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CRCP encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Zusätzlich bieten wir Ihnen CGRP Receptor Component Antikörper (12) und CGRP Receptor Component Kits (8) und viele weitere Produktgruppen zu diesem Protein an.
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CGRP (zeige CALCA Proteine) can inhibit microglia activation in vivo in EAE. CGRP (zeige CALCA Proteine) and its receptor may represent novel protective factors in EAE.
CGRP-receptor component protein has been found to interact only with calcitonin (zeige CALCA Proteine)-like receptor and represents a novel neuroendocrine regulatory step in calcitonin gene-related peptide (zeige CALCA Proteine) signaling.
The mouse cDNA for calcitonin receptor-like receptor (CRLR (zeige CALCRL Proteine)) was cloned. The signal transduction mechanism through the CGRP (zeige CALCA Proteine) receptor was studied. mCRLR is a 462-amino acid G-protein-coupled heptahelical receptor (zeige AGTR1 Proteine).
data reinforce and clarify our understanding of CGRP (zeige S100A12 Proteine) receptor localization, and provide evidence that antagonist antibodies bind to target sites in the trigeminovascular system of primates that are involved in the pathology of migraine
CGRP (zeige S100A12 Proteine) family of receptors displays both ligand- and RAMP-dependent signaling bias among the Galphas (zeige GNAS Proteine), Galphai, and Galphaq (zeige GNAQ Proteine)/11 pathways.
In this review, the influence of the CGRP (zeige S100A12 Proteine) family peptides in reproduction and pregnancy is explored and discussed.
This study demonstrates the detailed expression of CGRP (zeige S100A12 Proteine) and its receptor components within spinal trigeminal nucleus in the brainstem and in the spinal cord at C1-level
The extracellular protein domains corresponding to residues 23-133 of calcitonin receptor-like receptor (zeige CALCRL Proteine) and residues 26-117 of receptor activity-modifying protein 1 (RAMP1 (zeige RAMP1 Proteine)) are shown to be sufficient for formation of a stable, folded monodisperse complex.
Data describe the role of residues 23-60 of the calcitonin receptor-like receptor (zeige CALCRL Proteine) in binding with interaction sites within the N-terminus of the calcitonin gene-related peptide (zeige CALCA Proteine) receptor.
Expression of CGRP-RCP was detected in CD34 (zeige CD34 Proteine)+ cells and also in some mature granulocyte samples, providing evidence that CGRP-RCP may be regulated independently of RAMP1 (zeige RAMP1 Proteine) and CRLR (zeige CALCRL Proteine) in hematopoietic cells.
human CGRP-RCP is the genuine orthologue of C17. CGRP-RCP was found to functionally replace C17 in Deltarpc17 yeast cells; CGRP-RCP was identified in a purified human Pol III preparation.
inhibition of ACE (zeige ACE Proteine) seems to augment CGRP (zeige S100A12 Proteine) catabolism.
Increased mRNA expression CGRP-RCP in gravid myometrium supports the possibility of involvement of CGRP (zeige S100A12 Proteine) in the control of myometrial contractility.
This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
calcitonin gene-related peptide-receptor component protein
, DNA-directed RNA polymerase III subunit RPC9
, CGRP-receptor component protein
, RNA polymerase III subunit C9