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PRMT1 encodes a member of the protein arginine N-methyltransferase (PRMT) family. Zusätzlich bieten wir Ihnen PRMT1 Proteine (31) und und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 146 products:
Human Polyclonal PRMT1 Primary Antibody für IHC (p), IP - ABIN151674
Fisk, Zurita-Lopez, Sayegh, Tomasello, Clarke, Read: TbPRMT6 is a type I protein arginine methyltransferase that contributes to cytokinesis in Trypanosoma brucei. in Eukaryotic cell 2010
Important roles of PRMT1 in progression of gastric cancer. Given the dual functions of PRMT1, it is as a potential drug target of gastric cancer with extreme caution.
Mitochondrial Ca(2 (zeige CA2 Antikörper)+) uptake is controlled by protein arginine methyl transferase 1 that asymmetrically methylates MICU1 (zeige MICU1 Antikörper), resulting in decreased Ca(2 (zeige CA2 Antikörper)+) sensitivity. UCP2 (zeige UCP2 Antikörper)/3 normalize Ca(2 (zeige CA2 Antikörper)+) sensitivity of methylated MICU1 (zeige MICU1 Antikörper) and, thus, re-establish mitochondrial Ca(2 (zeige CA2 Antikörper)+) uptake activity.
High-PRMT1 expression is associated with resistance to cetuximab in triple-negative breast cancer.
a significant role for PRMT1 in HCC (zeige FAM126A Antikörper) progression and metastasis in vitro and in vivo via STAT3 (zeige STAT3 Antikörper) signalling pathway activation. PRMT1 may be a potential novel prognostic biomarker and new therapeutic target for hepatocellular carcinoma.
High PRMT1 expression is associated with head and neck and oral cancer.
TRIM48 Promotes ASK1 (zeige MAP3K5 Antikörper) Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1 (zeige MAP3K5 Antikörper)-Negative Regulator PRMT1
data collectively suggest that silencing of PRMT1 exerts anti-catabolic and anti-inflammatory effects on IL-1beta (zeige IL1B Antikörper)-induced chondrocytes via suppressing the Gli-1 (zeige GLI1 Antikörper) mediated Hedgehog (zeige SHH Antikörper) signaling pathway, indicating that PRMT1 plays a critical role in OA development and serves as a promising therapeutic target for OA.
Deacetylation on both K200 and K205 by Sirtuin 1 (Sirt1 (zeige SIRT1 Antikörper)) and acetylation of p300 (EP300 (zeige EP300 Antikörper)) on K205 collaboratively prepare the motif for SCF (zeige KITLG Antikörper)(Fbxl17 (zeige FBXL17 Antikörper)) binding thereby triggering PRMT1 protein degradation.
PRMT1 has a role in regulating MYCN (zeige MYCN Antikörper) in neuroblastoma (zeige ARHGEF16 Antikörper)
Analysis of deletion constructs of SERBP1 (zeige SERBP1 Antikörper) showed that the C-terminal third of the SERBP1 (zeige SERBP1 Antikörper) protein, which contains one of its two substrate sites for protein arginine N-methyltransferase 1 (PRMT1), is necessary and sufficient for it to interact with RACK1 (zeige GNB2L1 Antikörper)
prmt8 (zeige PRMT8 Antikörper) may play important roles non-overlapping with prmt1 in embryonic and neural development depending on its specific N-terminus.
prmt1 gene is actively and ubiquitously expressed at both RNA and protein levels at the early developmental stages of zebrafish.
PRMT1 functions transiently as a coactivator in thyroid hormone (zeige PTH Antikörper) (T3) receptor (TR)-mediated transcription by enhancing TR-T3 response element binding and further suggest that PRMT1 has tissue-specific roles in regulating the rate of metamorphosis.
Results suggest that part of the type I arginine methyltransferases in brains, mainly PRMT1, are sequestered in an inactive form as they associated with membranes or large subcellular complexes.
the present study increases our understanding of PRMT1, -4, and -5 biology during the plasticity of skeletal muscle development. Our results provide evidence for a role of PRMT1, via a mitochondrially mediated mechanism, in driving the muscle differentiation program.
lipotoxicity-induced PRMT1 expression promotes endoplasmic reticulum stress-mediated mesangial cell apoptosis.
PRMT1 is an arginine methyltransferase involved in a variety of cell functions. Here the authors delete PRMT1 specifically in mature B cells to show the importance of arginine methylation for B cell proliferation, differentiation and survival, and thereby for humoral immunity.
Collectively, this study firstly demonstrated that PRMT1 exert podocyte-injury effects in mouse glomerulus through Ang (zeige ANG Antikörper) /ERK (zeige EPHB2 Antikörper) pathway, which reveals a potential therapeutic target for DN.
PRMT1 inhibition prevents gastric cancer progression by downregulating eIF4E (zeige EIF4E Antikörper) and targeting type II PRMT5 (zeige PRMT5 Antikörper).
Low Prmt1 expression is associated with osteosarcoma.
Collectively, the authors propose that Prmt1-dependent facilitation of KCNQ (zeige KCNQ1 Antikörper)-phosphatidylinositol-4,5-bisphosphate interaction underlies the positive regulation of KCNQ (zeige KCNQ1 Antikörper) activity by arginine methylation, which may serve as a key target for prevention of neuronal hyperexcitability and seizures.
Results identify a key molecular mechanism by which the BTG2 (zeige BTG2 Antikörper)-PRMT1 module regulates pre-B cell differentiation and inhibits pre-B cell leukemogenesis.
Data, including data from studies in cells from knockout mice, suggest that Prmt1 activity was necessary for c-Myc (zeige MYC Antikörper) binding to acetyltransferase p300 (zeige NOTCH1 Antikörper) in myeloid cells; Prmt1 inhibition decreases p300 (zeige NOTCH1 Antikörper) recruitment to c-Myc (zeige MYC Antikörper) target promoters and increased Hdac1 (zeige HDAC1 Antikörper) recruitment. [Prmt1, protein arginine N-methyltransferase 1; c-Myc (zeige MYC Antikörper) = Proto-Oncogene (zeige RAB1A Antikörper) Proteins c-myc (zeige MYC Antikörper); Hdac1 (zeige HDAC1 Antikörper) = histone deacetylase 1 (zeige HDAC1 Antikörper)]
PRMT1-dependent regulation of macrophage PPARgamma (zeige PPARG Antikörper) expression contributes to the infection susceptibility in PRMT1 knock-out mice
This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
protein arginine N-methyltransferase 1
, protein arginine methyltransferase 1
, protein arginine N-methyltransferase
, HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2
, heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2
, histone-arginine N-methyltransferase PRMT1
, interferon receptor 1-bound protein 4
, HMT1 hnRNP methyltransferase-like 2
, histone-arginine N-methyltransferase PRMT1-A
, protein arginine N-methyltransferase 1-A
, heterogeneous nuclear ribonucleoproteins methyltransferase-like 2
, arginine N-methyltransferase 1