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PUF60 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

PUF60 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2730160
  • Target Alle PUF60 Proteine anzeigen
    PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 6
    • 1
    • 1
    Human
    Quelle
    • 3
    • 3
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses PUF60 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human PUF60 / SIAHBP1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PUF60 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Fiorentino, Presby, Baer, Petri, Rieger, Soloski, Rosen, Mammen, Christopher-Stine, Casciola-Rosen: "PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome." in: Annals of the rheumatic diseases, Vol. 75, Issue 6, pp. 1145-51, (2016) (PubMed).

  • Target
    PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
    Andere Bezeichnung
    Puf60,siahbp1 (PUF60 Produkte)
    Synonyme
    FIR Protein, RoBPI Protein, SIAHBP1 Protein, fc21a05 Protein, wu:fc21a05 Protein, wu:fi43a08 Protein, 2410104I19Rik Protein, 2810454F19Rik Protein, Siahbp1 Protein, fe37c05 Protein, repressor Protein, si:ch211-12p8.2 Protein, si:zc12p8.2 Protein, wu:fb33e11 Protein, wu:fe37c05 Protein, zgc:86806 Protein, poly(U) binding splicing factor 60 Protein, poly-U binding splicing factor a Protein, poly-U binding splicing factor 60 Protein, poly-U binding splicing factor b Protein, PUF60 Protein, puf60a Protein, Puf60 Protein, puf60b Protein
    Hintergrund
    This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
    Molekulargewicht
    59.7 kDa
    NCBI Accession
    NP_510965
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