anti-UPF3 Regulator of Nonsense Transcripts Homolog B (Yeast) (UPF3B) Antikörper

UPF3B encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. Zusätzlich bieten wir Ihnen UPF3B Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UPF3B 65109 Q9BZI7
UPF3B 68134  
UPF3B 313449  
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Top anti-UPF3B Antikörper auf antikoerper-online.de

Showing 10 out of 22 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-UPF3B Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- UPF3B/RENT3B Picoband antibody, IHC(P) IHC(P): Rat Testis Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Hund Kaninchen Unkonjugiert IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: UPF3B Antibody  - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol. Western Blot: UPF3B Antibody  - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells). 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert WB Western Blot: UPF3B Antibody [NBP1-57233] - Titration: 0.2-1 ug/ml, Positive Control: Human heart. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IHC, WB UPF3B antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain EpitheliaI cells of fundic gland (arrows) in Human Stomach. Magnification is at 400X UPF3B antibody used at 1.25 ug/ml to detect target protein. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$388.93
Details

UPF3B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human


Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-UPF3B Antikörper

  1. Cow (Bovine) Polyclonal UPF3B Primary Antibody für IHC, WB - ABIN2776563 : Lehner, Sanderson: A protein interaction framework for human mRNA degradation. in Genome research 2004 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen UPF3B Interaktionspartner

Human UPF3 Regulator of Nonsense Transcripts Homolog B (Yeast) (UPF3B) Interaktionspartner

  1. The authors discovered that UPF3B (i) interacts with the release factors, (ii) delays translation termination and (iii) dissociates post-termination ribosomal complexes that are devoid of the nascent peptide.

  2. UPF3B gene mutation is associated with Lujan-Fryns syndrome.

  3. the neurodevelopmental phenotype of UPF3B missense mutation is caused by impairment of nonsense-mediated mRNA decay pathway function altering neuronal differentiation.

  4. These findings indicate that SATB2 (zeige SATB2 Antikörper) activates UPF3B expression through binding to its promoter.

  5. Data indicate the mutation p.R430X of UPF3B gene as the genetic etiology in the mental retardation pedigree.

  6. results demonstrate that the UPF3B-dependent NMD pathway is a major regulator of the transcriptome and that its targets have important roles in neuronal cells.

  7. The two cases with renal dysplasia and developmental delay showed remarkable clinical variability despite having the same mutation in UPF3B.

  8. Our results demonstrate that in addition to Lujan-Fryns and FG syndromes, UPF3B protein truncation mutations can cause also nonspecific XLMR (zeige DLG3 Antikörper).

  9. 3.4 A resolution crystal structure of a minimal UPF3b-EJC assembly, consisting of the interacting domains of five proteins (UPF3b, MAGO (zeige MAGOHB Antikörper), Y14 (zeige RBM8A Antikörper), eIF4AIII (zeige EIF4A3 Antikörper), and Barentsz (zeige CASC3 Antikörper)) together with RNA and adenylyl-imidodiphosphate

  10. A conserved domain of hUpf3b mediates an interaction with the EJC protein Y14 (zeige RBM8A Antikörper). Y14 (zeige RBM8A Antikörper) is required for nonsense-mediated decay induced by tethered hUpf3b.

Mouse (Murine) UPF3 Regulator of Nonsense Transcripts Homolog B (Yeast) (UPF3B) Interaktionspartner

  1. Analysis revealed that UPF3A (zeige UPF3A Antikörper) is a broadly acting nonsense-mediated RNA decay inhibitor. This discovery implies that UPF3A (zeige UPF3A Antikörper) and UPF3B do not primarily work in a complementary or redundant manner as previously supposed; instead, they oppose each other, allowing this paralog pair to serve as a molecular rheostat to modulate the level of gene expression during development.

  2. Evidence suggests Upf3b-dependent nonsense-mediated mRNA decay is regulated at multiple levels during development including regulation of expression and sub-cellular localization of Upf3b.

UPF3B Antigen-Profil

Protein Überblick

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit UPF3B

  • UPF3B, regulator of nonsense mediated mRNA decay (UPF3B) Antikörper
  • UPF3 regulator of nonsense transcripts homolog B (yeast) (Upf3b) Antikörper
  • UPF3B, regulator of nonsense mediated mRNA decay (Upf3b) Antikörper
  • 5730594O13Rik Antikörper
  • AI317193 Antikörper
  • AW541158 Antikörper
  • HUPF3B Antikörper
  • MRXS14 Antikörper
  • RENT3B Antikörper
  • RGD1560264 Antikörper
  • UPF3X Antikörper

Bezeichner auf Proteinebene für UPF3B

hUpf3p-X , nonsense mRNA reducing factor 3B , regulator of nonsense transcripts 3B , up-frameshift suppressor 3 homolog B , up-frameshift suppressor 3 homolog on chromosome X , hUPF3B

GENE ID SPEZIES
65109 Homo sapiens
481031 Canis lupus familiaris
616181 Bos taurus
68134 Mus musculus
313449 Rattus norvegicus
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