Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Proteine (GADD45GIP1)

GADD45GIP1 encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. Zusätzlich bieten wir Ihnen Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Antikörper (33) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GADD45GIP1 90480 Q8TAE8
GADD45GIP1 102060 Q9CR59
Ratte GADD45GIP1 GADD45GIP1 288916 Q5XJW2
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Top Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Proteine auf antikoerper-online.de

Showing 7 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 15 bis 19 Tage
$492.31
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,553.83
Details
Hefe REACT_Green monkey His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,553.83
Details

GADD45GIP1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) Interaktionspartnern

Human Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) Interaktionspartner

  1. NRF2 Ser40 phosphorylation was inhibited in Crif1-deficient bone marrow multipotent mesenchymal stromal cells even in the presence of three kinds of PKC agonists, suggesting that CRIF1 might co-activate PKC-delta to phosphorylate NRF2 Ser40.

  2. strongly suggest that CRIF1 deficiency promotes endothelial cell inflammation by increasing VCAM-1 expression, elevating inflammatory cytokines levels, and activating the transcription factor NF-kappaB, all of which were inhibited by SIRT1 overexpression

  3. Results demonstrate that knockdown of CRIF1 in HUVECs induces mitochondrial dysfunction and reduces SIRT1 expression along with decreased eNOS phosphorylation and increased eNOS acetylation, thereby promoting endothelial dysfunction. These findings indicate that CRIF1 plays an important role in maintaining mitochondrial and endothelial function through its effects on the SIRT1-eNOS pathway.

  4. SNF5 is indispensable for CRIF1-enhanced p53 activity and its function in the suppression of cell cycle arrest in human cancer cells.

  5. Study shows that Lck interacts with CRIF1 in the mitochondria and negatively regulates CRIF1-mediated translation of mitochondrion-encoded proteins.

  6. our results support a novel function of nuclear Lck in promoting human leukemic T cell survival through interaction with a tumor suppressor, CRIF1

  7. Crif1 is an indispensable regulator of PKAalpha cat that modulates the PKA/CREB signaling pathway to promote adipogenic differentiation of bone marrow mesenchymal stem cells after irradiation

  8. The results identify the ROS-Sp1-Crif1 pathway to be a new mechanism underlying Abeta-induced mitochondrial dysfunction and suggest that ROS-mediated downregulation of Crif1 is a crucial event in AD pathology.

  9. CRIF1 knockdown partially induces endothelial activation via increased ROS production and phosphorylation of p66shc

  10. CRIF1 may play a regulatory role in the BM microenvironment-induced leukemia cell cycle arrest possibly through interacting with CDK2 and acting as a cyclin-dependent kinase inhibitor.

  11. CKbetaBP2/CRIF1 is expressed with STAT3 in prostate cancer where STAT3 may help to offset the AR repressor effect of CKbetaBP2/CRIF1.

  12. results indicated cell cycle arrest of Jurkat cells in the G0/G1 phase to be induced by primary cultured leukemic BMSCs associated with increased expression of CRIF1 by leukemic cells

  13. CRIF1, unlike KEAP1 (which only interacts with N-terminal region of NRF2), physically interacts with both N- and C-terminal regions of NRF2 and promotes NRF2 ubiquitination and subsequent proteasome-mediated NRF2 protein degradation

  14. results suggest that CRIF1 is a novel nuclear protein that interacts with Gadd45 and may play a role in negative regulation of cell cycle progression and cell growth

  15. Phosphorylation of serine-221 in CKBBP2/CRIF1 promotes proliferation of green monkey COS7 cells.

  16. NAC-1 contributes to tumor growth and survival by at least inhibiting Gadd45GIP1 expression, which has a tumor suppressor effect in cancer cells.

  17. Results suggest that CRIF1 acts as an AR corepressor and may play an important role in the regulation of AR-positive growth of prostate cancer.

Mouse (Murine) Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) Interaktionspartner

  1. Crif1(beta-/-) mouse is a useful model for the study of beta cell failure caused by mitochondrial OxPhos dysfunction.

  2. The results identify the ROS-Sp1-Crif1 pathway to be a new mechanism underlying Abeta-induced mitochondrial dysfunction and suggest that ROS-mediated downregulation of Crif1 is a crucial event in AD pathology.

  3. CRIF1 knockdown partially induces endothelial activation via increased ROS production and phosphorylation of p66shc

  4. Study showed that loss of Crif1 impairs mitochondrial oxidative phosphorylation and adipocyte differentiation in vitro and in vivo.

  5. Crif1 plays a critical role in the maintenance of both mitochondrial structure and respiration in cardiac muscles.

  6. Although adipose-specific Crif1-haploinsufficient mice showed normal growth and development, they became insulin-resistant.

  7. CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane.

  8. Results reveal that Crif1 is a novel and essential transcriptional coactivator of Elf3 for the terminal differentiation of absorptive enterocytes.

  9. Crif1 is a novel and essential transcriptional coactivator of STAT3 that modulates its DNA binding ability.

Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) Protein Überblick

Protein Überblick

This gene encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. The encoded protein may interact with other cell cycle regulators.

Genbezeichner und Symbole assoziert mit GADD45GIP1

  • growth arrest and DNA-damage-inducible, gamma interacting protein 1 (gadd45gip1)
  • GADD45G interacting protein 1 (GADD45GIP1)
  • growth arrest and DNA-damage-inducible, gamma interacting protein 1 (Gadd45gip1)
  • GADD45G interacting protein 1 (Gadd45gip1)
  • 2310040G17Rik Protein
  • AI425883 Protein
  • CKBBP2 Protein
  • Crif1 Protein
  • PLINP Protein
  • PLINP-1 Protein
  • Plinp1 Protein
  • PRG6 Protein
  • si:dkey-194e13.6 Protein

Bezeichner auf Proteinebene für GADD45GIP1

CKII beta binding protein 2 , CKII beta-associating protein , CR6 interacting factor 1 , growth arrest and DNA damage-inducible proteins-interacting protein 1 , growth arrest- and DNA damage-inducible GADD45G-interacting protein , p53-responsive gene 6 protein , papillomavirus L2 interacting nuclear protein 1 , growth arrest and DNA-damage-inducible proteins-interacting protein 1

GENE ID SPEZIES
402803 Danio rerio
90480 Homo sapiens
102060 Mus musculus
288916 Rattus norvegicus
504718 Bos taurus
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