anti-Ubiquitin Specific Peptidase 28 (USP28) Antikörper

The ubiquitin-dependent protein degradation pathway is essential for proteolysis of intracellular proteins and peptides. Zusätzlich bieten wir Ihnen USP28 Proteine (5) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP28 57646 Q96RU2
USP28 235323 Q5I043
USP28 315639 D3ZJ96
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Top anti-USP28 Antikörper auf antikoerper-online.de

Showing 10 out of 104 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: USP28 Antibody  - Analysis in human cell line A-549. Western Blot: USP28 Antibody  - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC (p), IP, IHC, PLA, WB Immunohistochemistry-Paraffin: USP28 Antibody [ABIN2581863] - FFPE section of human stomach adenocarcinoma. Affinity purified rabbit anti-USP28 used at a dilution of 1:250. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, IHC, IHC (p) Anti-USP28 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962695 concentration 41396 ug/ml. Anti-USP28 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962695 concentration 41396 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 7.5% SDS PAGE USP28 antibody antibody diluted at 1:500 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB The anti-USP28 Pab (ABIN388921) is used in Western blot to detect USP28 in Jurkat cell lysate. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Rind (Kuh) Ziege Unkonjugiert EIA, IHC (p) Staining of paraffin embedded Human Testis using USP28 antibody at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: USP28 Antibody [ABIN4091101] - 3.8ug/ml staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$450.00
Details

Am meisten referenzierte anti-USP28 Antikörper

  1. Human Polyclonal USP28 Primary Antibody für IHC (p), IHC - ABIN409110 : Popov, Herold, Llamazares, Schülein, Eilers: Fbw7 and Usp28 regulate myc protein stability in response to DNA damage. in Cell cycle (Georgetown, Tex.) 2007 (PubMed)

  2. Human Polyclonal USP28 Primary Antibody für ICC, IF - ABIN4364574 : Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012 (PubMed)

Weitere Antikörper gegen USP28 Interaktionspartner

Human Ubiquitin Specific Peptidase 28 (USP28) Interaktionspartner

  1. The authors identified 53BP1 (zeige TP53BP1 Antikörper) and USP28 as essential components acting upstream of p53 (zeige TP53 Antikörper), evoking p21 (zeige CDKN1A Antikörper)-dependent cell cycle arrest in response not only to centrosome loss, but also to other distinct defects causing prolonged mitosis.

  2. USP28 controls activation of both the TP53 (zeige TP53 Antikörper) branch and the GATA4 (zeige GATA4 Antikörper)/NFkB branch that controls the senescence-associated secretory phenotype (SASP (zeige ASPRV1 Antikörper))

  3. 53BP1 (zeige TP53BP1 Antikörper)-USP28 cooperation is essential for normal p53 (zeige TP53 Antikörper)-promoter element interactions and gene transactivation-associated events, yet dispensable for 53BP1 (zeige TP53BP1 Antikörper)-dependent DNA double-strand repair regulation.

  4. USP28-53BP1 (zeige TP53BP1 Antikörper)-p53 (zeige TP53 Antikörper)-p21 (zeige CDKN1A Antikörper) signaling pathway is also required to arrest cell growth after a prolonged prometaphase.

  5. analysis of centrinone resistance identified a 53BP1 (zeige TP53BP1 Antikörper)-USP28 module as critical for communicating mitotic challenges to the p53 (zeige TP53 Antikörper) circuit and TRIM37 (zeige TRIM37 Antikörper) as an enforcer of the singularity of centrosome assembly.

  6. These results showed that USP28 is overexpressed in human glioblastomas and it contributes to glioma tumorigenicity.

  7. Data indicte that deubiquitinating enzyme USP28 was targeted by microRNA miR (zeige MLXIP Antikörper)-4295.

  8. findings provide a first insight into understanding how the enzymatic activity of Usp28 is regulated by its non-catalytic UBR and endogenous ligands.

  9. Dual regulation of Fbw7 (zeige FBXW7 Antikörper) activity by Usp28 is a safeguard mechanism for maintaining physiological levels of proto-oncogenic Fbw7 (zeige FBXW7 Antikörper) substrates, which is equivalently disrupted by loss or overexpression of Usp28.

  10. identified Usp28 as a c-MYC (zeige MYC Antikörper) target gene highly expressed in colorectal cancers, which indicates that USP28 and c-MYC (zeige MYC Antikörper) form a positive feedback loop that maintains high c-MYC (zeige MYC Antikörper) protein levels in tumors

Mouse (Murine) Ubiquitin Specific Peptidase 28 (USP28) Interaktionspartner

  1. In mice, an unusually direct antagonism between an E3 ligase and a deubiquitinase, Fbw7 (zeige FBXW7 Antikörper) and Usp28, modulate intestinal homeostasis and cancer.

  2. Dual regulation of Fbw7 (zeige FBXW7 Antikörper) activity by Usp28 is a safeguard mechanism for maintaining physiological levels of proto-oncogenic Fbw7 (zeige FBXW7 Antikörper) substrates, which is equivalently disrupted by loss or overexpression of Usp28.

  3. identified Usp28 as a c-MYC (zeige MYC Antikörper) target gene highly expressed in colorectal cancers, which indicates that USP28 and c-MYC (zeige MYC Antikörper) form a positive feedback loop that maintains high c-MYC (zeige MYC Antikörper) protein levels in tumors

USP28 Antigen-Profil

Protein Überblick

The ubiquitin-dependent protein degradation pathway is essential for proteolysis of intracellular proteins and peptides. Enzymes that remove ubiquitin from ubiquitin-conjugated peptides, like USP28, affect the fate and degradation of intracellular proteins and are essential for maintenance of cell-free ubiquitin pools (Valero et al., 2001).

Genbezeichner und Symbole assoziert mit USP28

  • ubiquitin specific peptidase 28 (USP28) Antikörper
  • ubiquitin specific peptidase 28 (usp28) Antikörper
  • ubiquitin specific peptidase 28 (Usp28) Antikörper
  • 9830148O20Rik Antikörper
  • AU022237 Antikörper
  • im:7138195 Antikörper
  • mKIAA1515 Antikörper
  • USP28 Antikörper

Bezeichner auf Proteinebene für USP28

ubiquitin specific peptidase 28 , ubiquitin carboxyl-terminal hydrolase 28-like , ubiquitin specific protease 28 , ubiquitin carboxyl-terminal hydrolase 28 , deubiquitinating enzyme 28 , ubiquitin carboxyl-terminal hydrolase 28 variant 1 , ubiquitin thioesterase 28 , ubiquitin thiolesterase 28 , ubiquitin-specific-processing protease 28

GENE ID SPEZIES
100032176 Monodelphis domestica
100402269 Callithrix jacchus
100468031 Ailuropoda melanoleuca
100492386 Xenopus (Silurana) tropicalis
567050 Danio rerio
696672 Macaca mulatta
100232055 Taeniopygia guttata
100346849 Oryctolagus cuniculus
100558297 Anolis carolinensis
100591669 Nomascus leucogenys
508902 Bos taurus
57646 Homo sapiens
235323 Mus musculus
489400 Canis lupus familiaris
100519614 Sus scrofa
315639 Rattus norvegicus
428246 Gallus gallus
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