anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) Antikörper

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). Zusätzlich bieten wir Ihnen ALPL Kits (43) und ALPL Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ALPL 249 P05186
ALPL 11647 P09242
ALPL 25586 P08289
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Top anti-ALPL Antikörper auf antikoerper-online.de

Showing 10 out of 223 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Immunohistochemical analysis of paraffin embedded rat tissue sections (small intestine), staining ALPL in cytoplasm, DAB chromogenic reaction Western blot analysis of Hela cell tissue lysis using ALPL antibody 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$313.50
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-Alkaline Phosphatase antibody, IHC(P) IHC(P): Rat Small Intestine Tissue All lanes: Anti ALPL () at 0.5ug/ml Lane 1: Human Placenta Tissue Lysate at 50ug Lane 2:  Whole Cell Lysate at 40ug Lane 3: JURKAT Whole Cell Lysate at 40ug Predicted bind size: 57KD Observed bind size: 57KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Cat Maus Unkonjugiert ICC, FACS, IF, IP Flow Cytometry: Alkaline Phosphatase, Tissue Non-Specific Antibody (TRA-2-49) [ABIN153427] - Analysis using anti-TRA-2-49. 2102Ep cells were stained with anti-TRA-2-49 antibody (Green) or isotype control antibody (grey). 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Maus Ziege Unkonjugiert CyTOF, FACS, ICC, IHC, IP, WB Detection of ALPL in Rat Stem Cells by Flow Cytometry. Alkaline Phosphatase/ALPL in Mouse Embryo. Alkaline Phosphatase/ALPL was detected in immersion fixed frozen sections of mouse embryonic (E13.5) developing vertebra using Goat Anti-Mouse Alkaline Phosphatase/ALPL Antigen Affinity-purified Poly-clonal Antibody. Image courtesy of Paul J. Simmons, Ph.D., Director, Center for Stem Cell Research, The University of Texas Health Science Center at Houston, Houston, Texas, USA. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Maus PE FACS Detection of Alkaline Phosphatase/ALPL in BG01V Human Cells by Flow Cytometry. BG01V human embryonic stem cells were stained with Mouse Anti-Human Alkaline Phosphatase/ALPL PE-conjugated Monoclonal Antibody. 25 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$211.60
Details
Human Maus Allophycocyanin FACS Detection of Alkaline Phosphatase/ALPL in BG01V Human Cells by Flow Cytometry. BG01V human embryonic stem cells were stained with Mouse Anti-Human Alkaline Phosphatase/ALPL APC-conjugated Monoclonal Antibody. 25 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$234.60
Details
Human Maus Biotin FACS, ICC, IHC Alkaline Phosphatase/ALPL in Human Osteoblasts. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$297.85
Details
Human Maus Unkonjugiert CyTOF, FACS, ICC, IHC Alkaline Phosphatase/ALPL in Human Kidney. Alkaline Phosphatase/ALPL was detected in immersion fixed paraffin-embedded sections of human kidney using Mouse Anti-Human Alkaline Phosphatase/ALPL Monoclonal Antibody. Specific staining was localized to cytoplasm in epithelial cells. Alkaline Phosphatase and Oct-3/4 in BG01V Human Stem Cells. Alkaline Phosphatase/ALPL and Oct-3/4 were detected in human BG01V embryonic stem cells using 10 ug/mL Mouse Anti-Human Alkaline Phosphatase/ALPL Monoclonal Antibody. Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for Alkaline Phosphatase/ALPL using the NorthernLightsル 557-conjugated Anti-Mouse IgG Secondary Antibody (pseudo-stained green 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$308.20
Details
Human Maus Unkonjugiert FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of MCF-7 cells using ALPL mouse mAb (green) and negative control (red) . 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details

ALPL Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ALPL Antikörper

  1. Human Polyclonal ALPL Primary Antibody für IHC (p), WB - ABIN3044314 : Feng, Zhu, Zhang, Jia, Cheng, Ding, Zhu et al.: Amelioration of compound 4,4'-diphenylmethane-bis(methyl)carbamate on high mobility group box1-mediated inflammation and oxidant stress responses in human umbilical vein endothelial cells via ... in International immunopharmacology 2013 (PubMed)
    Show all 18 Pubmed References

  2. Human Polyclonal ALPL Primary Antibody für WB - ABIN5518640 : Li, Xia, Tang, Wang, Bei, Zeng: In vitro and in vivo biocompatibility investigation of diamond-like carbon coated nickel-titanium shape memory alloy. in Artificial cells, blood substitutes, and immobilization biotechnology 2011 (PubMed)
    Show all 18 Pubmed References

  3. Rat (Rattus) Polyclonal ALPL Primary Antibody für WB - ABIN5518639 : Xu, Dong, Huang, Li, Qin, Ren, Guo, Chen, Huang: Decreased osteoclastogenesis, osteoblastogenesis and low bone mass in a mouse model of type 2 diabetes. in Molecular medicine reports 2014 (PubMed)
    Show all 18 Pubmed References

  4. Human Monoclonal ALPL Primary Antibody für CyTOF, FACS - ABIN4900675 : Wang, Zhao, Shi, Wei, Halloran, Clark, Jacobs, Kingery: Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. in Bone 2009 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal ALPL Primary Antibody für FACS - ABIN4898136 : Eshel, Sharabi-Nov, Dally: Leukocyte alkaline phosphatase (LAP) by flow cytometry. in MLO: medical laboratory observer 2013 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal ALPL Primary Antibody für FACS - ABIN4898137 : Ramirez, Gerbal-Chaloin, Milhavet, Qiang, Becker, Assou, Lemaître, Hamamah, De Vos: Brief report: benchmarking human pluripotent stem cell markers during differentiation into the three germ layers unveils a striking heterogeneity: all markers are not equal. in Stem cells (Dayton, Ohio) 2011 (PubMed)
    Show all 3 Pubmed References

  7. Human Monoclonal ALPL Primary Antibody für FACS, IHC - ABIN969500 : Kannampuzha, Tupy, Pritzker: Mercaptopyruvate inhibits tissue-nonspecific alkaline phosphatase and calcium pyrophosphate dihydrate crystal dissolution. in The Journal of rheumatology 2009 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal ALPL Primary Antibody für FACS, ICC - ABIN4900651 : Pytlík, Stehlík, Soukup, Kalbácová, Rypácek, Trc, Mulinková, Michnová, Kideryová, Zivný, Klener, Veselá, Trnený, Klener: The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering. in Biomaterials 2009 (PubMed)
    Show all 2 Pubmed References

  9. Cat (Feline) Monoclonal ALPL Primary Antibody für ICC, FACS - ABIN153427 : Chou, Gu, Gao, Dowey, Wang, Shi, Li, Ye, Cheng, Cheng: A facile method to establish human induced pluripotent stem cells from adult blood cells under feeder-free and xeno-free culture conditions: a clinically compliant approach. in Stem cells translational medicine 2015 (PubMed)

  10. Human Monoclonal ALPL Primary Antibody für FACS, IF - ABIN5572435 : Moss: Diagnostic aspects of alkaline phosphatase and its isoenzymes. in Clinical biochemistry 1988 (PubMed)

Weitere Antikörper gegen ALPL Interaktionspartner

Human Alkaline Phosphatase, Liver/bone/kidney (ALPL) Interaktionspartner

  1. These results show that an increase of TNAP activity in ACDC (arterial calcification due to deficiency of CD73) contributes to ectopic calcification by disrupting the extracellular balance of PPi and Pi and identify potential therapeutic targets for ACDC.

  2. the identification of 11 novel ALPL mutations in the five different HPP (zeige SPTA1 Antikörper) forms and the observation of a recurrent mutation, p. (Thr166Ile) in the Spanish population expand our knowledge of pathogenic ALPL mutations.

  3. Preoperative calcitonin (zeige CALCA Antikörper) levels were correlated with the presence of tumor, whereas alkaline phosphatase (ALP) levels were not. There were no significant associations between tumor volume and ALP (zeige ALP Antikörper) or calcitonin (zeige CALCA Antikörper) levels in the preoperative or postoperative periods. During long-term follow-up, serum ALP (zeige ALP Antikörper) was significantly associated with tumor recurrence, but serum calcitonin (zeige CALCA Antikörper) was not.

  4. His ALPL gene mutation came from c.228delG mutation in his mother and c.407G>A compound heterozygous mutation in his father

  5. Both PPARgamma (zeige PPARG Antikörper) gene expression and TNALP activity increased during intracellular lipid accumulation in HepG2 and 3T3-L1 cells. Inhibition of TNALP blocked intracellular lipid accumulation but did not alter expression of the PPARgamma (zeige PPARG Antikörper) gene.

  6. ALPL is a major contributor to the pathogenesis of Prostate cancer progression.

  7. ALPL expression is significantly upregulated in human masticatory mucosa during wound healing

  8. serum ALP (zeige ALP Antikörper) levels were not associated with increased death risk in prevalent HD patients over a 5-year interval.

  9. In conclusion, serum levels of BSP, ALP, ICTP, and PSA increased in patients with bone metastases, and combined detection of all markers could improve the positive-predictive value.

  10. results reveal that the amino acid substitutions at position 426 of TNSALP differentially affect the structure and function of TNSALP, leading to understanding of the molecular and cellular basis of hypophosphatasia.

Mouse (Murine) Alkaline Phosphatase, Liver/bone/kidney (ALPL) Interaktionspartner

  1. The results are the first to demonstrate a role for ENC1 (zeige ENC1 Antikörper) in the control of osteoblast differentiation. Additionally, the contrasting mineralization phenotypes and transcriptional patterns seen with coordinate knockdown of both ENC1 (zeige ENC1 Antikörper) isoforms vs selective knockdown of 67 kDa ENC1 (zeige ENC1 Antikörper) suggest opposing roles for the isoforms in regulation of osteoblastic differentiation, through effects on Alpl expression and phosphate cellular

  2. TNAP overexpression in vascular endothelium in mice leads to an unusual course of coronary atherosclerosis and was accompanied by the reduction in body weight and left ventricular ejection fraction.

  3. Data, including data from studies using cells from transgenic/knockout mice, suggest that Med1 (zeige MBD4 Antikörper) plays role in enamel formation; Med1 (zeige MBD4 Antikörper) induces Alpl via stimulation of Notch1 (zeige NOTCH1 Antikörper) signaling by forming Notch1 (zeige NOTCH1 Antikörper)-RBP-Jk (zeige RBPJ Antikörper) complex on Alpl promoter. (Med1 (zeige MBD4 Antikörper) = mediator complex subunit 1 (zeige MED1 Antikörper); Alpl = alkaline phosphatase, liver-bone-kidney; Notch1 (zeige NOTCH1 Antikörper) = Notch gene homolog 1 (zeige NOTCH1 Antikörper); RBP-Jk (zeige RBPJ Antikörper) = kappa J region recombining binding protein suppressor of hairless (zeige RBPJ Antikörper))

  4. These analyses revealed that TNAP deficient mice present an increased proliferation of neural precursors, an altered neuronal morphology, and an augmented neuronal activity. We found that these alterations were associated with a partial downregulation of the purinergic P2X7 receptor (P2X7R (zeige P2RX7 Antikörper)).

  5. Despite similar deficiencies in alkaline phosphatase, Alpl(-/-) mice develop craniosynostosis and a brachycephalic/acrocephalic craniofacial shape of variable penetrance.

  6. Prevention of lethal murine hypophosphatasia by neonatal ex vivo gene therapy using lentivirally transduced bone marrow cells expressing Akp-2.

  7. TNAP in the vasculature contributes to the pathology of medial vascular calcification and that it is a druggable target.

  8. In cardiac fibroblasts, TNAP expression and activity is induced by sFRP2 (zeige SFRP2 Antikörper).

  9. p107 (zeige RBL1 Antikörper) is required for the efficient recruitment of an activating SWI (zeige SMARCA1 Antikörper)/SNF (zeige SNRPA Antikörper) chromatin-remodeling complex, an essential event in Alpl induction.

  10. Inhibition of rhBMP-2-induced ALP (zeige CCL21A Antikörper) activity by intracellular delivery of SMURF1 (zeige SMURF1 Antikörper) in murine calvarial preosteoblast cells.

Cow (Bovine) Alkaline Phosphatase, Liver/bone/kidney (ALPL) Interaktionspartner

  1. The peri (zeige PLIN1 Antikörper)-partum characteristics of serum bone-specific alkaline phosphatase (BAP (zeige PHB2 Antikörper)) and urinary deoxypyridinoline (DPD (zeige DPYD Antikörper)) in dairy cattle are reported.

  2. GPI (zeige GPI Antikörper)-anchored proteins are localized on the outer layer of plasma membranes and clustered in microdomains generally called lipid rafts.

ALPL Antigen-Profil

Protein Überblick

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.

Genbezeichner und Symbole assoziert mit ALPL

  • alkaline phosphatase, liver/bone/kidney L homeolog (alpl.L) Antikörper
  • alkaline phosphatase, liver/bone/kidney (ALPL) Antikörper
  • alkaline phosphatase, intestinal, gene 2 (alpi.2) Antikörper
  • alkaline phosphatase, liver/bone/kidney pseudogene (LOC100031702) Antikörper
  • alkaline phosphatase, liver/bone/kidney (Alpl) Antikörper
  • Akp-2 Antikörper
  • Akp2 Antikörper
  • ALP Antikörper
  • alpl Antikörper
  • AP-TNAP Antikörper
  • APTNAP Antikörper
  • HOPS Antikörper
  • iap Antikörper
  • PHOA Antikörper
  • TNAP Antikörper
  • TNS-AP Antikörper
  • TNSALP Antikörper

Bezeichner auf Proteinebene für ALPL

tissue-nonspecific alkaline phosphatase , alkaline phosphatase, tissue-nonspecific isozyme , tissue non-specific alkaline phosphatase , alkaline phosphatase, liver/bone/kidney , alkaline phosphatase, tissue-nonspecific isozyme-like , alkaline phosphatase liver/bone/kidney isozyme , alkaline phosphomonoesterase , glycerophosphatase , liver/bone/kidney-type alkaline phosphatase , tissue-nonspecific ALP , alkaline phosphatase 2, liver , AP-TNAP , TNSALP , Tissue-nonspecific ALP alkaline phosphatase , alkaline phosphatase tissue non-specific isoform , liver/bone/kidney isozyme

GENE ID SPEZIES
380589 Xenopus laevis
403548 Canis lupus familiaris
717809 Macaca mulatta
100144722 Xenopus (Silurana) tropicalis
100401643 Callithrix jacchus
100440770 Pongo abelii
100031702 Monodelphis domestica
456600 Pan troglodytes
100602436 Nomascus leucogenys
249 Homo sapiens
11647 Mus musculus
25586 Rattus norvegicus
280994 Bos taurus
100170147 Sus scrofa
727689 Felis catus
396317 Gallus gallus
101123195 Ovis aries
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