Spastic Paraplegia 21 Proteine (SPG21)

The protein encoded by SPG21 was identified by a two-hybrid screen using CD4 as the bait. Zusätzlich bieten wir Ihnen SPG21 Antikörper (32) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SPG21 51324 Q9NZD8
SPG21 27965 Q9CQC8
SPG21 300791 Q5XIC4
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Top SPG21 Proteine auf antikoerper-online.de

Showing 10 out of 18 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Baculovirus infected Insect Cells Human GST tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$437.80
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Baculovirus infected Insect Cells Maus GST tag,His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$437.80
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,674.83
Details
Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,821.50
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,821.50
Details

SPG21 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

Weitere Proteine zu Spastic Paraplegia 21 (SPG21) Interaktionspartnern

Human Spastic Paraplegia 21 (SPG21) Interaktionspartner

  1. HBV X gene enhanced SPG21 gene promoter activity, SPG21 mRNA expression and SPG21 protein production in HepG2 cells in a dose-dependent manner.

  2. frameshift results in the premature termination of the encoded product, which is designated "maspardin" (Mast syndrome, spastic paraplegia, autosomal recessive with dementia)

  3. Data report that maspardin localizes prominently to cytoplasm as well as to membranes, possibly at trans-Golgi network/late endosomal compartments, and that maspardin interacts with the aldehyde dehydrogenase ALDH16A1 (zeige ALDH16A1 Proteine).

Mouse (Murine) Spastic Paraplegia 21 (SPG21) Interaktionspartner

  1. Study showed that the loss of maspardin attenuates the growth, maturation, and axonal branching of cortical neurons to promote progressive neuronal dysfunction; impairment of sensory motor neurons in SPG21-/- mice; and that SPG21-/- cortical neurons failed to respond to EGF (zeige EGF Proteine)-induced growth and maturation, which is confirmed by the attenuated expression of a subset of EGFR (zeige EGFR Proteine) target genes

  2. Mast syndrome gene SPG21 in mice has a role in hind limb function and axon branching in cultured cortical neurons

SPG21 Protein Überblick

Protein Überblick

The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Spastic Paraplegia 21 Proteine (SPG21)

  • SPG21, maspardin (SPG21)
  • SPG21, maspardin (Spg21)
  • spastic paraplegia 21 (autosomal recessive, Mast syndrome) (SPG21)
  • SPG21, maspardin S homeolog (spg21.S)
  • spastic paraplegia 21 (autosomal recessive, Mast syndrome) (spg21)
  • ACP33 Protein
  • BM-019 Protein
  • C78576 Protein
  • D9Wsu18e Protein
  • GL010 Protein
  • Maspardin Protein
  • MAST Protein
  • wu:fd07h02 Protein
  • zgc:73091 Protein

Bezeichner auf Proteinebene für Spastic Paraplegia 21 Proteine (SPG21)

acid cluster protein 33 , maspardin , spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog , spastic paraplegia 21 , spastic paraplegia 21 homolog , spastic paraplegia 21, maspardin (autosomal recessive, Mast syndrome) , spastic paraplegia 21 (autosomal recessive, Mast syndrome)

GENE ID SPEZIES
51324 Homo sapiens
404069 Bos taurus
100358285 Oryctolagus cuniculus
27965 Mus musculus
300791 Rattus norvegicus
415526 Gallus gallus
487599 Canis lupus familiaris
100514084 Sus scrofa
734314 Xenopus laevis
100174603 Pongo abelii
406704 Danio rerio
100713790 Cavia porcellus
Ausgewählte Anbieter für SPG21 Proteine (SPG21)
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