anti-Human EPH Receptor A4 Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended EPH Receptor A4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
EPH Receptor A4 (EPHA4) Antikörper
  • ephe
  • EPHA4
  • Ci-Eph1
  • sek
  • hek8
  • rtk1
  • tyr01
  • 2900005C20Rik
  • AI385584
  • Cek8
  • Hek8
  • Sek
  • Sek1
  • Tyro1
  • rb
  • HEK8
  • SEK
  • TYRO1
  • RGD1560587
  • EPH receptor A4
  • ephrin receptor epsilon
  • Eph receptor A4
  • EPHA4
  • ephe
  • epha4
  • Epha4
Epitop
AA 570-620
30
21
20
14
13
12
11
10
7
5
4
4
4
3
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Ratte (Rattus)
157
73
36
10
10
10
7
7
7
6
4
4
2
2
2
2
2
1
1
1
Wirt
Kaninchen
150
23
17
2
Klonalität
Polyklonal
Konjugat
Dieser EPH Receptor A4 Antikörper ist unkonjugiert
9
8
8
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
133
85
85
50
19
17
12
7
4
2
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN734123
$ 295.90
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2812839 IF (p) Alexa Fluor 594 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN734129 IF (p) Cy7 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN734128 IF (p) Cy5.5 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN734127 IF (p) Cy5 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN734130 IF (p) FITC Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN734126 IF (p) Cy3 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN895463 IF (p) Alexa Fluor 647 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN895466 IF (p) Alexa Fluor 350 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN895462 IF (p) Alexa Fluor 488 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN895465 IF (p) Alexa Fluor 555 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN5002005 IF (p) Alexa Fluor 750 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal
1 ABIN5002004 IF (p) Alexa Fluor 680 Rabbit IgG AA 570-620 Anmelden zum Anzeigen Polyclonal

General

Antigen EPH Receptor A4 (EPHA4) Antikörper
Epitop AA 570-620
(30), (21), (20), (14), (13), (12), (11), (10), (7), (5), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Ratte (Rattus)
(157), (73), (36), (10), (10), (10), (7), (7), (7), (6), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(150), (23), (17), (2)
Klonalität
Polyklonal
Konjugat Dieser EPH Receptor A4 Antikörper ist unkonjugiert
(9), (8), (8), (6), (6), (6), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(133), (85), (85), (50), (19), (17), (12), (7), (4), (2), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-EPH Receptor A4 Antikörper

Target Details EPH Receptor A4 Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human EphA4
Isotyp IgG

Target Details EPH Receptor A4

Produktdetails anti-EPH Receptor A4 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Eph Receptor A4 (EPHA4 Antibody Abstract)
Hintergrund

Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.

Subcellular location: Cytoplasm

Synonyms: SEK, HEK8, TYRO1, Ephrin type-A receptor 4, EPH-like kinase 8, EK8, Tyrosine-protein kinase TYRO1, Tyrosine-protein kinase receptor SEK, EPHA4

Gen-ID 2043
UniProt P54764
Pathways RTK Signalweg

Anwendungsinformationen

Produktdetails anti-EPH Receptor A4 Antikörper Target Details EPH Receptor A4 Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-EPH Receptor A4 Antikörper Target Details EPH Receptor A4 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails anti-EPH Receptor A4 Antikörper Target Details EPH Receptor A4 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-EPH Receptor A4 (EPHA4) (AA 570-620) antibody (ABIN734123) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti EP...
Immunohistochemistry (IHC) image for anti-EPH Receptor A4 (EPHA4) (AA 570-620) antibody (ABIN734123) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti EPH receptor ...