Formin Binding Protein 1-Like Proteine (FNBP1L)

The protein encoded by FNBP1L binds to both CDC42 and N-WASP. Zusätzlich bieten wir Ihnen FNBP1L Antikörper (60) und FNBP1L Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
FNBP1L 54874 Q5T0N5
FNBP1L 214459 Q8K012
FNBP1L 310839 Q2HWF0
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Top FNBP1L Proteine auf antikoerper-online.de

Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,743.67
Details

FNBP1L Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Formin Binding Protein 1-Like (FNBP1L) Interaktionspartnern

Human Formin Binding Protein 1-Like (FNBP1L) Interaktionspartner

  1. This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

  2. Loss of p53 tumor suppressor (zeige TP53 Proteine) function in breast cancers leads to upregulation of Toca-1, and results in enhanced risk of developing metastatic disease.

  3. GWAS results show that the aggregate effects of common SNPs explain 22-46% of phenotypic variation in childhood intelligence in the three largest cohorts; FNBP1L was also significantly associated with childhood intelligence

  4. findings suggest that Toca-1 functions at an early step in the dissemination of metastatic breast tumor cells; taken together, results identify Toca-1 as a proinvasive protein in breast adenocarcinoma

  5. Toca-1 knockdown cells also display a significant defect in EGF (zeige EGF Proteine)-induced motility and invasiveness.

  6. Cdc42 may influence endocytic membrane trafficking by regulating the formation and activity of the Toca-1/N-WASP complex.

  7. Toca-1 promotes actin nucleation by activating the N-WASP-WIP/CR16 complex, the predominant form of N-WASP in cells.

  8. a vesicle trafficking regulator Toca-1 regulates different aspects of neuronal morphology from N-WASP

  9. We show that actin tail initiation by S. flexneri requires Toca-1 for the conversion of N-WASP from a closed inactive conformation to an open active one.

  10. the Toca-1-N-WASP complex can link filopodial formation to endocytosis

Mouse (Murine) Formin Binding Protein 1-Like (FNBP1L) Interaktionspartner

  1. Toca-1(knockdown) cells have defects in formation of myotubes probably due to reduced activity of actin cytoskeleton regulators such as N-WASP.

Xenopus laevis Formin Binding Protein 1-Like (FNBP1L) Interaktionspartner

  1. This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

FNBP1L Protein Überblick

Protein Überblick

The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit FNBP1L

  • formin binding protein 1 like (FNBP1L)
  • formin binding protein 1-like (Fnbp1l)
  • formin binding protein 1-like (fnbp1l)
  • formin binding protein 1 like (fnbp1l)
  • formin binding protein 1 like L homeolog (fnbp1l.L)
  • formin binding protein 1 like S homeolog (fnbp1l.S)
  • 2610318I01Rik Protein
  • AW548221 Protein
  • C1orf39 Protein
  • fnbp1l Protein
  • MGC132162 Protein
  • RGD1305386 Protein
  • toca-1 Protein
  • toca1 Protein
  • zgc:100923 Protein

Bezeichner auf Proteinebene für FNBP1L

formin-binding protein 1-like , toca-1 , transducer of Cdc42-dependent actin assembly 1 , transducer of Cdc42-dependent actin assembly protein 1 , Cdc42 effector , formin binding protein 1-like , transducer of Cdc42-dependent actin assembly-1 , Transducer of Cdc42-dependent actin assembly protein 1

GENE ID SPEZIES
54874 Homo sapiens
214459 Mus musculus
310839 Rattus norvegicus
424495 Gallus gallus
445240 Danio rerio
448740 Xenopus (Silurana) tropicalis
469385 Pan troglodytes
479942 Canis lupus familiaris
616665 Bos taurus
713578 Macaca mulatta
735241 Xenopus laevis
100032840 Monodelphis domestica
100059052 Equus caballus
100077332 Ornithorhynchus anatinus
100157977 Sus scrofa
100338578 Oryctolagus cuniculus
100405015 Callithrix jacchus
100448000 Pongo abelii
100476131 Ailuropoda melanoleuca
100559983 Anolis carolinensis
446802 Xenopus laevis
Ausgewählte Anbieter für FNBP1L Proteine (FNBP1L)
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