anti-U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1) Antikörper

U2AF1 belongs to the splicing factor SR family of genes. Zusätzlich bieten wir Ihnen U2AF1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
U2AF1 108121 Q9D883
U2AF1 7307 Q01081
U2AF1 687575  
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Top anti-U2AF1 Antikörper auf antikoerper-online.de

Showing 10 out of 45 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-U2AF1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human Stomach 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IP, IHC (p), WB WB Image Sample(30μg whole cell lysate) A: 293T B: A431 , C: H1299 D: HeLa S3 , E: Hep G2 , F: MOLT4 , G: Raji , 12% SDS PAGE antibody diluted at 1:1000 IP Image Immunoprecipitation of U2AF35 protein from 293T whole cell extracts using 5 μg of U2AF35 antibody, Western blot analysis was performed using U2AF35 antibody, EasyBlot anti-Rabbit IgG  was used as a secondary reagent. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of anti-U2AF1 Antibody (Center Y114) (ABIN389305) in Ramos cell line lysates (35 µg/lane).U2AF1(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with NRP1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with U2AF1 antibody (Center S70), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-U2AF1 Antibody (Center S70) (ABIN389304) in Ramos cell line lysates (35 µg/lane).U2AF1(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: U2AF35 Antibody [NBP1-32515] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution. Immunohistochemistry-Paraffin: U2AF35 Antibody [NBP1-32515] - Paraffin-embedded DU145 xenograft, using antibody at 1:100 dilution. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: U2AF35 Antibody [NBP1-19120] - FFPE section of mouse colon carcinoma. Antibody used at a dilution of 1:250. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: U2AF35 Antibody  - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm. Immunohistochemistry-Paraffin: U2AF35 Antibody  - Staining of human hippocampus shows moderate nuclear positivity in neuronal cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cells, using U2AF1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details

U2AF1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Mouse (Murine) ,


Human , ,
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Rat (Rattus) ,


Am meisten referenzierte anti-U2AF1 Antikörper

  1. Human Polyclonal U2AF1 Primary Antibody für ICC, IF - ABIN438948 : Wang, Wilson-Berry, Schedl, Hansen: TEG-1 CD2BP2 regulates stem cell proliferation and sex determination in the C. elegans germ line and physically interacts with the UAF-1 U2AF65 splicing factor. in Developmental dynamics : an official publication of the American Association of Anatomists 2012 (PubMed)

  2. Human Polyclonal U2AF1 Primary Antibody für ICC, IF - ABIN4363831 : Stadler, Fagerberg, Sivertsson, Oksvold, Zwahlen, Hallström, Lundberg, Uhlén: RNA- and antibody-based profiling of the human proteome with focus on chromosome 19. in Journal of proteome research 2014 (PubMed)

Weitere Antikörper gegen U2AF1 Interaktionspartner

Mouse (Murine) U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1) Interaktionspartner

  1. The U2AF35(S34F) mutation alters interaction with CFIm59 (zeige CPSF7 Antikörper), leading to increased use of a distal cleavage and polyadenylation site in the ATG7 (zeige ATG7 Antikörper) pre-mRNA, decreasing levels of ATG7 (zeige ATG7 Antikörper) protein and defective autophagy, ultimately leading to transformation.

  2. data support the impact of genes from the Abcg1 (zeige ABCG1 Antikörper)-U2af1 region as modifiers of Tc1 (zeige C8orf4 Antikörper)-dependent memory and locomotor phenotypes in Tc1 (zeige C8orf4 Antikörper) mouse model of Down syndrome.

  3. findings support the hypothesis that mutant U2AF1 alters downstream gene isoform expression, thereby contributing to abnormal hematopoiesis in patients with MDS (zeige MECOM Antikörper)

  4. this study establishes definitely the contribution of the Abcg1 (zeige ABCG1 Antikörper)-U2af1 orthologous region to the DS etiology and suggests new modulatory pathways for learning and memory.

Human U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1) Interaktionspartner

  1. data confirm MLL (zeige MLL Antikörper)-PTD (zeige BCS1L Antikörper) and, to a lesser extent, FLT3 (zeige FLT3 Antikörper)-ITD as common events in +11 AML (zeige RUNX1 Antikörper).6, 7, 8 However, the high mutation frequencies of U2AF1 and genes involved in methylation (DNMT3A (zeige DNMT3A Antikörper), IDH2 (zeige IDH2 Antikörper)) have hitherto not been reported in +11 AML (zeige RUNX1 Antikörper)

  2. this study characterized novel candidate pediatric T-cell acute lymphoblastic leukemia driver mutation in splicesome factor U2AF1

  3. U2AF35 missense mutation is associated with alternative 5' splice site that impacts splicing regulation in cancer.

  4. The frequently mutated SF3B1 (zeige SF3B2 Antikörper) residues contact the pre-mRNA splice site. Based on structural homology with other spliceosome subunits, and recent findings of altered RNA binding by mutant U2AF1 proteins, we suggest that affected U2AF1 residues also contact pre-mRNA.

  5. The aberrantly spliced target genes and deregulated cellular pathways associated with the commonly mutated splicing factor (zeige SLU7 Antikörper) genes in myelodysplastic syndromes (SF3B1 (zeige SF3B2 Antikörper), SRSF2 (zeige SRSF2 Antikörper) and U2AF1) are being identified, illuminating the molecular mechanisms underlying the disease. (Review)

  6. infer that U2AF1 S34 mutations characterize a distinct subgroup of myelodysplastic syndrome

  7. The U2AF35(S34F) mutation alters interaction with CFIm59 (zeige CPSF7 Antikörper), leading to increased use of a distal cleavage and polyadenylation site in the ATG7 (zeige ATG7 Antikörper) pre-mRNA, decreasing levels of ATG7 (zeige ATG7 Antikörper) protein and defective autophagy, ultimately leading to transformation.

  8. Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons controlled by SRF3.

  9. Our results provide mechanistic explanations of the magnitude of splicing changes observed in U2AF1-mutant cells and why tumors harboring U2AF1 mutations always retain an expressed copy of the wild-type allele

  10. Mutations in ASXL1 (zeige ASXL1 Antikörper), U2AF1, and SF3B1 (zeige SF3B2 Antikörper) are common in Chinese patients with myelodysplastic syndromes.

U2AF1 Antigen-Profil

Protein Überblick

This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit U2AF1

  • U2 small nuclear RNA auxiliary factor 1 (U2AF1) Antikörper
  • CCHC-type zinc finger-containing protein (u2af1) Antikörper
  • U2 small nuclear RNA auxiliary factor 1 (u2af1) Antikörper
  • splicing factor U2AF 35 kDa subunit (LOC737227) Antikörper
  • U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 (U2af1) Antikörper
  • U2 small nuclear RNA auxiliary factor 1 S homeolog (u2af1.S) Antikörper
  • U2 small nuclear RNA auxiliary factor 1 (U2af1) Antikörper
  • 35kDa Antikörper
  • 2010107D16Rik Antikörper
  • CHUNP6860 Antikörper
  • DDBDRAFT_0218665 Antikörper
  • DDBDRAFT_0233354 Antikörper
  • DDB_0218665 Antikörper
  • DDB_0233354 Antikörper
  • FP793 Antikörper
  • RN Antikörper
  • RNU2AF1 Antikörper
  • U2AF35 Antikörper
  • U2AFBP Antikörper
  • zgc:111896 Antikörper

Bezeichner auf Proteinebene für U2AF1

U2 small nuclear RNA auxiliary factor 1 , RNA recognition motif-containing protein RRM , RNA-binding region RNP-1 domain-containing protein , U2 snRNP auxiliary factor small subunit , U2(RNU2) small nuclear RNA auxiliary factor 1 , U2 auxiliary factor 35 kDa subunit , U2 small nuclear ribonucleoprotein auxiliary factor (U2AF),35 kDa , splicing factor U2AF 35 kDa subunit , U2 small nuclear RNA auxillary factor 1 , U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit , U2(RNU2) small nuclear RNA auxiliary factor binding protein , splicing factor U2AF 35kDa subunit , U2snRNP auxiliary factor small subunit , uncharacterized protein LOC687575 , U2(RNU2) small nuclear RNA auxillary factor 1

GENE ID SPEZIES
478422 Canis lupus familiaris
8624909 Dictyostelium discoideum AX4
733934 Xenopus (Silurana) tropicalis
737227 Pan troglodytes
108121 Mus musculus
7307 Homo sapiens
734926 Xenopus laevis
395370 Gallus gallus
512680 Bos taurus
687575 Rattus norvegicus
192328 Danio rerio
Ausgewählte Anbieter für anti-U2AF1 (U2AF1) Antikörper
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