Glycoprotein A33 (Transmembrane) Proteine (GPA33)

Human Glycoprotein A33 (Transmembrane) (GPA33) Interaktionspartner

1. A33 shows similar sensitivity to but is more specific than CDX2 (zeige CDX2 Proteine) as an immunomarker of colorectal carcinoma

2. A33 expression is directly correlated to colorectal tumor differentiation.

3. Data indicate that EpCAM (zeige EPCAM Proteine)- and A33-Exos were released from the apical and basolateral surfaces, respectively.

4. Data indicate positive staining was observed for both A33 expression and KRN330 binding from patients biopsied on Day 8, 9 or 14 following initial dosing of 3 mg/kg.

5. The A33-dependent incorporation of B5 into extracellular enveloped vaccinia virions is mediated through an interaction between their lumenal domains.

6. Increased interaction between vaccinia virus proteins A33 and B5 is detrimental to infectious extracellular enveloped virion production.

7. cloning, chromosomal localizations, exon-intron structures and transcription start sites - target gene for the intestine-specific homeobox (zeige ISX Proteine) transcription factor, CDX1 (zeige CDX1 Proteine).

8. Regulation of A33 antigen expression by GKLF (zeige KLF4 Proteine).

Mouse (Murine) Glycoprotein A33 (Transmembrane) (GPA33) Interaktionspartner

1. Gpa33(-/-) mice provide a valuable model to study the mechanisms linking intestinal permeability and multiple inflammatory pathologies.

2. A33 antigen-deficient mice have defective colonic mucosal repair.

3. cloning, chromosomal localizations, exon-intron structures and transcription start sites - target gene for the intestine-specific homeobox (zeige ISX Proteine) transcription factor, CDX1 (zeige CDX1 Proteine)