ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 1 Proteine (ST6GALNAC1)

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. Zusätzlich bieten wir Ihnen ST6GALNAC1 Antikörper (38) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ST6GALNAC1 55808 Q9NSC7
ST6GALNAC1 20445 Q9QZ39
Ratte ST6GALNAC1 ST6GALNAC1 287920  
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Showing 5 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,649.05
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$6,616.87
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Insektenzellen Human Unkonjugiert   5 μg Anmelden zum Anzeigen 2 bis 3 Tage
$175.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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ST6GALNAC1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)
,

Weitere Proteine zu ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 1 (ST6GALNAC1) Interaktionspartnern

Human ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 1 (ST6GALNAC1) Interaktionspartner

  1. Our results indicated that ST6GALNAC1 was downregulated in sporadic esophageal squamous cell carcinoma via hyper-methylation and loss of heterozygosity , and it may be a candidate responsible gene for esophageal squamous cell carcinoma

  2. ST6GalNAc I regulates the gene expression of IGF-1 (zeige IGF1 Proteine) through STAT5b (zeige STAT5B Proteine) activation and plays role in gastric cancer invasion and metastasis.

  3. upregulated Siat7A expression, which was paralleled by the increased Klf4 (zeige KLF4 Proteine) in the ischemic myocardium, contributed to cardiomyocyte apoptosis following myocardial infarction

  4. Using qRT-PCR, sialyl-Tn expression was found to be associated with an increase in alpha2,6-sialyltransferase gene (ST6GALNAC1) and a decrease in core 1 synthase gene (C1GALT1) in LS174T cells.

  5. It was confirmed that MUC1 (zeige MUC1 Proteine) carries sialyl Tn also in human advanced gastric cancer tissues

  6. Golgi N-glycosyltransferases beta-1,2-N-acetylglucosaminyltransferase I (zeige MGAT1 Proteine), beta-1,2-N-acetylglucosaminyltransferase II (zeige MGAT2 Proteine), 1,4-galactosyltransferase I (zeige B4GALT7 Proteine), and alpha-2,6-sialyltransferase (zeige ST6GAL2 Proteine) I form both homo- and heterodimeric enzyme complexes in live cells

  7. The stable transfection of MDA-MB-231 with an expression vector encoding ST6GalNAc I induces the expression of STn (zeige EEF1A2 Proteine) antigen at the cell surface.

  8. ST6GalNAc-I sialyltransferase localizes throughout the Golgi and has a role in synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer

  9. Expression of ppGalNAc-T6 is significantly higher in breast cancer compared to 'normal'/benign breast tissue samples. ST6GalNAc-I expression in breast cancer is associated with better prognosis.

Mouse (Murine) ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 1 (ST6GALNAC1) Interaktionspartner

  1. Results suggest a role of ST6GalNAc I in promoting the growth and invasion of hepatocarcinoma cells through regulating PI3K/AKT (zeige AKT1 Proteine)/NF-kappa B (zeige NFKB1 Proteine) signaling, and ST6GalNAc I might be a marker for the prognosis and therapy of hepatocarcinoma.

  2. It was confirmed that MUC1 (zeige MUC1 Proteine) carries sialyl Tn also in human advanced gastric cancer tissues

  3. ST6GalNAc I has a role in O-glycosylation of the integrin beta1 chain and integrin beta 1 (zeige ITGB1 Proteine)-mediated signalling

ST6GALNAC1 Protein Überblick

Protein Überblick

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999

Genbezeichner und Symbole assoziert mit ST6GALNAC1

  • ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (ST6GALNAC1)
  • ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (St6galnac1)
  • ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (St6galnac1)
  • HSY11339 Protein
  • Siat7A Protein
  • ST6GalNAcI Protein
  • STYI Protein

Bezeichner auf Proteinebene für ST6GALNAC1

SIAT7-A , ST6GalNAc I , ST6GalNAcI , alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 , alpha-N-acetylgalactosaminidealpha-2,6-sialyltransferase , galNAc alpha-2,6-sialyltransferase I , sialyltransferase 7A , GalNAc alpha-2, 6-sialyltransferase I, long form , sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) A , sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-beta-galactosyl-1,3)-N-acetyl galactosaminde alpha-2,6-sialyltransferase) A , alpha-2,6-sialyltransferase ST6GalNAc I

GENE ID SPEZIES
396168 Gallus gallus
55808 Homo sapiens
100049002 Canis lupus familiaris
20445 Mus musculus
287920 Rattus norvegicus
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