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SAE1 Produkte

(SUMO1 Activating Enzyme Subunit 1 (SAE1))

Kategorien

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].

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Ausgewählte SAE1 Kategorien

SAE1 Antikörper

High quality antibodies with extensive validation data.

SAE1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SAE1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SAE1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC, IP
Validierungen
  • (7)
Kat. Nr. ABIN2856922
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN564342
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN389081
Menge 400 μL
Datenblatt Datenblatt

Empfohlene SAE1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970456
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380924
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951062
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SAE1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125243
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319108
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3087825
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SAE1 Produkten

Kho, Lee, Jeong, Oh, Gorski, Fish, Sanchez, DeVita, Christensen, Dahl, Hajjar: "Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure." in: Nature communications, Vol. 6, pp. 7229, (2015) (PubMed).

Fujimoto, Matsushita, Hamaguchi, Kaji, Asano, Ogawa, Yamaoka, Fujikawa, Tsukada, Sato, Echigo, Hasegawa, Takehara: "Autoantibodies to small ubiquitin-like modifier activating enzymes in Japanese patients with dermatomyositis: comparison with a UK Caucasian cohort." in: Annals of the rheumatic diseases, Vol. 72, Issue 1, pp. 151-3, (2012) (PubMed).

Lois, Lima: "Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1." in: The EMBO journal, Vol. 24, Issue 3, pp. 439-51, (2005) (PubMed).

Desterro, Rodriguez, Kemp, Hay: "Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10618-24, (1999) (PubMed).

Norton, Atherton: "Coupling of cell growth control and apoptosis functions of Id proteins." in: Molecular and cellular biology, Vol. 18, Issue 4, pp. 2371-81, (1998) (PubMed).

Norton, Deed, Craggs, Sablitzky: "Id helix-loop-helix proteins in cell growth and differentiation." in: Trends in cell biology, Vol. 8, Issue 2, pp. 58-65, (1998) (PubMed).

Cooper, Brady, Bilia, Iscove, Quesenberry: "Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system." in: Blood, Vol. 89, Issue 9, pp. 3155-65, (1997) (PubMed).

Hara, Hall, Peters: "Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors." in: The EMBO journal, Vol. 16, Issue 2, pp. 332-42, (1997) (PubMed).

Langlands, Yin, Anand, Prochownik: "Differential interactions of Id proteins with basic-helix-loop-helix transcription factors." in: The Journal of biological chemistry, Vol. 272, Issue 32, pp. 19785-93, (1997) (PubMed).

Iavarone, Garg, Lasorella, Hsu, Israel: "The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein." in: Genes & development, Vol. 8, Issue 11, pp. 1270-84, (1994) (PubMed).

Synonyme und alternative Namen zu SAE1

SUMO1 activating enzyme subunit 1 (SAE1), SUMO1 activating enzyme subunit 1 (Sae1), SUMO1 activating enzyme subunit 1 L homeolog (sae1.L), SUMO1 activating enzyme subunit 1 (sae1), 2400010M20Rik, 2610044L12Rik, AL033372, aos, AOS1, Aos1p, AW743391, D7Ertd177e, HSPC140, sae2a, SUA1, Sua1, Sua1p, UBLE1A, Uble1a, uble1a, wu:fa28b04, zgc:86633

Bezeichner auf Proteinebene für SAE1

  • SUMO-1 activating enzyme E1 N subunit
  • SUMO-1 activating enzyme subunit 1
  • SUMO-activating enzyme subunit 1
  • activator of SUMO1
  • sentrin/SUMO-activating protein AOS1
  • ubiquitin-like 1-activating enzyme E1A
  • ubiquitin-like protein SUMO-1 activating enzyme
  • ubiquitin-like (sentrin) activating enzyme E1A
  • ubiquitin-like 1 (sentrin) activating enzyme E1A
  • ubiquitin-like 1 (sentrin) activating enzyme subunit 1
  • SUMO-activating enzyme E1 N subunit
  • SUMO1 activating enzyme subunit 2a
  • Ubiquitin-like 1-activating enzyme E1A
  • fa28b04
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