anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) Antikörper

LGI1 is rearranged as a result of translocations in glioblastoma cell lines. Zusätzlich bieten wir Ihnen Leucine-Rich, Glioma Inactivated 1 Proteine (5) und Leucine-Rich, Glioma Inactivated 1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LGI1 9211 O95970
LGI1 56839 Q9JIA1
LGI1 252892 Q8K4Y5
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Leucine-Rich, Glioma Inactivated 1 Antikörper auf antikoerper-online.de

Showing 10 out of 131 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-LGI1 Antibody Titration: 1.0 ug/ml Positive Control: HCT15 Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 7.5% SDS PAGE antibody diluted at 1:5000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert WB Western Blot: Lgi1 Antibody [NBP1-33087] - Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE, antibody diluted at 1:5000. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$516.98
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 4 bis 8 Tage
$522.50
Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 4 bis 8 Tage
$522.50
Details
Human Maus HRP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Junction, Golgi Apparatus, Endoplasmic Reticulum. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) LGI1 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~60 kDa LGI1 protein using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Load: 10 µg. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~60 kDa. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
$499.20
Details
Human Maus FITC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Junction, Golgi Apparatus, Endoplasmic Reticulum. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) LGI1 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~60 kDa LGI1 protein using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Load: 10 µg. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~60 kDa. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
$504.40
Details
Human Maus Alkaline Phosphatase (AP) ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Junction, Golgi Apparatus, Endoplasmic Reticulum. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) LGI1 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~60 kDa LGI1 protein using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Load: 10 µg. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~60 kDa. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
$507.00
Details
Human Maus Biotin ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Junction, Golgi Apparatus, Endoplasmic Reticulum. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) LGI1 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~60 kDa LGI1 protein using Mouse Anti-LGI1 Monoclonal Antibody, Clone S283-7 . Load: 10 µg. Primary Antibody: Mouse Anti-LGI1 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~60 kDa. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
$509.60
Details

Am meisten referenzierte anti-Leucine-Rich, Glioma Inactivated 1 Antikörper

  1. Human Polyclonal LGI1 Primary Antibody für IHC, ELISA - ABIN1002722 : Gu, Gibert, Wirth, Elischer, Bloch, Meyer, Steinlein, Begemann: Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders. in Molecular biology and evolution 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal LGI1 Primary Antibody für ELISA, WB - ABIN1002723 : Chernova, Somerville, Cowell: A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors. in Oncogene 1999 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal LGI1 Primary Antibody für IHC (p), WB - ABIN541687 : Fukata, Adesnik, Iwanaga, Bredt, Nicoll, Fukata: Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission. in Science (New York, N.Y.) 2006 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal LGI1 Primary Antibody für WB - ABIN541698 : Fialka, Gruber, Hitt, Opitz, Brunner, Schliephake, Kramer: CPA6, FMO2, LGI1, SIAT1 and TNC are differentially expressed in early- and late-stage oral squamous cell carcinoma--a pilot study. in Oral oncology 2008 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen Leucine-Rich, Glioma Inactivated 1 Interaktionspartner

Human Leucine-Rich, Glioma Inactivated 1 (LGI1) Interaktionspartner

  1. the LGI1-ADAM22 complex functions as the trans-synaptic machinery for precise synaptic transmission

  2. The data obtained strongly suggest the possibility of gene LGL1 inactivation by epigenetic mechanism: modified <>.

  3. The clinical phenotypes of anti-LGI1 encephalitis and anti-Caspr2 encephalitis have been described in more detail including data on treatment and long-term follow-up. Lumping patients with anti-LGI1, anti-Caspr2 antibodies or lacking both, should be considered obsolete--{REVIEW}

  4. these results support the existence of a second mechanism, alternative to inhibition of protein secretion, by which ADLTE-causing LGI1 mutations exert their loss-of-function effect extracellularly, and suggest that interactions of LGI1 with both ADAM22 and ADAM23 play an important role in the molecular mechanisms leading to utosomal dominant lateral temporal epilepsy

  5. Autosomal dominant epilepsy with auditory features family due to a novel LGI1 mutation.

  6. Clinical analysis of a lateral temporal lobe epilepsy cohort from Turkey and genetic contribution of LGI1 to autosomal dominant lateral temporal lobe epilepsy phenotype

  7. Report of three novel LGI1 mutations, a microdeletion of exon 2 and two missense mutations in exon 8, occurring in two autosomal dominant lateral temporal epilepsy families and in one sporadic patient with lateral temporal epilepsy

  8. study found no cryptic imbalances were in LGI1 in partial epilepsy with auditory features (PEAF) patients, suggesting that LGI1 microdeletions are not a frequent cause of PEAF

  9. The Multiplex ligation-dependent probe amplifications analysis did not reveal any pathogenic changes in the LGI1 gene. Chromosomal rearrangements involving the LGI1 gene were not identified in our series of familial or sporadic LTE.

  10. A new LGI1 missense mutation is identified in a large Korean family with autosomal dominant lateral temporal lobe epilepsy.

  11. Seven LGI1-affected individuals report auditory aura and one visual aura; three families with autosomal dominant epilepsy and auditory features have novel LGI1 mutations.

  12. Downregulation of LGI1 promotes tumor metastasis in esophageal squamous cell carcinoma.

  13. This study expands the phenotypic spectrum associated with Autosomal dominant lateral temporal lobe epilepsy due to LGI1 mutation and underlines the need for more systematic evaluation of Attention-deficit hyperactivity disorder and related symptoms.

  14. The LGI1-ADAM22 interaction is neutralized by autoantibodies to epilepsy-related LGI1 in limbic encephalitis.

  15. This study demonistrated that Low penetrance of autosomal dominant lateral temporal epilepsy in Italian families without LGI1 mutations.

  16. Cerebrocortical manifestations are recorded in 76% of patients with LGI1 immunoglobulin G (IgG) seropositivity.

  17. Antibodies bind to proteins complexed with voltage-gated potassium channel (VGKC) complex in two patients with LG11-antibody encephalitis.

  18. This is the first microdeletion affecting LGI1 identified in autosomal dominant lateral temporal epilepsy.

  19. The N-terminal leucine-rich repeat region of the LGI1 gene is likely to play a major role in pathogenesis of autosomal dominant partial epilepsy with auditory features.

  20. LGI1, a secreted synaptic protein mutated to cause human partial epilepsy, regulates a seizure-induced circuit response by redistributing Kv4.2 channels to the neuronal surface in a transgenic mouse model.

Mouse (Murine) Leucine-Rich, Glioma Inactivated 1 (LGI1) Interaktionspartner

  1. LGI1 is expressed at the axonal initial segment and regulates action potential firing by setting the density of the axonal Kv1.1 channels.

  2. LGI1 has a role in regulating cortical development, which is increasingly becoming recognized as one of the causes of idiopathic epilepsy.

  3. LGI1 and ADAM22 form an essential synaptic organizing complex that coordinates the maturation of excitatory synapses by regulating the functional incorporation of PSD-95

  4. Review article demonstrating that LGI1 may be an essential player in the development of the brain

  5. Glutamatergic neuron-targeted loss of Lgi1 causes a severe epileptic phenotype; Lgi1 displays an essential role in brain during the whole life.

  6. Lgi1 contains nuclear localization signal that mediates Lgi1 localization to cytoplasm and nucleus in CNS embryonic neurons.

  7. This study demonistrated that LGI1 plays a critical role in both dendritic and axonal pruning, we identify a novel molecular pathway in synapse and circuit remodeling.

  8. Lgi1 may have a role in establishing normal brain architecture and neuronal functions during brain development suggesting that it may be involved in neurogenesis and neuronal plasticity

  9. LGI1(+/-) and LGI1(-/-) mice may provide useful models for lateral temporal lobe epilepsy, and more generally idiopathic focal epilepsy.

  10. Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability.

  11. in the brain of C57BL/6J adult mice by in situ hybridization. We found that the LGI1 transcript is mainly expressed in the dentate gyrus and CA3 field of the hippocampus.

  12. Reduce levels of secreted LGI1 is associated with autosomal dominant partial epilepsy with auditory features

  13. Two protein isoforms encoded by LGI1/epitempin are differentially expressed in mouse brain: the 60-kDa form is detected in the microsomal fraction, while the 65-kDa product is found in the cytosolic fraction.

  14. This study was the first to determine a specific profile of Lgi1 gene expression during central nervous system development, which suggests a possible inhibitory function in latter stages of development.

  15. study identified LGI1 as a specific binding partner of ADAM22 protein from mouse brain, and demonstrated the specific interaction between LGI1 and ADAM22

  16. The normal postnatal maturation of presynaptric and postsynaptic functions was arrested by the 835delC mutant Lgi1.

Zebrafish Leucine-Rich, Glioma Inactivated 1 (LGI1) Interaktionspartner

  1. Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype.

Leucine-Rich, Glioma Inactivated 1 (LGI1) Antigen-Profil

Protein Überblick

This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.

Genbezeichner und Symbole assoziert mit LGI1

  • leucine rich glioma inactivated 1 (LGI1) Antikörper
  • leucine-rich repeat LGI family, member 1 (Lgi1) Antikörper
  • leucine-rich, glioma inactivated 1 (Lgi1) Antikörper
  • leucine-rich, glioma inactivated 1 (LGI1) Antikörper
  • leucine-rich, glioma inactivated 1 (lgi1) Antikörper
  • leucine rich glioma inactivated 1 (Lgi1) Antikörper
  • leucine-rich, glioma inactivated 1a (lgi1a) Antikörper
  • ADLTE Antikörper
  • ADPAEF Antikörper
  • ADPEAF Antikörper
  • BB130740 Antikörper
  • EPITEMPIN Antikörper
  • EPT Antikörper
  • ETL1 Antikörper
  • fb78h12 Antikörper
  • IB1099 Antikörper
  • LGIa Antikörper
  • MGC146600 Antikörper
  • wu:fb78h12 Antikörper
  • zgc:65886 Antikörper

Bezeichner auf Proteinebene für LGI1

epitempin-1 , leucine-rich glioma-inactivated protein 1 , leucine-rich, glioma inactivated 1 , leucine-rich repeat LGI family, member 1 , putative leucine-rich glioma inactivated 1 , polymorphic marker clone YB07 , leucine-rich glioma-inactivated protein 1-like , leucine-rich, glioma inactivated 1a

GENE ID SPEZIES
9211 Homo sapiens
56839 Mus musculus
252892 Rattus norvegicus
423802 Gallus gallus
450619 Pan troglodytes
477777 Canis lupus familiaris
617080 Bos taurus
700520 Macaca mulatta
779819 Xenopus (Silurana) tropicalis
100172937 Pongo abelii
100219007 Taeniopygia guttata
100415038 Callithrix jacchus
100597927 Nomascus leucogenys
100726518 Cavia porcellus
323011 Danio rerio
100344253 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-Leucine-Rich, Glioma Inactivated 1 (LGI1) Antikörper
Haben Sie etwas anderes gesucht?