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GEMIN5 Produkte

(Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Kategorien

This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].

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Ausgewählte GEMIN5 Kategorien

GEMIN5 Antikörper

High quality antibodies with extensive validation data.

GEMIN5 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GEMIN5 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IHC, WB
Validierungen
  • (4)
Kat. Nr. ABIN7267367
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC, IP, WB
Validierungen
Kat. Nr. ABIN7114527
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation ELISA
Validierungen
Kat. Nr. ABIN7095636
Menge 100 μL
Datenblatt Datenblatt

Empfohlene GEMIN5 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6229868
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GEMIN5 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN2721790
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3092746
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3136298
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GEMIN5 Produkten

Lampe, Kunze, Scholz, Brauß, Winslow, Simm, Keller, Heidler, Wittig, Brüne, Schmid: "Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors." in: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1861, Issue 2, pp. 147-157, (2018) (PubMed).

Francisco-Velilla, Fernandez-Chamorro, Dotu, Martinez-Salas: "The landscape of the non-canonical RNA-binding site of Gemin5 unveils a feedback loop counteracting the negative effect on translation." in: Nucleic acids research, Vol. 46, Issue 14, pp. 7339-7353, (2018) (PubMed).

Francisco-Velilla, Fernandez-Chamorro, Ramajo, Martinez-Salas: "The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation." in: Nucleic acids research, Vol. 44, Issue 17, pp. 8335-51, (2016) (PubMed).

Fernandez-Chamorro, Piñeiro, Gordon, Ramajo, Francisco-Velilla, Macias, Martinez-Salas: "Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5742-54, (2014) (PubMed).

Piñeiro, Fernández, Ramajo, Martínez-Salas: "Gemin5 promotes IRES interaction and translation control through its C-terminal region." in: Nucleic acids research, Vol. 41, Issue 2, pp. 1017-28, (2013) (PubMed).

Piñeiro, Ramajo, Bradrick, Martínez-Salas: "Gemin5 proteolysis reveals a novel motif to identify L protease targets." in: Nucleic acids research, Vol. 40, Issue 11, pp. 4942-53, (2012) (PubMed).

Pérez-Vilaró, Scheller, Saludes, Díez: "Hepatitis C virus infection alters P-body composition but is independent of P-body granules." in: Journal of virology, Vol. 86, Issue 16, pp. 8740-9, (2012) (PubMed).

Synonyme und alternative Namen zu GEMIN5

gem nuclear organelle associated protein 5 (GEMIN5), gem nuclear organelle associated protein 5 (Gemin5), gem (nuclear organelle) associated protein 5 (Gemin5), AA407055, AA407208, AI451603, BB194447, C330013N08, GEMIN-5

Bezeichner auf Proteinebene für GEMIN5

  • gem-associated protein 5
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