anti-Interleukin 18 Binding Protein (IL18BP) Antikörper

The protein encoded by IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. Zusätzlich bieten wir Ihnen IL18BP Kits (43) und IL18BP Proteine (29) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
IL18BP 16068 Q9Z0M9
IL18BP 10068 O95998
IL18BP 84388  
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Top anti-IL18BP Antikörper auf antikoerper-online.de

Showing 10 out of 155 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis of extracts from rat spleen, using IL18BP Antibody. ABIN6275773 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL 11 bis 12 Tage
$390.77
Details
Human Maus Unkonjugiert ELISA, WB   100 μL Verfügbar
$363.46
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat lung tissue labeled with Anti-IL18BP Polyclonal Antibody, Unconjugated (ABIN752938) at 1:200 followed by conjugation to the secondary antibody 100 μL 3 bis 7 Tage
$329.45
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg 13 bis 16 Tage
$350.00
Details
Maus Kaninchen Unkonjugiert ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin- embedded brain tissue 100 μg 15 bis 18 Tage
$360.00
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin- embedded liver tissue 100 μg 13 bis 16 Tage
$380.00
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert ICC, IHC (fro), IHC (p), ELISA, WB 100 μg 13 bis 16 Tage
$259.00
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg 11 bis 14 Tage
$419.83
Details
Maus Kaninchen Unkonjugiert ELISA, WB Western blot analysis of IL18 binding protein using anti-IL18 binding protein antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: mouse heart tissue lysate, Lane 2: mouse brain tissue lysate, Lane 3: rat heart tissue lysate.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-IL18 binding protein antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for IL18 binding protein at approximately 43KD. The expected band size for IL18 binding protein is at 21KD. 100 μg 4 bis 6 Tage
$240.00
Details

Am meisten referenzierte anti-IL18BP Antikörper

  1. Human Polyclonal IL18BP Primary Antibody für ICC, FACS - ABIN152337 : Novick, Kim, Fantuzzi, Reznikov, Dinarello, Rubinstein: Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. in Immunity 1999 (PubMed)
    Show all 4 Pubmed References

  2. Polyclonal IL18BP Primary Antibody für WB - ABIN540854 : He, Lu, Altmann, Hoke, Ljubanovic, Jani, Dinarello, Faubel, Edelstein: Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury. in American journal of physiology. Renal physiology 2008 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal IL18BP Primary Antibody für IF (p), IHC (p) - ABIN752938 : Businaro, Corsi, Azzara, Di Raimo, Laviola, Romano, Ricci, Maccarrone, Aronica, Fuso, Ricci: Interleukin-18 modulation in autism spectrum disorders. in Journal of neuroinflammation 2016 (PubMed)

Weitere Antikörper gegen IL18BP Interaktionspartner

Rhesus Monkey Interleukin 18 Binding Protein (IL18BP) Interaktionspartner

  1. A full-length cDNA of the rhesus IL-18BP (RhIL-18BP) from the spleen of rhesus macaques, was cloned and sequenced.

Rabbit Interleukin 18 Binding Protein (IL18BP) Interaktionspartner

  1. Pressure overload, while enhancing IL-18 and IL-18R expression in hypertrophied and failing hearts, markedly attenuated the level of expression of the endogenous IL-18 antagonist IL-18BP.

Mouse (Murine) Interleukin 18 Binding Protein (IL18BP) Interaktionspartner

  1. IL-18BP possessed protective effect against LPS-induced ALI, which might be associated with its regulation of NF-kappaB and Nrf2 activities.

  2. asthma is very likely to be determined by balance of IL-18/IL-18BP/IL-18R expression in inflammatory cells.

  3. IL-18BP ameliorates cardiac ischemia/reperfusion injury in part through suppression of Th17 differentiation.

  4. Data show that IL-18bp acts as a sensor for IFN-gamma and can regulate both Th1 and Th17 responses in the CNS.

  5. Administratioan of murine IL-18BP at the time of the booster injection of bovine CII reduces the progressive severity of collagen-induced arthritis; both clinical disease activity and histological scores are decreased by 50%.

  6. functional polarization of Ag-specific CD4(+) Th2 cells entering the CNS during the accelerating phase of experimental autoimmune encephalomyelitis is flexible and dependent on IL-18, which is overturned by IL-18 binding protein

  7. IL-18 and IL-18BP may have roles in testicular development, and also in the regulation of testicular functions under physiological conditions

  8. A single intravenous dose of recombinant mouse IL18BP decreased neointimal hyperplasia and improved arterial L/A ratios in an atherosclerotic balloon-injury animal model.

Human Interleukin 18 Binding Protein (IL18BP) Interaktionspartner

  1. asthma is very likely to be determined by balance of IL-18/IL-18BP/IL-18R expression in inflammatory cells.

  2. these results were corroborated in female osteoporotic subjects where decreased serum IL-18BP levels and enhanced serum IL-18 levels were observed. Our study forms a strong basis for using humanized IL-18BP towards the treatment of postmenopausal osteoporosis.

  3. epigenetic silencing by single CpG methylation determines differential IL18BP inducibility in monocytic versus epithelial cells. T

  4. a large proportion blood basophils from patients with asthma express IL-18 and IL-18BP. mast cells and basophils are implicated in the pathogenesis of asthma via an IL-18-related mechanism.

  5. The maintenance of normal production of IL-18BP may contribute, at least in part, to the ability ofLong Term Non-Progressors to delay AIDS progression.

  6. Platelets also contain the IL-18 antagonist, the IL-18-Binding Protein (IL-18BP); however, it is not synthesized in them de novo, is present in pre-made form and is released irrespective of platelet activation.

  7. The serum levels of IL-37, which were correlated with antibody production and the serum levels of total IL-18 and IL-18BP, were elevated in the patients with primary Sjogren's syndrome.

  8. an imbalance in the production of IL-18 and its antagonist (an increase in the production of IL-18 with a decrease, no increase or an insufficient increase in the production of IL-18BP) has been described in many chronic inflammatory diseases in humans.

  9. IL-18, IL-18R and IL-18BP expression in eosinophil are involved in the inflammatory reaction of asthma.

  10. the inhibition of IL-18 signaling by IL-18BPa may be involved in the development of pulmonary vascular involvement leading to pulmonary hypertension and modulate the systemic inflammation in systemic sclerosis

  11. The natural IL-18 inhibitor IL-18BP further regulates IL-18 activity in the extracellular environment. Review.

  12. imbalance of IL-18/IL-18BP ratio in IgA nephropathy especially in patients with arteriolar lesions

  13. IL-18, IL-18BP, and IL-18R may have roles in the pathogenesis of epithelial ovarian carcinoma

  14. HPV16 E7 oncoprotein increases production of the IL18BP in keratinocytes.

  15. these data indicate that IL-18BP, which is produced in EOC in response to microenvironmental factors, may inhibit endogenous or exogenous IL-18 activity

  16. Data suggest that the imbalance of IL-18/IL-18BP might play an important role in the pathogenesis of systemic juvenile idiopathic arthritis (SJIA) and it might go hand-in-hand with the severity of SJIA.

  17. Due to highly significant increases in circulating IL-18BP in schizophrenia compared to controls, the levels of free IL-18 are not significantly different between schizophrenic groups.

  18. Imbalance between IL-18 and IL-18BP may play an important role in pathogenesis of idiopathic thrombocytopenic purpura.

  19. High IL-18 BP levels indicate the severity of existing glomerular injury in systemic lupus erythematosus.

  20. The balance between interleukin-18 (IL-18) and its endogenous antagonist, IL-18 binding protein (IL-18BP), was evaluated in children with Henoch-Schonlein purpura.

IL18BP Antigen-Profil

Protein Überblick

The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Genbezeichner und Symbole assoziert mit IL18BP

  • interleukin 18 binding protein (IL18BP) Antikörper
  • interleukin 18 binding protein (Il18bp) Antikörper
  • Igifbp Antikörper
  • IL-18BP Antikörper
  • IL18BP Antikörper
  • IL18BPa Antikörper
  • MC54L Antikörper

Bezeichner auf Proteinebene für IL18BP

interleukin 18 binding protein , interferon gamma inducing factor binding protein , interferon gamma-inducing factor-binding protein , interleukin-18-binding protein , IL-18BP , MC51L-53L-54L homolog gene product , tadekinig-alfa , interleukin-18 binding protein

GENE ID SPEZIES
476818 Canis lupus familiaris
748234 Pan troglodytes
100144607 Macaca mulatta
100340371 Oryctolagus cuniculus
16068 Mus musculus
10068 Homo sapiens
84388 Rattus norvegicus
617470 Bos taurus
Ausgewählte Anbieter für anti-IL18BP (IL18BP) Antikörper
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