anti-Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) Antikörper

SDHC encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. Zusätzlich bieten wir Ihnen SDHC Kits (9) und SDHC Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SDHC 66052 Q9CZB0
SDHC 289217  
SDHC 6391 Q99643
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Top anti-SDHC Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-SDHC antibody, IHC(P) IHC(P): Human Gastric Cancer Tissue Anti-SDHC antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: HELA Tissue Lysate Lane 3: JURKAT Cell Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-SDHC Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
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Human Kaninchen Unkonjugiert IF (p), IHC (p) Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti SDHC Polyclonal Antibody, Unconjugated (ABIN1385318) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$317.90
Details
Maus Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$360.00
Details
Human Maus Unkonjugiert WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (44.33 KDa) . Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$527.50
Details
Human Maus Unkonjugiert IHC, WB Immunoperoxidase of monoclonal antibody to SDHC on formalin-fixed paraffin-embedded human skeletal muscle (antibody concentration 3 µg/mL). Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (44.33 KDa) . Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$527.50
Details
Human Maus Unkonjugiert ELISA, IHC, IHC (p), WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$537.17
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of mouse heart, using SDHC antibody (ABIN5972253). 100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$412.19
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (44.33 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

Am meisten referenzierte anti-SDHC Antikörper

  1. Human Monoclonal SDHC Primary Antibody für ELISA, WB - ABIN520106 : Lemarie, Grimm: Mutations in the heme b-binding residue of SDHC inhibit assembly of respiratory chain complex II in mammalian cells. in Mitochondrion 2009 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen SDHC Interaktionspartner

Mouse (Murine) Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) Interaktionspartner

  1. Studies indicate that the Tet-mev-1 conditional transgenic system can induce mutated SDHC gene in complex II.

  2. complex II plays an essential role in hypoxic reactive oxygen species production.

  3. a sensor for apoptosis induction

Human Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) Interaktionspartner

  1. Targeted analysis of DNA methylation array revealed the mesenchymal stem cells in infants born to obese mothers had hypermethylation in genes regulating Fatty Acid Oxidation (PRKAG2, ACC2, CPT1A, SDHC) and corresponding lower mRNA content of these genes. Moreover, mesenchymal stem cells methylation was positively correlated with infant adiposity.

  2. SDHC Promoter hypermethylation is associated with Parasympathetic Paragangliomas.

  3. SDH-deficient gastrointestinal stromal tumors (GISTs) account for approximately 8% of gastric GISTs and are associated with a high rate of distant metastasis, regardless of conventional risk category.

  4. 31% of the paragangliomas in the French Canadian can be explained by the SDHC mutation (c.397C>T, p.[Arg133Ter]).

  5. For classification, tumors were characterized by SDHA, B, C, or D (SDHX) mutations and other genetic and epigenetic alterations, including presence of mutations in germline

  6. Heterozygous germline deletions of up to 104 kb in size were identified in SDHB, SDHC, SDHD and flanking genes in 20 paraganglioma-pheochromocytoma patients. The exact breakpoint could be determined in 16 paraganglioma-pheochromocytoma patients of which 15 were novel deletions

  7. According to international guidelines, SDHB, SDHC, and SDHD genetic testing were performed in this patient, but not SDHA, which would have been prescribed only after surgery, in case of SDHA negative immunohistochemistry

  8. Loss of the SDHC gene is associated with metastatic sympathetic paraganglioma.

  9. This report provides evidence that SDHC promoter methylation can cause Paragangliomas due to SDHC inactivation

  10. significant association with overall survival were confirmed for SDHC gene, SDHD gene and FH gene ... SDHC gene and FH gene were the primary factors contributing to the different overall survival time of colorectal carcinoma

  11. This study strengthens the etiological association of SDH genes with pituitary neoplasia, renal tumorigenesis, and gastric gastrointestinal stromal tumors. Also, pancreatic neuroendocrine tumor falls within the SDH-related tumor spectrum.

  12. Both germline and somatic SDHx mutations/variants occur in sporadic differentiated thyroid cancer (DTC) but are very rare in sporadic breast cancer, and overall loss of SDHx gene expression is a signature of DTC

  13. The discovery of SDHC epimutation provides a unifying explanation for the pathogenesis of SDH-deficient gastrointestinal stromal tumors.

  14. Variant in rs3935401 in the 3' untranslated region of SDHC is associated with hepatocellular carcinoma.

  15. these data suggest epigenetic inactivation of the SDHC gene locus with functional impairment of the SDHC as a plausible alternate mechanism of tumorigenesis in Carney Triad

  16. Overall, 9 of the 34 patients with KIT/PDGFRA wild-type GIST carried mutations in one of the four subunits of the SDH complex (six patients in SDHA, two in SDHB, one in SDHC

  17. Thoracic paragangliomas are common in patients with SDHC mutations, and imaging of this area should be included in surveillance of mutation carriers.

  18. this study reports the first patient affected by malignant paraganglioma and< moreover, it reports two more unrelated patients with the same genotype and very different clinical presentations.

  19. SDH deficiency may promote tumorigenesis through accumulation of succinate and inhibition of dioxygenase enzymes. Inhibition of TET activity may, in turn, alter global DNA methylation and gene expression in SDH-deficient tumors.

  20. Studies indicate that an array of tumor syndromes caused by complex II-associated mutations in genes SDHA, SDHB, SDHC, SDHD, SDHAF1 and SDHAF2 have been identified over a decade.

Cow (Bovine) Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) Interaktionspartner

  1. assignment to chromosome 2

SDHC Antigen-Profil

Protein Überblick

This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit SDHC

  • succinate dehydrogenase complex subunit C (SDHC) Antikörper
  • succinate dehydrogenase complex subunit C (sdhc) Antikörper
  • succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SdhC) Antikörper
  • succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SDHC) Antikörper
  • succinate dehydrogenase complex, subunit C, integral membrane protein (Sdhc) Antikörper
  • succinate dehydrogenase complex subunit C (Sdhc) Antikörper
  • 0610010E03Rik Antikörper
  • AI316496 Antikörper
  • AU019277 Antikörper
  • CYB560 Antikörper
  • CYBL Antikörper
  • PGL3 Antikörper
  • QPS1 Antikörper
  • SDH3 Antikörper
  • SDHC Antikörper

Bezeichner auf Proteinebene für SDHC

succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa , ENSANGP00000017418-like protein , OXPHOS complex II cytochrome B560 subunit , succinate dehydrogenase C , succinate dehydrogenase cytochrome b560 subunit, mitochondrial , QPs-1 , QPs1 , integral membrane protein CII-3 , succinate dehydrogenase complex, subunit C , cytochrome B large subunit of complex II , integral membrane protein CII-3b , succinate dehydrgenase cytochrome b , succinate dehydrogenase 3, integral membrane subunit , succinate-ubiquinone oxidoreductase cytochrome B large subunit , succinate dehydrogenase complex subunit C

GENE ID SPEZIES
478983 Canis lupus familiaris
496650 Xenopus (Silurana) tropicalis
719978 Macaca mulatta
747462 Pan troglodytes
100114948 Nasonia vitripennis
100126849 Sus scrofa
66052 Mus musculus
289217 Rattus norvegicus
6391 Homo sapiens
327696 Bos taurus
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