protease 4 (USP4) interacts with interferon regulatory factor 8 (IRF8 (zeige IRF8 Antikörper)) and, by its Lys48-specific deubiquitinase/endopeptidase activity, stabilizes IRF8 (zeige IRF8 Antikörper) protein levels in regulatory T-lymphocytes; USP4 and IRF8 (zeige IRF8 Antikörper) are also expressed in helper T-lymphocytes.

  3. USP4 inhibits p53 (zeige TP53 Antikörper) and NF-kappaB (zeige NFKB1 Antikörper) through deubiquitinating and stabilizing HDAC2 (zeige HDAC2 Antikörper)

  4. ubiquitin-specific protease 4 (USP4) is a binding partner of RNPS1 (zeige RNPS1 Antikörper).

  5. Data indicate that programmed cell death 4 (PDCD4 (zeige PDCD4 Antikörper)) was identified to be a target of ubiquitin-specific protease 4 (USP4), which plays a role as a tumor suppressor.

  6. Ubiquitin-specific protease 4 (USP4), recently identified as a beta (zeige SUCLA2 Antikörper)-catenin (zeige CTNNB1 Antikörper)-specific deubiquitinylating enzyme, was highly expressed in PC14PE6/LvBr4 cells and involved in the increased stability of beta-catenin (zeige CTNNB1 Antikörper) protein.

  7. USP4 knockdown in HCT116, a colon cancer cell line, reduced invasion and migration activity.

  8. USP4 cooperates with CtIP (zeige RBBP8 Antikörper) in DNA double-strand break end resection.

  9. Results demonstrate that aberrant expression of USP4 contributes to the development and progression of colorectal cancer and reveal a critical mechanism underlying USP4-mediated oncogenic activity.

  10. findings thus identify USP4 as a novel DNA repair regulator and invoke a model in which ubiquitin adducts regulate USP enzyme interactions and functions.

Mouse (Murine) Ubiquitin Specific Peptidase 4 (USP4) Interaktionspartner

  1. In this study, we identified ubiquitin-specific protease 4 (USP4), one of deubiquitinating enzymes, as a suppressor of MRFs by demonstrating that a knockdown of USP4 enhances myogenesis by controlling MyoD (zeige MYOD1 Antikörper) and the level of myogenesis marker proteins in C2C12 cells... we propose that USP4 is a key player in myogenic differentiation; it controls myogenic regulatory factors in a catalytic-independent manner

  2. The authors demonstrated that ubiquitin-specific protease (USP) 4 strongly induces activin (zeige Actbeta Antikörper)/BMP signaling by removing the inhibitory monoubiquitination from SMAD4 (zeige SMAD4 Antikörper).

  3. USP4 plays an essential role in negative regulation of the TLR/IL-1R signaling-mediated innate immune response

  4. Results uncover USP4 as an important determinant for crosstalk between TGF-beta/TGF-beta (zeige TGFB1 Antikörper) type I receptor (zeige TGFBR1 Antikörper) and AKT (zeige AKT1 Antikörper) signalling pathways.

  5. USP4 interacts directly with and deubiquitinates ARF-BP1, leading to the stabilization of ARF-BP1 and subsequent reduction of p53 (zeige TP53 Antikörper) levels.

  6. the existence of a nuclear export signal ((133)VEVYLLELKL(142)) in Usp4;Usp4 is thus the first oncogenic deubiquitylating enzyme reported to have nucleocytoplasmic shuttling properties.

USP4 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit USP4

  • ubiquitin specific peptidase 4 (USP4) Antikörper
  • ubiquitin specific peptidase 4 (proto-oncogene) (Usp4) Antikörper
  • ubiquitin specific peptidase 4 (Usp4) Antikörper
  • F730026I20Rik Antikörper
  • mKIAA4155 Antikörper
  • Unp Antikörper
  • Unph Antikörper

Bezeichner auf Proteinebene für USP4

ubiquitin specific protease 4 , deubiquitinating enzyme 4 , ubiquitin carboxyl-terminal esterase 4 , ubiquitin carboxyl-terminal hydrolase 4 , ubiquitin specific protease 4 (proto-oncogene) , ubiquitin thioesterase 4 , ubiquitin thiolesterase 4 , ubiquitin-specific processing protease 4 , ubiquitous nuclear protein homolog , ubiquitin-specific-processing protease 4 , ubiquitous nuclear protein

GENE ID SPEZIES
100228772 Taeniopygia guttata
7375 Homo sapiens
22258 Mus musculus
290864 Rattus norvegicus
508042 Bos taurus
Ausgewählte Anbieter für anti-USP4 (USP4) Antikörper
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