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DPPA5 encodes a protein that may function in the control of cell pluripotency and early embryogenesis.
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Our study provides new insight into the function of DPPA5 and NANOG regulation in human pluripotent stem cell .
Dppa5 is specifically and differentially expressed in human cells that have pluripotency and can be used as a marker of pluripotent stem cells.
Dppa5 reduces endoplasmic reticulum stress in hematopoietic stem cells.
developmental pluripotency associated 5 (Dppa5) was strongly expressed in mouse PGCs and the expression was rapidly downregulated during germ cell development.
Despite its specific expression in pluripotent cells and germ cells, ESG1 is dispensable for self-renewal of ES cells and establishment of germ cells.
ESG1 is an RNA-binding protein which associates with specific target transcripts such as Cdc25a (zeige CDC25A ELISA Kits), Cdc42 (zeige CDC42 ELISA Kits), Ezh2 (zeige EZH2 ELISA Kits), Nfyc (zeige NFYC ELISA Kits) and Nr5a2 (zeige NR5A2 ELISA Kits).
This gene encodes a protein that may function in the control of cell pluripotency and early embryogenesis. Expression of this gene is a specific marker for pluripotent stem cells. Pseudogenes of this gene are located on the short arm of chromosome 10 and the long arm of chromosomes 14 and 19.
developmental pluripotency-associated 5 protein
, embryonal stem cell specific gene 1
, ES cell-associated transcript 2 protein
, developmental pluripotency associated 5
, developmental pluripotency-associated protein 5A
, embryonal stem cell-specific gene 1 protein
, protein pH 34