Poly-U Binding Splicing Factor 60KDa Proteine (PUF60)

PUF60 encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. Zusätzlich bieten wir Ihnen PUF60 Antikörper (143) und PUF60 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PUF60 22827 Q9UHX1
PUF60 67959 Q3UEB3
PUF60 84401  
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Top PUF60 Proteine auf antikoerper-online.de

Showing 6 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human PUF60 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$668.03
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,617.17
Details

PUF60 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Am meisten referenzierte PUF60 Proteine

  1. Human PUF60 Protein expressed in HEK-293 Cells - ABIN2730160 : Fiorentino, Presby, Baer, Petri, Rieger, Soloski, Rosen, Mammen, Christopher-Stine, Casciola-Rosen: PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome. in Annals of the rheumatic diseases 2016 (PubMed)

Weitere Proteine zu Poly-U Binding Splicing Factor 60KDa (PUF60) Interaktionspartnern

Human Poly-U Binding Splicing Factor 60KDa (PUF60) Interaktionspartner

  1. Anti-PUF60 antibodies were nonspecific for myositis, since they could be detected in other rheumatic diseases.

  2. Authors report the identification of 25 DNVs out of which five were classified as pathogenic or likely pathogenic. A two base pair deletion was identified in the PUF60 gene. Result adds to the growing evidence that PUF60 is responsible for the majority of the symptoms reported for carriers of a microdeletion across this region.

  3. The present report describes a de novo missense mutation in PUF60, detected in a boy with multiple congenital anomalies.

  4. PUF60 auto-antibodies are detected in the sera of early-stage colon cancer patients and level decreases after surgery.

  5. These results confirm that PUF60 is a major driver for the developmental, craniofacial, skeletal and cardiac phenotypes associated with the 8q24.3 microdeletion

  6. Heterozygote loss-of-function variants in PUF60 cause a phenotype comprising growth/developmental delay and craniofacial, cardiac, renal, ocular and spinal anomalies.

  7. Mutations in PUF60 gene is associated with idiopathic hypereosinophilic syndrome.

  8. Concomitant over expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer cells.

  9. Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma.

  10. High FBP-interacting repressor expression is associated with hepatocellular carcinoma.

Zebrafish Poly-U Binding Splicing Factor 60KDa (PUF60) Interaktionspartner

  1. Suppression of scrib (zeige SCRIB Proteine) and puf60 in zebrafish leads to reduction in body length, small head size, and craniofacial defects.

PUF60 Protein Überblick

Protein Überblick

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit PUF60

  • poly(U) binding splicing factor 60 (PUF60)
  • poly-U binding splicing factor a (puf60a)
  • poly-U binding splicing factor 60 (Puf60)
  • poly(U) binding splicing factor 60 (Puf60)
  • 2410104I19Rik Protein
  • 2810454F19Rik Protein
  • fc21a05 Protein
  • FIR Protein
  • RoBPI Protein
  • Siahbp1 Protein
  • wu:fc21a05 Protein
  • wu:fi43a08 Protein

Bezeichner auf Proteinebene für PUF60

FBP interacting repressor , FUSE-binding protein-interacting repressor , Ro ribonucleoprotein-binding protein 1 , Siah binding protein 1 , poly(U)-binding-splicing factor PUF60 , pyrimidine tract binding splicing factor , 60 kDa poly(U)-binding-splicing factor , fuse-binding protein-interacting repressor , RNA-binding protein Siah-BP , poly-U binding splicing factor 60K , siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1 , siah-binding protein 1 , LOW QUALITY PROTEIN: poly(U)-binding-splicing factor PUF60 , poly(U) binding splicing factor 60KDa

GENE ID SPEZIES
22827 Homo sapiens
562370 Danio rerio
67959 Mus musculus
84401 Rattus norvegicus
607245 Canis lupus familiaris
512824 Bos taurus
100174042 Pongo abelii
100734967 Cavia porcellus
426402 Gallus gallus
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