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The protein encoded by CCR4 belongs to the G-protein-coupled receptor family . Zusätzlich bieten wir Ihnen CCR4 Kits (28) und CCR4 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 225 products:
Human Monoclonal CCR4 Primary Antibody für CyTOF, FACS - ABIN4899090
Aruga, Takeshita, Kotera, Okuyama, Matsushita, Ohta, Takeda, Yamamoto: Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2013
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Human Monoclonal CCR4 Primary Antibody für FACS - ABIN4895505
Aruga, Takeshita, Kotera, Okuyama, Matsushita, Ohta, Takeda, Yamamoto: Phase I clinical trial of multiple-peptide vaccination for patients with advanced biliary tract cancer. in Journal of translational medicine 2014
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Human Monoclonal CCR4 Primary Antibody für FACS - ABIN2689051
Bonecchi, Bianchi, Bordignon, DAmbrosio, Lang, Borsatti, Sozzani, Allavena, Gray, Mantovani, Sinigaglia: Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. in The Journal of experimental medicine 1998
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Human Monoclonal CCR4 Primary Antibody für FACS - ABIN2689052
Campbell, Haraldsen, Pan, Rottman, Qin, Ponath, Andrew, Warnke, Ruffing, Kassam, Wu, Butcher: The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. in Nature 1999
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Human Monoclonal CCR4 Primary Antibody für FACS - ABIN4895502
James, Gates, LaFond, Yamamoto, Ni, Mai, Gersuk, OBrien, Nguyen, Zeitner, Lanteri, Norris, Chaussabel, Malhotra, Kwok: Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome. in PLoS pathogens 2016
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Human Polyclonal CCR4 Primary Antibody für ICC, FACS - ABIN152140
Power, Meyer, Nemeth, Bacon, Hoogewerf, Proudfoot, Wells: Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line. in The Journal of biological chemistry 1995
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Human Polyclonal CCR4 Primary Antibody für WB - ABIN4289060
Park, Roh, Kim, Kim, Han, Hong: CCR5 plays an important role in resolving an inflammatory response to single-walled carbon nanotubes. in Journal of applied toxicology : JAT 2013
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Human Monoclonal CCR4 Primary Antibody für FACS - ABIN4895498
Antonelli, Mahnke, Hodge, Porter, Barber, DerSimonian, Greenwald, Roby, Mican, Sher, Roederer, Sereti: Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome. in Blood 2010
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Human Polyclonal CCR4 Primary Antibody für IF (p), IHC (p) - ABIN738666
Ge, Li, Jiang, You, Liu, Zhong, Huang, Xing: Integration of nondegradable polystyrene and degradable gelatin in a core-sheath nanofibrous patch for pelvic reconstruction. in International journal of nanomedicine 2015
Mouse (Murine) Polyclonal CCR4 Primary Antibody für ICC, FACS - ABIN152144
Herling, Patel, Weit, Lilienthal, Hallek, Keating, Jones: High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia. in Blood 2009
the expression of chemokine (zeige CCL1 Antikörper) receptors in different peripheral blood T-cell subsets in patients with polymyositis (PM) and dermatomyositis, was examined.
This review presents key clinical studies of Multiple sclerosis together with experimental studies in animals that have demonstrated functional roles of CCR4, CCL17 (zeige CCL17 Antikörper), and CCL22 (zeige CCL22 Antikörper) in experimental autoimmune encephalomyelitis pathogenesis. [review]
Taken together, our data showed a likely positive feedback mechanism of enhanced IL-6 (zeige IL6 Antikörper) production in ectopic milieu. The high levels of IL-6 (zeige IL6 Antikörper) in the peritoneal cavity stimulate the expression of CCL17 (zeige CCL17 Antikörper) in endometrial stromal cells by activating JNK (zeige MAPK8 Antikörper) signal pathway, and then, CCL17 (zeige CCL17 Antikörper) further induces CCR4 expression on macrophages, which eventually leads to an increase in IL-6 (zeige IL6 Antikörper) production via NF-kappaB (zeige NFKB1 Antikörper) activation.
Investigations showed that the level of CCR4 could be induced by TNF-alpha (zeige TNF Antikörper) dependent of NF-kappaB (zeige NFKB1 Antikörper) activation in CRC (zeige CALR Antikörper) cells. CCR4 might be implicated in TNF-alpha (zeige TNF Antikörper)-regulated cancer cells metastasis.
Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22 (zeige CCL22 Antikörper)-CCR4 signaling axis.
monocyte chemoattractant protein-1 (MCP-1 (zeige CCL2 Antikörper)), an endogenous CCR4-binding ligand, was specifically upregulated in the head and neck squamous cell carcinomamicroenvironment compared to the other four CCR4-binding ligands
Chemokine (zeige CCL1 Antikörper) receptors CCR3 (zeige CCR3 Antikörper) and CCR4, and the mucosa specific chemokine (zeige CCL1 Antikörper) CCL28 (zeige ENC1 Antikörper) have predominant roles in oral wound healing by increasing human gingiva fibroblast proliferation, migration, and the secretion of IL-6 (zeige IL6 Antikörper) and HGF (zeige HGF Antikörper) and reducing the secretion of TIMP-1 (zeige TIMP1 Antikörper).
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer
The percentage of CXCR3 (zeige CXCR3 Antikörper)(+) CD4 (zeige CD4 Antikörper)(+) TEM (zeige CYLD Antikörper) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA (zeige SELPLG Antikörper)(+) CD4 (zeige CD4 Antikörper)(+) TCM cells expressing CCR6 (zeige CCR6 Antikörper)(+) or CCR4(+)CXCR3 (zeige CXCR3 Antikörper)(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.
Case Report: CCR4+ T-cell depletion by mogamulizumab treatment of adult T-cell leukaemia/lymphoma results in CD8 (zeige CD8A Antikörper)-positive T-cell mediated dermatitis.
data demonstrate a mechanistic or developmental role of CCR4 in the regulation of locomotor and exploratory behaviors
CCR4 is critically involved in regional lymph node dendritic cell-Th17 cell interactions that are necessary for Th17 cell-mediated induction of antitumor CD8 (zeige CD8A Antikörper)+ effector T cells in mice bearing B16 melanoma.
CCR4 is involved in immunosuppression after severe sepsis and suggest that CCR4+ Regulatory T Cells negatively modulate the short and long-term immune responses.
CCL22 (zeige CCL22 Antikörper) was localised mainly on the cell surface and or in the cytoplasm. Within sections of omental milky spot micrometastases, CCR4 was recognised on or in gastric cancer cells, constituent cells milky spots, blood cells and blood endothelial cells
CCR4 is involved in regulating negative selection of polyclonal and T cell receptor (TCR) transgenic thymocytes
results show that the IL-4 (zeige IL4 Antikörper)/CCL22 (zeige CCL22 Antikörper)/CCR4 axis is involved in the migration of Tregs to osteolytic lesion sites, and attenuates development of lesions by inhibiting inflammatory migration and the production of proinflammatory and osteoclastogenic mediators
These data have uncovered a novel role of core components of the Ccr4-Not complex as regulators of transition from partial to genuine induced pluripotent stem cells.
that effective engagement of CCR4 by CCL17 (zeige CCL17 Antikörper) involves two distinct binding domains and interaction with both is required for signaling
NF-kappaB (zeige NFKB1 Antikörper) signaling pathway was involved in the asthmatic change induced by CKLF1, among which CCR4 might play a crucial role
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
, C-C chemokine receptor type 4
, chemokine (C-C) receptor 4
, chemokine (C-C motif) receptor 4
, C-C chemokine receptor type 4-like
, c-C chemokine receptor type 4-like
, CC-chemokine receptor 4
, leukocyte-expressed seven-transmembrane-domain receptor
, CC chemokine receptor 4
, C-C chemokine receptor 4