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GEM Produkte

(GTP Binding Protein Overexpressed in Skeletal Muscle (GEM))
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011].

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Ausgewählte GEM Kategorien

GEM Antikörper

High quality antibodies with extensive validation data.

GEM ELISA Kits

Reliable ELISA kits for a wide range of species.

GEM Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GEM Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation IHC, WB
Validierungen
  • (4)
Kat. Nr. ABIN2775304
Menge 100 μL
Datenblatt Datenblatt

Applikation IHC, IHC (p), WB
Validierungen
  • (3)
Kat. Nr. ABIN203412
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Human, Mouse, Rat
Applikation IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN630220
Menge 100 μg
Datenblatt Datenblatt

Empfohlene GEM ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1135704
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1135705
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GEM Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3120438
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3080640
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354994
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GEM Produkten

Scamps, Sangari, Bowerman, Rousset, Bellis, Cens, Charnet: "Nerve injury induces a Gem-GTPase-dependent downregulation of P/Q-type Ca2+ channels contributing to neurite plasticity in dorsal root ganglion neurons." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 2, pp. 351-66, (2015) (PubMed).

Laurberg, Jensen, Schepeler, Borre, Ørntoft, Dyrskjøt: "High expression of GEM and EDNRA is associated with metastasis and poor outcome in patients with advanced bladder cancer." in: BMC cancer, Vol. 14, pp. 638, (2014) (PubMed).

Wang, Johnston, Chou, Dean: "A systemic network for Chlamydia pneumoniae entry into human cells." in: Journal of bacteriology, Vol. 192, Issue 11, pp. 2809-15, (2010) (PubMed).

Frampton, Stolz, Uchida, Goins, Cohen, Glorioso: "Equine herpesvirus 1 enters cells by two different pathways, and infection requires the activation of the cellular kinase ROCK1." in: Journal of virology, Vol. 81, Issue 20, pp. 10879-89, (2007) (PubMed).

Synonyme und alternative Namen zu GEM

GTP binding protein overexpressed in skeletal muscle (GEM), GTP binding protein overexpressed in skeletal muscle (gem), GTP binding protein overexpressed in skeletal muscle (Gem), geminin, DNA replication inhibitor (GMNN), GTP binding protein (gene overexpressed in skeletal muscle) (Gem), AV020497, DKFZp470D0612, GEM, Gem, KIR, kir, LOC100221129, xgem, zgc:153003

Bezeichner auf Proteinebene für GEM

  • GTP-binding mitogen-induced T-cell protein
  • GTP-binding protein GEM
  • GTP-binding protein overexpressed in skeletal muscle
  • RAS-like protein KIR
  • kinase-inducible Ras-like protein
  • GTP binding protein overexpressed in skeletal muscle
  • Gem GTPase
  • GTP binding protein gene overexpressed in skeletal muscle
  • GTP binding protein (gene overexpressed in skeletal muscle)
  • geminin
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