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Plays a role in angiogenesis and possibly in the development of tumors.
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Human Monoclonal CXCL17 Primary Antibody für CyTOF, FACS - ABIN4899780
Burkhardt, Maravillas-Montero, Carnevale, Vilches-Cisneros, Flores, Hevezi, Zlotnik: CXCL17 is a major chemotactic factor for lung macrophages. in Journal of immunology (Baltimore, Md. : 1950) 2014
High expression of CXCL17 correlates with shorter overall survival of breast cancer patients.CXCL17 interacts with CXCR8 in breast cancer cells.
CXCL17 attenuates Imiquimod -induced psoriasis-like skin inflammation by recruiting myeloid-derived suppressor cells and regulatory T cells , which may be important for regulating excessive inflammation in psoriasis skin.
This article shows that GPR35 (zeige GPR35 Antikörper) is the receptor of CXCL17.
CXCL17 production correlated with adverse immune infiltration and might be an important target for anti-HCC (zeige FAM126A Antikörper) therapies.
We conclude that CXCL17 is an antimicrobial mucosal chemokine (zeige CCL1 Antikörper) that may play a role in the pathogenesis of interstitial lung diseases
these results suggest that VCC-1 is involved in cisplatin-induced apoptosis of HepG2 cells, and also provides some evidence for VCC-1 as a potential cellular target for chemotherapy.
An Fc-fusion protein of 35kDa with a modified human immunoglobulin IgG1 Fc domain is capable of inhibiting CC chemokine-induced calcium flux, chemotaxis, and beta-arrestin recruitment in primary macrophages and transfected cells.
Immune surveillance occurs during the early intraepithelial stages of human pancreatic carcinogenesis and is mediated by expression of CXCL17 and ICAM2 (zeige ICAM2 Antikörper).
DMC (zeige DYM Antikörper) induces migration of monocytes and immature dendritic cells. Expression studies show that DMC (zeige DYM Antikörper) is constitutively expressed in lung, suggesting a potential role for DMC (zeige DYM Antikörper) in recruiting monocytes and dendritic cells from blood into lung parenchyma
VCC1 plays a role in angiogenesis and possibly in the development of tumors in some tissue types
CXCL17 is a novel macrophage chemoattractant that operates in mucosal tissues as a major regulator of inflammatory responses.
These results suggest that aberrant expression of CXCL17 in tumor cells recruits immature myeloid-derived cells and promotes tumor progression through angiogenesis.
VCC-1 plays a role in angiogenesis and possibly in the development of tumors in some tissue types[VCC-1]
Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections (By similarity).
C-X-C motif chemokine 17
, VEGF co-regulated chemokine 1
, dendritic cell and monocyte chemokine-like protein
, 13.6 kDa protein
, 13.6-kDa protein