EPH Receptor A4 Antikörper (AA 777-986)

Produktnummer ABIN1724712

Zitiert in 3+ Publikationen. Der Maus Monoklonal anti-EPH Receptor A4 Antikörper (Klon 7D3D4) (ABIN1724712) detektiert spezifisch EPH Receptor A4 in ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für EPH Receptor A4 Antikörper (AA 777-986) (ABIN1724712)

Target: EPH Receptor A4 (EPHA4)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor A4 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 7D3D4

Produktdetails anti-EPH Receptor A4 Antikörper

Bindungsspezifität: AA 777-986

Verwendungszweck: EphA4 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of EphA4 (aa777-986) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-EPH Receptor A4 Antikörper (ABIN1724712)

Takemoto, Fukuda, Sonoda, Murakami, Tanaka, Yamamoto: "Ephrin-B3-EphA4 interactions regulate the growth of specific thalamocortical axon populations in vitro." in: The European journal of neuroscience, Vol. 16, Issue 6, pp. 1168-72, (2002) (PubMed).

Walkenhorst, Dütting, Handwerker, Huai, Tanaka, Drescher: "The EphA4 receptor tyrosine kinase is necessary for the guidance of nasal retinal ganglion cell axons in vitro." in: Molecular and cellular neurosciences, Vol. 16, Issue 4, pp. 365-75, (2001) (PubMed).

Wilkinson: "Multiple roles of EPH receptors and ephrins in neural development." in: Nature reviews. Neuroscience, Vol. 2, Issue 3, pp. 155-64, (2001) (PubMed).

Details zu EPH Receptor A4

Target: EPH Receptor A4 (EPHA4)

Andere Bezeichnung: EphA4

Hintergrund: EphA4: EPH receptor A4. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

UniProt: P54764

Pathways: RTK Signalweg