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The protein encoded by GEM belongs to the RAD/GEM family of GTP-binding proteins. Zusätzlich bieten wir Ihnen GEM Antikörper (60) und GEM Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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Rad, Gem and Rem (zeige REM1 Proteine) all reduce depolarization-dependent Ca2 (zeige CA2 Proteine)+ entry in developing myotubes.
These results suggest that Gem plays an important role in normal beta-cell function by regulation of calcium signalling.
Mechanism of the inhibition of calcium channel activity by Gem.
docking of the RGK protein to the nucleotide-kinase domain of the Cavbeta subunit is reminiscent of the binding of GMP (zeige NT5C2 Proteine) to guanylate kinase (zeige GUK1 Proteine)
Results identify specific nuclear localization signals (NLS (zeige ALDH1A2 Proteine)) in Kir/Gem that are both required and sufficient for nuclear transport.
Down regulation of Gem expression was involved in the pathogenesis of hepatocellular carcinoma (HCC (zeige FAM126A Proteine)), and it might be a favorable independent prognostic parameter for HCC (zeige FAM126A Proteine).
These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages.
Gem is involved both in T-cell spontaneous cell migration as well as chemotaxis and plays an important role in cell-to-cell HTLV-1 viral transmission.
Data show a mechanism by which GTPase Gem contributes to the mitotic progression by maintaining correct spindle length through the kinesin Kif9.
Gem contains two candidate inhibitory sites, each capable of producing full inhibition of P/Q-type Ca(2 (zeige CA2 Proteine)+) channels.
GEM plays a key role during C. pneumoniae entry into human cells.
We discuss the structural and functional properties of RGK proteins and highlight recent work addressing the mechanism of Gem regulation by calmodulin (zeige CALM1 Proteine) and 14-3-3 (zeige YWHAQ Proteine).
crystallographic structure and biochemical characterization indicate that Gem G-domain markedly prefers GDP over GTP (zeige AK3 Proteine)
Gem is a bona fide GTPase (zeige RACGAP1 Proteine) that exhibits striking structural and biochemical features that should impact its regulation and cellular activities
The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
GTP-binding mitogen-induced T-cell protein
, GTP-binding protein GEM
, GTP-binding protein overexpressed in skeletal muscle
, RAS-like protein KIR
, kinase-inducible Ras-like protein
, GTP binding protein overexpressed in skeletal muscle
, Gem GTPase
, GTP binding protein gene overexpressed in skeletal muscle
, GTP binding protein (gene overexpressed in skeletal muscle)