Multimerin 1 Proteine (MMRN1)

Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. Zusätzlich bieten wir Ihnen Multimerin 1 Antikörper (64) und Multimerin 1 Kits (24) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MMRN1 70945 B2RPV6
MMRN1 22915 Q13201
MMRN1 500152  
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Top Multimerin 1 Proteine auf antikoerper-online.de

Showing 5 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$720.00
Details
Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$768.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

MMRN1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
,
Rat (Rattus)

Am meisten referenzierte Multimerin 1 Proteine

  1. Human Multimerin 1 Protein expressed in Wheat germ - ABIN1311094 : Satoh, Hirayama, Takano, Suzuki-Inoue, Sato, Ohta, Nakagomi, Ozaki: VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets. in Thrombosis journal 2014 (PubMed)

Weitere Proteine zu Multimerin 1 (MMRN1) Interaktionspartnern

Mouse (Murine) Multimerin 1 (MMRN1) Interaktionspartner

  1. C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes, have an altered bone phenotype.

  2. Our data suggest that multimerin 1 supports platelet adhesive functions and thrombus formation, which will be important to verify by generating and testing selective multimerin 1 deficient mice.

Human Multimerin 1 (MMRN1) Interaktionspartner

  1. VWF binding to MMRN1 was enhanced by shear exposure and ristocetin, and required VWF A1A2A3 region, specifically the A1 and A3 domains.

  2. Lower levels of anti-elastin are related to CAD [ coronary artery disease ]

  3. our studies identify MMRN1 expression as a novel biomarker that may refine acute myelogenous leukemia risk stratification.

  4. multimerin 1 has a role in delivering and localizing factor V onto platelets prior to prothrombinase assembly

  5. disulfide-linked complexes of multimerin and factor V in platelets could be important for modulating the function of platelet factor V and its delivery onto activated platelets

  6. MMRN1 is a ligand for alphaIIbbeta3 and alphavbeta3

  7. The MMRN1 binding site was located in Factor V.

  8. Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin generation.

  9. MMRN1 supported the adhesion of activated, but not resting, washed platelets over a wide range of shear rates

Multimerin 1 (MMRN1) Protein Überblick

Protein Überblick

Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.

Genbezeichner und Symbole assoziert mit Multimerin 1 Proteine (MMRN1)

  • multimerin 1 (MMRN1)
  • multimerin 1 (mmrn1)
  • multimerin 1 (Mmrn1)
  • 4921530G03Rik Protein
  • ECM Protein
  • EMILIN4 Protein
  • GPIa* Protein
  • MMRN Protein
  • MMRN1 Protein

Bezeichner auf Proteinebene für Multimerin 1 Proteine (MMRN1)

multimerin 1 , multimerin-1 , multimerin-1-like , EMILIN-4 , elastin microfibril interface located protein 4 , elastin microfibril interfacer 4 , endothelial cell multimerin , glycoprotein Ia*

GENE ID SPEZIES
461376 Pan troglodytes
487858 Canis lupus familiaris
516574 Bos taurus
100053317 Equus caballus
100405446 Callithrix jacchus
100479479 Ailuropoda melanoleuca
100540990 Meleagris gallopavo
100551936 Anolis carolinensis
100601219 Nomascus leucogenys
70945 Mus musculus
22915 Homo sapiens
500152 Rattus norvegicus
100516922 Sus scrofa
428741 Gallus gallus
100357410 Oryctolagus cuniculus
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