SDHC Antikörper (N-Term)

Produktnummer ABIN3032765

Produktdetails anti-SDHC Antikörper

Target: SDHC (Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SDHC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human Succinate dehydrogenase complex subunit C (KEEMERFWNKNIGSNR) was used as the immunogen for this SDHC antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the SDHC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the SDHC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu SDHC

Target: SDHC (Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC))

Andere Bezeichnung: SDHC (SDHC Produkte)

Synonyme: SDHC antikoerper, 0610010E03Rik antikoerper, AI316496 antikoerper, AU019277 antikoerper, CYB560 antikoerper, CYBL antikoerper, PGL3 antikoerper, QPS1 antikoerper, SDH3 antikoerper, succinate dehydrogenase complex subunit C antikoerper, succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa antikoerper, succinate dehydrogenase complex, subunit C, integral membrane protein antikoerper, SDHC antikoerper, sdhc antikoerper, SdhC antikoerper, Sdhc antikoerper

Hintergrund: The Succinate dehydrogenase complex, subunit C (SDHC), also called SDH3, gene contains 6 exons. Oostveen et al.(1995) found that in fact it was protein from the bovine SDHC/SDH3 gene (encoding 1 of the 2 integral membrane proteins) that complemented the hamster mutation. The authors localized the human SDH3 gene to the short arm of chromosome one, within 1 to 2 Mb from the centromere. Additionally, the authors stated that Southern analyses of human genomic DNA suggested that there are multiple SDH3 genes or pseudogenes. Elbehti-Green et al.(1998) confirmed the assignment of the SDHC gene to 1q21 by FISH. Baysal et al.(2004) described a family with PGL3 in which an 8,372-bp deletion in the SDHC gene was transmitted both maternally and paternally, without evidence of genomic imprinting.

UniProt: Q99643