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The protein encoded by PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen PTPN7 Antikörper (105) und viele weitere Produktgruppen zu diesem Protein an.
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structure of the protein tyrosine phosphatase (zeige ACP1 Proteine) catalytic domain of HePTP, residues 44-339
determined high-resolution structures of all of the human family members of Mitogen-Activated Protein Kinase (zeige MAPK1 Proteine)-specific protein tyrosine phosphatases
PTPN7 as a negative regulator of TNF-alpha (zeige TNF Proteine) expression and the inflammatory response in macrophages
beta(2)AR stimulation on a B cell phosphorylates and inactivates HePTP in a Gs/cAMP/PKA-dependent manner to release bound p38 MAPK (zeige MAPK14 Proteine), making more available for phosphorylation and subsequent IgE regulation.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.
dual specificity phosphatase 1
, hematopoietic protein-tyrosine phosphatase
, protein-tyrosine phosphatase LC-PTP
, protein-tyrosine phosphatase, nonreceptor-type, stress induced
, tyrosine-protein phosphatase non-receptor type 7
, protein-tyrosine phosphatase, non-receptor type 7