anti-Protein-O-Mannosyltransferase 2 (POMT2) Antikörper

The protein encoded by POMT2 is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. Zusätzlich bieten wir Ihnen POMT2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Gen	GeneID	UniProt
POMT2	29954	Q9UKY4
POMT2	217734	Q8BGQ4
POMT2	688673

Direkt bei antikoerper-online bestellen

+1 877 302 8632
+1 888 205 9894 (toll-free)
Online bestellen
orders@antikoerper-online.de

Top anti-POMT2 Antikörper auf antikoerper-online.de

Showing 10 out of 39 products:

Katalog Nr.	Reaktivität	Wirt	Konjugat	Applikation	Menge	Anbieter	Lieferzeit	Preis	Details
ABIN2782792	Rind (Kuh)	Kaninchen	Unkonjugiert	WB	100 μL	Anmelden zum Anzeigen	2 bis 3 Tage	$289.00	Details
ABIN2782791	Rind (Kuh)	Kaninchen	Unkonjugiert	WB	100 μL	Anmelden zum Anzeigen	2 bis 3 Tage	$289.00	Details
ABIN321181	Fledermaus	Kaninchen	Unkonjugiert	WB	50 μg	Anmelden zum Anzeigen	11 bis 14 Tage	$551.83	Details
ABIN321182	Fledermaus	Kaninchen	Unkonjugiert	WB	50 μg	Anmelden zum Anzeigen	11 bis 14 Tage	$551.83	Details
ABIN1537449	Human	Kaninchen	Unkonjugiert	WB	400 μL	Anmelden zum Anzeigen	10 bis 11 Tage	$385.00	Details
ABIN2747315	Human	Kaninchen	Unkonjugiert	ELISA, IHC, IP, WB	100 μg	Anmelden zum Anzeigen	1 bis 2 Tage	$462.69	Details
ABIN2459062	Human	Kaninchen	Unkonjugiert	ELISA, WB	50 μg	Anmelden zum Anzeigen	2 bis 3 Tage	$446.88	Details
ABIN635570	Human	Kaninchen	Unkonjugiert	WB	50 μg	Anmelden zum Anzeigen	9 bis 11 Tage	$473.93	Details
ABIN4892311	Human	Kaninchen	Unkonjugiert	WB	100 μL	Anmelden zum Anzeigen	8 bis 11 Tage	$488.73	Details
ABIN565444	Human	Maus	Unkonjugiert	ELISA, WB	100 μg	Anmelden zum Anzeigen	11 bis 12 Tage	$440.00	Details

Weitere Produktkategorien zu POMT2 Antikörper

Weitere Antikörper gegen POMT2 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Protein-O-Mannosyltransferase 2 (POMT2) Interaktionspartner

Study demonstrated that expression of RNA interference (RNAi) for the rt gene and the tw mutant was almost completely lethal and semi-lethal, respectively.
molecular cloning and characterization of POMT2
Drosophila POMT1 and POMT2 function as a protein O-mannosyltransferase in association with each other to generate and maintain normal muscle development.
establish a central role for Dystroglycan (Dg) in maintaining integrity in Drosophila larval muscles and demonstrate the importance of glycosylation to Dg function in Drosophila

Zebrafish Protein-O-Mannosyltransferase 2 (POMT2) Interaktionspartner

Protein O-mannosylation is necessary for normal embryonic development.

Human Protein-O-Mannosyltransferase 2 (POMT2) Interaktionspartner

Muscle biopsy revealed absent alpha-dystroglycan on immunostaining and genetic testing confirmed the diagnosis with two previously described POMT2 mutations. This is the first reported case of WWS syndrome associated with noncompaction cardiomyopathy
POMT2 missense mutation is associated with Cystic kidneys in fetal Walker-Warburg syndrome.
O-mannosylation of cadherins and protocadherins does not require POMT1 and/or POMT2 in contrast to alpha-dystroglycan, and moreover, the O-Man glycans on cadherins are not elongated.
Our report is the first to document an association between POMT2 mutations and aortopathy with concomitant depressed left ventricular systolic function.
the effects of replacing Arg(64), Glu(78) and Arg(138)residues in human POMT1 and POMT2 with Ala on complex formation and enzymatic activity were studied.
the function of the gene products is only known for POMT1, POMT2, and POMGnT1, all responsible for the O-mannosylglycan biosynthesis
the N-glycosylation of POMT1 and POMT2 is required for maintaining the conformation as well as the activity of the POMT1-POMT2 complex.
molecular cloning and characterization
active enzyme complex of POMT1 and POMT2 suggests that the regulation of protein O-mannosylation is complex and appears to be required for normal structure and function of alpha-dystroglycan in muscle and brain
POMT2 mutations cause alpha-dystroglycan hypoglycosylation and Walker-Warburg syndrome [case reports]
human protein O-mannosyltransferases 1 and 2 form heterocomplexes which possess protein O-mannosyltransferase activity
Several mutations were found in the Protein O-Mannosyltransferase 1 and 2 (POMT1 and POMT2) genes, and one mutation was found in each of the fukutin and fukutin-related protein (FKRP) genes.
Our results broaden the clinical spectrum associated with POMT2 mutations, which should be considered in patients with CMD associated with microcephaly, and severe mental retardation with or without ocular involvement.
identified a POMT2 homozygous missense mutation in a girl with a mild limb-girdle muscular dystrophy (LGMD) phenotype
testis POMT2 is highly conserved among mammals, including humans, suggesting a crucial function that is distinct from somatic POMT2
In pomt2 mutation in CMD patient(three out of 5) show cerebellar hypoplasia.
Our results indicate that mutations in POMT2 can cause a wide spectrum of clinical phenotypes as observed in other genes associated with alpha-dystroglycanopathy.
POMT2 intragenic deletions and splicing abnormalities causing congenital muscular dystrophy with mental retardation are reported.

Mouse (Murine) Protein-O-Mannosyltransferase 2 (POMT2) Interaktionspartner

Data show that POMT2 deletion in the meninges did not disrupt the development of the neocortex, and suggest that normal brain development requires protein O-mannosylation activity in neural tissue but not the meninges.
molecular cloning and characterization
testis POMT2 is highly conserved among mammals, including humans, suggesting a crucial function that is distinct from somatic POMT2

POMT2 Antigen-Profil

Protein Überblick

The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS).

Genbezeichner und Symbole assoziert mit POMT2

twisted (tw) Antikörper
protein O-mannosyltransferase 2 (POMT2) Antikörper
protein-O-mannosyltransferase 2 (pomt2) Antikörper
protein O-mannosyltransferase 2 (pomt2) Antikörper
protein-O-mannosyltransferase 2 (Pomt2) Antikörper

A830009D15Rik Antikörper
AW046274 Antikörper
CG12311 Antikörper
Dmel\\CG12311 Antikörper
DmPOMT2 Antikörper
dPOMT2 Antikörper
EG:34F3.7 Antikörper
im:7153045 Antikörper
LGMD2N Antikörper
MDDGA2 Antikörper
MDDGB2 Antikörper
MDDGC2 Antikörper
Pomt2 Antikörper
zgc:158749 Antikörper
zPOMT2 Antikörper

Bezeichner auf Proteinebene für POMT2

CG12311-PA , CG12311-PB , protein O-mannosyltransferase 2 , tricky-dickey , tw-PA , tw-PB , twisted , putative protein O-mannosyltransferase , protein-O-mannosyltransferase 2 , protein O-mannosyl-transferase 2 , protein O-mannosyl-transferase 2-like , dolichyl-phosphate-mannose--protein mannosyltransferase 2

GENE ID	SPEZIES
31024	Drosophila melanogaster
453067	Pan troglodytes
480400	Canis lupus familiaris
705604	Macaca mulatta
100022191	Monodelphis domestica
100155173	Sus scrofa
100400916	Callithrix jacchus
100437813	Pongo abelii
100490100	Xenopus (Silurana) tropicalis
100566915	Anolis carolinensis
563878	Danio rerio
423373	Gallus gallus
29954	Homo sapiens
537054	Bos taurus
217734	Mus musculus
688673	Rattus norvegicus

Ausgewählte Anbieter für anti-POMT2 (POMT2) Antikörper

Haben Sie etwas anderes gesucht?

Telefon:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antikoerper-online.de