anti-Histone Cluster 1, H1c (HIST1H1C) Antikörper

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human HIST1H1C HIST1H1C 3006 P16403
Anti-Maus HIST1H1C HIST1H1C 50708 P15864
Anti-Ratte HIST1H1C HIST1H1C 684681  
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Top anti-HIST1H1C Antikörper auf antikoerper-online.de

Showing 10 out of 70 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert ChIP, WB WB Suggested Anti-HIST1H1C Antibody Titration:  0.2-1 ug/ml  Positive Control:  721_B cell lysate HIST1H1C is supported by BioGPS gene expression data to be expressed in 721_B Chromatin Immunoprecipitation (ChIP) Using HIST1H1C antibody - middle region  and HCT116 Cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of HIST1H1C Antibody (Center) (ABIN653110) in Hela cell line lysates (35 µg/lane). HIST1H1C (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of HIST1H1C Antibody in Hela cell line lysates (35ug/lane) 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
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Human Kaninchen Unkonjugiert IF, IHC, IP, WB 100 μL Anmelden zum Anzeigen 16 Days
$476.15
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Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
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Human Kaninchen Unkonjugiert WB HIST1H1C antibody used at 0.25 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Western Blot of Histone H1.2 antibody using AP54998SU-N at 1/2000 dilution. 0.2 mL Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: Histone H1.2 Antibody [NBP2-16845] - Sample (30 ug of whole cell lysate) A: HeLa B: HeLa nucleus 12% SDS PAGE gel, diluted at 1:10000. Immunocytochemistry/Immunofluorescence: Histone H1.2 Antibody [NBP2-16845] - Confocal immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Histone H1. 2 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with Alpha-tubulin antibody (Red) at 1:2000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB 100 μL Anmelden zum Anzeigen 6 bis 7 Tage
$351.13
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Weitere Antikörper gegen HIST1H1C Interaktionspartner

Human Histone Cluster 1, H1c (HIST1H1C) Interaktionspartner

  1. results define a network of E2F (zeige E2F1 Antikörper) target genes as susceptible to the regulatory influence of H1.2, where H1.2 augments global association of pRb (zeige RB1 Antikörper) with chromatin, enhances transcriptional repression by pRb (zeige RB1 Antikörper), and facilitates pRb (zeige RB1 Antikörper)-dependent cell-cycle arrest

  2. BRG1 (zeige SMARCA4 Antikörper) participates in gene repression by interacting with H1.2, facilitating its deposition and stabilizing nucleosome positioning around the transcription start site.

  3. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. Also, the study reports the observation of the H1.2 SNP variant A18V in MCF-10A cells.

  4. Histone H1.2-T165 post translational modifications are dispensable for chromatin binding and cell proliferation while the H1.4-K26 (zeige KRT26 Antikörper) modifications are essential for proper cell cycle progression.

  5. H1.2 interacts with Cul4A (zeige CUL4A Antikörper) and PAF1 (zeige PEX2 Antikörper) to activate developmental regulatory genes.

  6. H1.2 is less abundant than other histone H1 (zeige H1F0 Antikörper) variants at the transcription start sites of inactive genes, and promoters enriched in H1.2 are different from those enriched in other histone H1 (zeige H1F0 Antikörper) variants and tend to be repressed.

  7. Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.

  8. These data suggest that p53 (zeige TP53 Antikörper) acetylation-H1.2 phosphorylation cascade serves as a unique mechanism for triggering p53 (zeige TP53 Antikörper)-dependent DNA damage response pathways.

  9. confirmed N-terminal acetylation on all isoforms plus a single internal acetylation site; phosphorylation sites were located on peptides containing the cyclin dependent kinase (zeige CDK1 Antikörper) (CDK (zeige CDK4 Antikörper)) consensus motif

  10. The binding of histone H1 (zeige H1F0 Antikörper) to a general amyloid-like motif indicates that histone H1 (zeige H1F0 Antikörper) may play an important common role in diseases associated with amyloid-like fibrils.

Mouse (Murine) Histone Cluster 1, H1c (HIST1H1C) Interaktionspartner

  1. Histone H1c gene expression is developmentally up-regulated to promote facultative heterochromatin in mature rod photoreceptors.

  2. These results integrate the localization of an understudied type of chromatin proteins, namely the H1 variants, into the epigenome map of mouse ESCs (zeige NR2E3 Antikörper).

  3. The N-terminal domain contributes toward the differential chromatin binding affinity, whereas the C-terminal domain contributes toward distinct nucleosomal interface of isotypes H10 (zeige H1F0 Antikörper) and H1c.

  4. The amount of the linker histone H1c is strongly reduced in nuclear extracts of SCA7 (zeige ATXN7 Antikörper) retinas and that the cellular distribution of H1c is particularly altered in the facultative heterochromatin compartment.

  5. The modular pattern of DNA methylation (zeige HELLS Antikörper) in the Ig heavy chain locus and histone modifications appears to be determined by at least 2 factors: the B-cell-specific transcription factor Pax5 (zeige PAX5 Antikörper) and linker histone H1 (zeige H1F0 Antikörper).

  6. These observations reveal a mode of p53 (zeige TP53 Antikörper) regulation mediated by CHD8 (zeige CHD8 Antikörper), which may set a threshold for induction of apoptosis during early embryogenesis by counteracting p53 (zeige TP53 Antikörper) function through recruitment of histone H1 (zeige H1F0 Antikörper).

  7. H1 isoforms H1.0, H1.1, and H1.2 are non-responsive to hormone whereas prolonged dexamethasone treatment effectively dephosphorylated the H1.3, H1.4, and H1.5 isoforms

HIST1H1C Antigen-Profil

Protein Überblick

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Genbezeichner und Symbole assoziert mit HIST1H1C

  • histone cluster 1 H1 family member c (HIST1H1C) Antikörper
  • histone cluster 1, H1c (Hist1h1c) Antikörper
  • histone cluster 1, H1c (HIST1H1C) Antikörper
  • histone cluster 1 H1 family member c (Hist1h1c) Antikörper
  • 0610008C09Rik Antikörper
  • H1.2 Antikörper
  • H1c Antikörper
  • H1f2 Antikörper
  • H1s-1 Antikörper
  • H1var1 Antikörper
  • His1a Antikörper

Bezeichner auf Proteinebene für HIST1H1C

H1 histone family, member 2 , histone 1, H1c , histone H1.2 , histone H1c , histone H1d , histone H1s-1 , H1 VAR.1 , histone H1 , CTL-1 , histone H1.1 , histone cluster 1, H1c

GENE ID SPEZIES
3006 Homo sapiens
50708 Mus musculus
513971 Bos taurus
684681 Rattus norvegicus
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