anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) Antikörper

LGI1 is rearranged as a result of translocations in glioblastoma cell lines. Zusätzlich bieten wir Ihnen Leucine-Rich, Glioma Inactivated 1 Proteine (5) und Leucine-Rich, Glioma Inactivated 1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LGI1 9211 O95970
LGI1 56839 Q9JIA1
LGI1 252892 Q8K4Y5
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Top anti-Leucine-Rich, Glioma Inactivated 1 Antikörper auf antikoerper-online.de

Showing 10 out of 83 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-LGI1 Antibody Titration: 1.0 ug/ml Positive Control: HCT15 Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 7.5% SDS PAGE antibody diluted at 1:5000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert WB Western Blot: Lgi1 Antibody [NBP1-33087] - Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE, antibody diluted at 1:5000. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
Details
Human Maus HRP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Junction, Golgi Apparatus, Endoplasmic Reticulum. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) LGI1 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~60 kDa LGI1 protein using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Load: 10 µg. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~60 kDa. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$422.40
Details
Human Maus FITC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Junction, Golgi Apparatus, Endoplasmic Reticulum. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) LGI1 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~60 kDa LGI1 protein using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Load: 10 µg. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~60 kDa. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$426.80
Details
Human Maus Alkaline Phosphatase (AP) ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Junction, Golgi Apparatus, Endoplasmic Reticulum. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) LGI1 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~60 kDa LGI1 protein using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Load: 10 µg. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~60 kDa. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$429.00
Details
Human Maus Biotin ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Junction, Golgi Apparatus, Endoplasmic Reticulum. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) LGI1 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~60 kDa LGI1 protein using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Load: 10 µg. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~60 kDa. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$431.20
Details
Human Maus PE ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Junction, Golgi Apparatus, Endoplasmic Reticulum. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) LGI1 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~60 kDa LGI1 protein using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Load: 10 µg. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~60 kDa. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$432.30
Details

LGI1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Leucine-Rich, Glioma Inactivated 1 Antikörper

  1. Human Polyclonal LGI1 Primary Antibody für IHC, ELISA - ABIN1002722 : Gu, Gibert, Wirth, Elischer, Bloch, Meyer, Steinlein, Begemann: Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders. in Molecular biology and evolution 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal LGI1 Primary Antibody für ELISA, WB - ABIN1002723 : Chernova, Somerville, Cowell: A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors. in Oncogene 1999 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen Leucine-Rich, Glioma Inactivated 1 Interaktionspartner

Human Leucine-Rich, Glioma Inactivated 1 (LGI1) Interaktionspartner

  1. The clinical phenotypes of anti-LGI1 encephalitis and anti-Caspr2 (zeige CNTNAP2 Antikörper) encephalitis have been described in more detail including data on treatment and long-term follow-up. Lumping patients with anti-LGI1, anti-Caspr2 (zeige CNTNAP2 Antikörper) antibodies or lacking both, should be considered obsolete--{REVIEW}

  2. these results support the existence of a second mechanism, alternative to inhibition of protein secretion, by which ADLTE-causing LGI1 mutations exert their loss-of-function effect extracellularly, and suggest that interactions of LGI1 with both ADAM22 (zeige ADAM22 Antikörper) and ADAM23 (zeige Adam23 Antikörper) play an important role in the molecular mechanisms leading to utosomal dominant lateral temporal epilepsy

  3. Autosomal dominant epilepsy with auditory features family due to a novel LGI1 mutation.

  4. Clinical analysis of a lateral temporal lobe epilepsy cohort from Turkey and genetic contribution of LGI1 to autosomal dominant lateral temporal lobe epilepsy phenotype

  5. Report of three novel LGI1 mutations, a microdeletion of exon 2 and two missense mutations in exon 8, occurring in two autosomal dominant lateral temporal epilepsy families and in one sporadic patient with lateral temporal epilepsy

  6. study found no cryptic imbalances were in LGI1 in partial epilepsy with auditory features (PEAF) patients, suggesting that LGI1 microdeletions are not a frequent cause of PEAF

  7. The Multiplex ligation-dependent probe amplifications analysis did not reveal any pathogenic changes in the LGI1 gene. Chromosomal rearrangements involving the LGI1 gene were not identified in our series of familial or sporadic LTE (zeige SLC12A4 Antikörper).

  8. A new LGI1 missense mutation is identified in a large Korean family with autosomal dominant lateral temporal lobe epilepsy.

  9. Seven LGI1-affected individuals report auditory aura (zeige AURKA Antikörper) and one visual aura (zeige AURKA Antikörper); three families with autosomal dominant epilepsy and auditory features have novel LGI1 mutations.

  10. Downregulation of LGI1 promotes tumor metastasis in esophageal squamous cell carcinoma.

Mouse (Murine) Leucine-Rich, Glioma Inactivated 1 (LGI1) Interaktionspartner

  1. LGI1 has a role in regulating cortical development, which is increasingly becoming recognized as one of the causes of idiopathic epilepsy.

  2. LGI1 and ADAM22 (zeige ADAM22 Antikörper) form an essential synaptic organizing complex that coordinates the maturation of excitatory synapses by regulating the functional incorporation of PSD-95 (zeige DLG4 Antikörper)

  3. Review article demonstrating that LGI1 may be an essential player in the development of the brain

  4. Glutamatergic neuron-targeted loss of Lgi1 causes a severe epileptic phenotype; Lgi1 displays an essential role in brain during the whole life.

  5. Lgi1 contains nuclear localization signal that mediates Lgi1 localization to cytoplasm and nucleus in CNS embryonic neurons.

  6. This study demonistrated that LGI1 plays a critical role in both dendritic and axonal pruning, we identify a novel molecular pathway in synapse and circuit remodeling.

  7. Lgi1 may have a role in establishing normal brain architecture and neuronal functions during brain development suggesting that it may be involved in neurogenesis and neuronal plasticity

  8. LGI1(+/-) and LGI1(-/-) mice may provide useful models for lateral temporal lobe epilepsy, and more generally idiopathic focal epilepsy.

  9. Lgi1 null mutant mice exhibit myoclonic seizures and CA1 (zeige CA1 Antikörper) neuronal hyperexcitability.

  10. in the brain of C57BL/6J adult mice by in situ hybridization. We found that the LGI1 transcript is mainly expressed in the dentate gyrus and CA3 (zeige CA3 Antikörper) field of the hippocampus.

Leucine-Rich, Glioma Inactivated 1 (LGI1) Antigen-Profil

Protein Überblick

This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.

Genbezeichner und Symbole assoziert mit LGI1

  • leucine rich glioma inactivated 1 (LGI1) Antikörper
  • leucine-rich repeat LGI family, member 1 (Lgi1) Antikörper
  • leucine-rich, glioma inactivated 1 (Lgi1) Antikörper
  • leucine-rich, glioma inactivated 1 (LGI1) Antikörper
  • leucine-rich, glioma inactivated 1 (lgi1) Antikörper
  • leucine rich glioma inactivated 1 (Lgi1) Antikörper
  • ADLTE Antikörper
  • ADPAEF Antikörper
  • ADPEAF Antikörper
  • BB130740 Antikörper
  • EPITEMPIN Antikörper
  • EPT Antikörper
  • ETL1 Antikörper
  • IB1099 Antikörper
  • MGC146600 Antikörper

Bezeichner auf Proteinebene für LGI1

epitempin-1 , leucine-rich glioma-inactivated protein 1 , leucine-rich, glioma inactivated 1 , leucine-rich repeat LGI family, member 1 , putative leucine-rich glioma inactivated 1 , polymorphic marker clone YB07 , leucine-rich glioma-inactivated protein 1-like

GENE ID SPEZIES
9211 Homo sapiens
56839 Mus musculus
252892 Rattus norvegicus
423802 Gallus gallus
450619 Pan troglodytes
477777 Canis lupus familiaris
617080 Bos taurus
700520 Macaca mulatta
779819 Xenopus (Silurana) tropicalis
100172937 Pongo abelii
100219007 Taeniopygia guttata
100415038 Callithrix jacchus
100597927 Nomascus leucogenys
100726518 Cavia porcellus
100344253 Oryctolagus cuniculus
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