SUMO1 Activating Enzyme Subunit 1 Proteine (SAE1)

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. Zusätzlich bieten wir Ihnen SAE1 Antikörper (134) und SAE1 Kits (10) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SAE1 10055 Q9UBE0
SAE1 56459 Q9R1T2
Ratte SAE1 SAE1 308384 Q6AXQ0
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Top SAE1 Proteine auf antikoerper-online.de

Showing 10 out of 19 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Baculovirus infected Insect Cells Human GST tag,His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$554.07
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 15 bis 19 Tage
$319.00
Details
Hefe Xenopus laevis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,933.33
Details
Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,938.83
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,938.83
Details
Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,942.50
Details

SAE1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , , ,
Mouse (Murine)

Weitere Proteine zu SUMO1 Activating Enzyme Subunit 1 (SAE1) Interaktionspartnern

Human SUMO1 Activating Enzyme Subunit 1 (SAE1) Interaktionspartner

  1. the expression of SENP8 (zeige SENP8 Proteine), SAE1, PIAS1 (zeige PIAS1 Proteine), PIAS2 (zeige PIAS2 Proteine) and ZMIZ1 is deregulated in the majority of PTC (zeige F9 Proteine) tissues, likely contributing to the PTC (zeige F9 Proteine) phenotype.

  2. as it has been shown by flow cytometry analysis, specific knockdown of SAE1 slowed down the cell population at G0/G1 phase and induced apoptosis of RKO cells.

  3. Data indicate the role of anti-SUMO activating enzyme SAE1 and SAE2 (zeige RBBP8 Proteine) antibody as marker of dermatomyositis.

  4. Data show that the SAE2 (zeige RBBP8 Proteine) subunit of the small ubiquitin-like modifier (SUMO (zeige SUMO1 Proteine)) E1 is autoSUMOylated at residue Lys (zeige LYZ Proteine)-236, and SUMOylation was catalyzed by Ubc9 (zeige UBE2I Proteine) at several additional Lys (zeige LYZ Proteine) residues surrounding the catalytic Cys (zeige DNAJC5 Proteine)-173 of SAE2 (zeige RBBP8 Proteine).

  5. loss of SAE1/2 activity drives synthetic lethality with Myc (zeige MYC Proteine); inactivation of SAE2 (zeige RBBP8 Proteine) leads to mitotic catastrophe and cell death upon Myc (zeige MYC Proteine) hyperactivation; findings in Myc (zeige MYC Proteine)-high breast cancers suggest low tumor SAE1 and SAE2 (zeige RBBP8 Proteine) correlates metastasis-free survival

  6. The mammalian E1 subunits can be imported separately, identify nuclear localization signals (NLSs) in Aos1 and in Uba2, and demonstrate that their import is mediated by importin alpha/beta in vitro and in intact cells.

  7. structures of heterodimeric Sae1/Sae2 (zeige RBBP8 Proteine)-Mg.ATP and Sae1/Sae2 (zeige RBBP8 Proteine)-SUMO-1 (zeige SUMO1 Proteine)-Mg.ATP complexes

  8. SUMO-1 (zeige SUMO1 Proteine) controls the protein stability and the biological function of phosducin (zeige PDC Proteine).

Zebrafish SUMO1 Activating Enzyme Subunit 1 (SAE1) Interaktionspartner

  1. sae1 is essential for the maintenance of hematopoietic stem/progenitor cells during fetal hematopoiesis in zebrafish.

SAE1 Protein Überblick

Protein Überblick

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999

Genbezeichner und Symbole assoziert mit SAE1

  • SUMO1 activating enzyme subunit 1 (SAE1)
  • SUMO1 activating enzyme subunit 1 (Sae1)
  • SUMO1 activating enzyme subunit 1 L homeolog (sae1.L)
  • SUMO1 activating enzyme subunit 1 (sae1)
  • 2400010M20Rik Protein
  • 2610044L12Rik Protein
  • AL033372 Protein
  • aos Protein
  • AOS1 Protein
  • Aos1p Protein
  • AW743391 Protein
  • D7Ertd177e Protein
  • HSPC140 Protein
  • sae2a Protein
  • Sua1 Protein
  • Sua1p Protein
  • uble1a Protein
  • wu:fa28b04 Protein
  • zgc:86633 Protein

Bezeichner auf Proteinebene für SAE1

SUMO-1 activating enzyme E1 N subunit , SUMO-1 activating enzyme subunit 1 , SUMO-activating enzyme subunit 1 , activator of SUMO1 , sentrin/SUMO-activating protein AOS1 , ubiquitin-like 1-activating enzyme E1A , ubiquitin-like protein SUMO-1 activating enzyme , ubiquitin-like (sentrin) activating enzyme E1A , ubiquitin-like 1 (sentrin) activating enzyme E1A , ubiquitin-like 1 (sentrin) activating enzyme subunit 1 , SUMO-activating enzyme E1 N subunit , SUMO1 activating enzyme subunit 2a , Ubiquitin-like 1-activating enzyme E1A , fa28b04

GENE ID SPEZIES
10055 Homo sapiens
56459 Mus musculus
308384 Rattus norvegicus
476425 Canis lupus familiaris
505512 Bos taurus
100173973 Pongo abelii
443558 Xenopus laevis
100718649 Cavia porcellus
415148 Danio rerio
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