Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha Proteine (PCBD1)

PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. Zusätzlich bieten wir Ihnen PCBD1 Antikörper (52) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PCBD1 13180 P61458
PCBD1 5092 P61457
PCBD1 29700 P61459
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Top PCBD1 Proteine auf antikoerper-online.de

Showing 10 out of 16 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$522.50
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 8 bis 11 Tage
$504.90
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
Details
Hefe Human His tag 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$484.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,185.33
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,185.33
Details

PCBD1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , , ,
, ,
Rat (Rattus)

Weitere Proteine zu Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) Interaktionspartnern

Mouse (Murine) Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) Interaktionspartner

  1. DCoH acts as a cofactor for HNF1 that stabilizes the dimeric HNF1 complex.

  2. HNF1alpha (zeige HNF1A Proteine) binding kinetics may distinguish regulation by DCoH2 (zeige PCBD2 Proteine), under thermodynamic control, from regulation by DCoH, under kinetic control

Human Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) Interaktionspartner

  1. We provide the first genetic evidence that PCBD1 mutations can cause early-onset nonautoimmune diabetes with features similar to dominantly inherited HNF1A (zeige HNF1A Proteine)-diabetes.

  2. Coactivator of the HNFB1 (HNF1 homeobox B (zeige HNF1B Proteine))-mediated transcription is necessary for fine tuning ATPase Na+/K+ transporting gamma 1 polypeptide (FXYD2 (zeige FXYD2 Proteine)) transcription in the distal convoluted tubule

  3. Pcbd1 is a moonlighting protein that has dehydratase activity in addition to functioning as a cofactor which regulates HNF1alpha (zeige HNF1A Proteine).

  4. variants of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2 (zeige HNF1B Proteine)) and the dimerization cofactor of HNF-1 (DcoH/PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function

  5. Data reveal DCoH/HNF-1 alpha (zeige HNF1A Proteine) expression and transcriptional activity in human epidermal melanocytes in vitro and in situ and identified tyrosinase (zeige TYR Proteine), the key enzyme for pigmentation, as a new transcriptional target.

  6. Albumin (zeige ALB Proteine) colocalized together with its transcription factor PCD/DCoH/HNF-1alpha (zeige HNF1A Proteine) in suprabasal keratinocytes in human full-thickness skin sections and in keratinocytes cultured in serum-free medium.

  7. Properties of dehydratase/DCoHalpha are consistent with hypothesis that activity of this isozyme could account for relatively mild symptoms reported for patients with a defect in dehydratase/DCoH

PCBD1 Protein Überblick

Protein Überblick

This gene encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).

Genbezeichner und Symbole assoziert mit PCBD1

  • pterin-4a-carbinolamine dehydratase (Pcd)
  • pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (pcbd1)
  • pterin-4-alpha-carbinolamine dehydratase (Tb11.02.4890)
  • pterin-4-alpha-carbinolamine dehydratase (pcbd)
  • pterin-4-alpha-carbinolamine dehydratase (Fbal_2579)
  • pterin-4-alpha-carbinolamine dehydratase (Ftrac_2004)
  • pterin-4-alpha-carbinolamine dehydratase (Celal_2911)
  • pterin-4-alpha-carbinolamine dehydratase (Isop_1133)
  • pterin-4-alpha-carbinolamine dehydratase (Celly_0291)
  • pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 (Pcbd1)
  • pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha L homeolog (pcbd1.L)
  • pterin-4 alpha-carbinolamine dehydratase 1 (PCBD1)
  • pterin-4 alpha-carbinolamine dehydratase 1 (Pcbd1)
  • BcDNA:LP07248 Protein
  • CG1963 Protein
  • DCoH Protein
  • DDBDRAFT_0204977 Protein
  • DDBDRAFT_0305045 Protein
  • DDB_0204977 Protein
  • DDB_0305045 Protein
  • Dmel\\CG1963 Protein
  • PCBD Protein
  • pcd Protein
  • PHS Protein
  • TCF1 Protein
  • Xdcoh Protein
  • zgc:73389 Protein

Bezeichner auf Proteinebene für PCBD1

CG1963-PA , Pcd-PA , pterin-4-alpha-carbinolamine dehydratase , 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) , 4-alpha-hydroxy-tetrahydropterin dehydratase , PCD , PHS , dimerization cofactor of HNF1 , dimerization cofactor of hepatocyte nuclear factor 1-alpha , dimerization cofactor of hepatocyte nuclear factor-1-alpha , phenylalanine hydroxylase-stimulating protein , pterin carbinolamine dehydratase , DCoH , XDCoH , 6-pyruvoyl-tetrahydropterin synthase , cDcoH , pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) , dimerizing cofactor for HNF1 , pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1

GENE ID SPEZIES
43499 Drosophila melanogaster
393787 Danio rerio
496425 Xenopus (Silurana) tropicalis
3665797 Trypanosoma brucei brucei strain 927/4 GUTat10.1
8623790 Dictyostelium discoideum AX4
9771410 Ferrimonas balearica DSM 9799
10012150 Marivirga tractuosa DSM 4126
10145334 Cellulophaga algicola DSM 14237
10155246 Isosphaera pallida ATCC 43644
10262275 Cellulophaga lytica DSM 7489
13180 Mus musculus
397951 Xenopus laevis
395729 Gallus gallus
5092 Homo sapiens
530736 Bos taurus
29700 Rattus norvegicus
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