Cyclin T2 Proteine (CCNT2)

The protein encoded by CCNT2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Zusätzlich bieten wir Ihnen Cyclin T2 Antikörper (38) und Cyclin T2 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CCNT2 905 O60583
CCNT2 72949  
Ratte CCNT2 CCNT2 304758  
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Baculovirus infected Insect Cells Human GST tag   50 μg Anmelden zum Anzeigen 10 bis 12 Tage
$624.55
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CCNT2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine)

Weitere Proteine zu Cyclin T2 (CCNT2) Interaktionspartnern

Human Cyclin T2 (CCNT2) Interaktionspartner

  1. miR (zeige MLXIP Proteine)-192 inhibits cell proliferation and induces G0/G1 cell cycle arrest in AML (zeige RUNX1 Proteine) by regulating the expression of CCNT2.

  2. the release of P-TEFb (zeige CCNT1 Proteine) from the 7SK snRNP (zeige LSM2 Proteine) led to increased synthesis of HEXIM1 (zeige HEXIM1 Proteine) but not HEXIM2 (zeige HEXIM2 Proteine)

  3. interaction with pRb (zeige RB1 Proteine)

  4. CycT2 not only contains two domains that target rna polymerase II but this substrate recognition is necessary for its transcriptional activity via DNA

  5. Data strengthen the hypothesis that Cyclin T2a plays a role in muscle differentiation, and propose PKNalpha (zeige PKN1 Proteine) as a novel partner of Cyclin T2a in this process.

  6. The results establish that cdk9 (zeige CDK9 Proteine)/cyclin T2a-mediated coactivation of MyoD (zeige MYOD1 Proteine) depends on serine 37 phosphorylation.

  7. These results suggest that acetylation of CDK9 (zeige CDK9 Proteine) is an important posttranslational modification that is involved in regulating P-TEFb (zeige CCNT1 Proteine) transcriptional elongation function.

  8. TAF7 interacts with the transcription factors, TFIIH and P-TEFb, resulting in the inhibition of their Pol II CTD kinase activities

  9. The tripartite protein-RNA complex formation between Hexim (zeige HEXIM1 Proteine), Cyclin T (zeige CCNT1 Proteine) and 7SK snRNA, was analyzed.

Mouse (Murine) Cyclin T2 (CCNT2) Interaktionspartner

  1. both isoforms of Cyclin T2 are able to activate the myogenic program but Cyclin T2b has a predominant role, in particular during the latest stages.

  2. miR (zeige MLXIP Proteine)-15a inhibited muscle differentiation at least in part by targeting Ccnt2; roles in spermatogenesis.

  3. activation of MyoD (zeige MYOD1 Proteine)-dependent transcription by cdk9 (zeige CDK9 Proteine)/cyclin T2

  4. despite numerous matings of heterozygous mice, we observed no CycT2(-/-) embryos, pups, or adult mice. This early lethality could have resulted from decreased expression of critical genes

Cyclin T2 (CCNT2) Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit Cyclin T2 Proteine (CCNT2)

  • cyclin T2 (CCNT2)
  • cyclin T2b (ccnt2b)
  • cyclin T2a (ccnt2a)
  • cyclin T2 S homeolog (ccnt2.S)
  • cyclin T2 (ccnt2)
  • cyclin T2 (Ccnt2)
  • 2900041I18Rik Protein
  • C81304 Protein
  • CCNT2 Protein
  • cycT Protein
  • CycT2 Protein
  • CycT2b Protein
  • fb16c03 Protein
  • MGC81210 Protein
  • wu:fb16c03 Protein
  • wu:fi17h07 Protein
  • wu:fj68b10 Protein
  • zgc:55357 Protein
  • zgc:55690 Protein

Bezeichner auf Proteinebene für Cyclin T2 Proteine (CCNT2)

cyclin T2 , cyclin-T2 , cyclin-T2-like , SDS-stable vimentin-bound DNA fragment HEF42VIM22 , cyclin T2a , cyclin T2b , subunit of positive elongation transcription factor b

GENE ID SPEZIES
100050510 Equus caballus
321464 Danio rerio
327568 Danio rerio
447439 Xenopus laevis
470546 Pan troglodytes
476126 Canis lupus familiaris
100349398 Oryctolagus cuniculus
100412841 Callithrix jacchus
100446291 Pongo abelii
100488125 Xenopus (Silurana) tropicalis
100011986 Monodelphis domestica
100552048 Anolis carolinensis
100599933 Nomascus leucogenys
905 Homo sapiens
424289 Gallus gallus
521089 Bos taurus
72949 Mus musculus
304758 Rattus norvegicus
101106913 Ovis aries
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