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The protein encoded by SOAT1 belongs to the acyltransferase family. Zusätzlich bieten wir Ihnen SOAT1 Antikörper (17) und SOAT1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
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Intracranial GBM xenografts were used to determine the effects of genetically silencing SOAT1 and SREBP-1 (zeige SREBF1 ELISA Kits) on tumor growth.
Higher Gleason grade was associated with lower LDLR (zeige LDLR ELISA Kits) expression, lower SOAT1 and higher SQLE (zeige SQLE ELISA Kits) expression. Besides high SQLE (zeige SQLE ELISA Kits) expression, cancers that became lethal despite primary treatment were characterized by low LDLR (zeige LDLR ELISA Kits) expression (odds ratio for highest versus lowest quintile, 0.37; 95% CI 0.18-0.76) and by low SOAT1 expression (odds ratio, 0.41; 95% CI 0.21-0.83).
Data indicate that mitotane confers adrenal-specific cytotoxicity and down-regulates steroidogenesis by inhibition of sterol-O-acyl-transferase 1 (SOAT1) leading to lipid-induced endoplasmic reticulum (ER) stress.
Suggest retinal pigment epithelium metabolism of 7-ketocholesterol occurs by esterification to fatty acids via cPLA2alpha (zeige PLA2G4A ELISA Kits) and SOAT1 followed by selective efflux to HDL (zeige HSD11B1 ELISA Kits).
These studies demonstrate that both SIAE and SOAT activities seem to be responsible for the enhanced level of Neu5,9Ac(2) in lymphoblasts, which is a hallmark in acute lymphoblastic leukemia
the polymorphism of rs1044925 in the ACAT-1 gene is mainly associated with female serum total cholesterol, LDL-C and ApoB levels in the Bai Ku Yao population
These findings suggest the potential involvement of MAPK (zeige MAPK1 ELISA Kits) and STAT (zeige STAT1 ELISA Kits) pathways in norcantharidin-induced apoptogenesis.
SF-1 (zeige NR5A1 ELISA Kits)-dependent up-regulation of SOAT1 may be important for maintaining readily-releasable cholesterol reserves needed for active steroidogenesis and during episodes of recurrent stress.
Results show that signaling through ACAT/cholesterol esterification is a novel pathway for the CCK2R (zeige CCKBR ELISA Kits) that contributes to tumor cell proliferation and invasion.
polymorphism of the gene encoding acyl-coenzyme A: cholesterol acyltransferase 1 (SOAT1) is involved in the regulation of beta-amyloid peptide (zeige APP ELISA Kits) generation, is associated with low brain amyloid load and with low cerebrospinal fluid levels of cholesterol
a potential regulatory relationship between the sterol O-acetyltransferase 1 gene and Hoxc13 gene
Soat1 is a quantitative trait loci gene contributing to hyperlipidemia.
soat1 had an important role in normal hair formation
ACAT1 activity plays a central role in the proper trafficking of cholesterol and in cholesterol-sensing in the macrophage.
The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene.
sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
, sterol O-acyltransferase 1
, sterol O-acyltransferase 1-like
, sterol O-acyltransferase
, acyl-coenzyme A:cholesterol acyltransferase 1
, acyl coenzyme A:cholesterol acyltransferase 1
, adrenocortical lipid depletion
, cholesterol acyltransferase 1
, acyltransferase wax synthase
, Acyl-coenzyme A:cholesterol acyltransferase 1
, Cholesterol acyltransferase 1