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GADD45GIP1 Protein (Myc-DYKDDDDK Tag)

GADD45GIP1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2721585
  • Target Alle GADD45GIP1 Proteine anzeigen
    GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
    Protein-Typ
    Recombinant
    Spezies
    • 3
    • 1
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses GADD45GIP1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human GADD45GIP1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GADD45GIP1 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
    Andere Bezeichnung
    Gadd45gip1 (GADD45GIP1 Produkte)
    Synonyme
    si:dkey-194e13.6 Protein, CKBBP2 Protein, CRIF1 Protein, PLINP Protein, PLINP-1 Protein, PRG6 Protein, Plinp1 Protein, 2310040G17Rik Protein, AI425883 Protein, Crif1 Protein, growth arrest and DNA-damage-inducible, gamma interacting protein 1 Protein, GADD45G interacting protein 1 Protein, gadd45gip1 Protein, GADD45GIP1 Protein, Gadd45gip1 Protein
    Hintergrund
    Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. [UniProtKB/Swiss-Prot Function]
    Molekulargewicht
    25.2 kDa
    NCBI Accession
    NP_443082
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