anti-Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antikörper

Bezeichnung:
anti-Amyloid beta (A4) Precursor-Like Protein 2 Antikörper (APLP2)
Auf www.antikoerper-online.de finden Sie aktuell 95 Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Amyloid beta (A4) Precursor-Like Protein 2 Proteine (10) und Amyloid beta (A4) Precursor-Like Protein 2 Kits (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 121 Amyloid beta (A4) Precursor-Like Protein 2 Produkte verfügbar.
Synonyme:
AI790698, APLP-2, APLP2, aplp2 A, aplp2 B, Apph, APPL2, CDEBP, MGC86389, si:dkey-11k4.3, WALPLP2
Alle Antikörper anzeigen Gen GeneID UniProt
APLP2 334 Q06481
APLP2 11804 Q06335
APLP2 64312  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Human Antikörper:

anti-Mouse (Murine) Antikörper:

anti-Rat (Rattus) Antikörper:

Alle verfügbaren anti-Amyloid beta (A4) Precursor-Like Protein 2 Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Am meisten referenzierte anti-Amyloid beta (A4) Precursor-Like Protein 2 Antikörper

  1. Human Polyclonal APLP2 Primary Antibody für EIA, WB - ABIN950473 : Tuli, Sharma, Capek, Naslavsky, Caplan, Solheim: Mechanism for amyloid precursor-like protein 2 enhancement of major histocompatibility complex class I molecule degradation. in The Journal of biological chemistry 2009 (PubMed)
    Zeige alle 5 Referenzen für 950473

  2. Human Polyclonal APLP2 Primary Antibody für IHC (p), WB - ABIN658567 : Tuli, Sharma, McIlhaney, Talmadge, Naslavsky, Caplan, Solheim: Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-K(d) MHC class I molecule. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Zeige alle 3 Referenzen für 658567

  3. Human Polyclonal APLP2 Primary Antibody für ELISA, WB - ABIN1450689 : Sprecher, Grant, Grimm, OHara, Norris, Norris, Foster: Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family. in Biochemistry 1993 (PubMed)

  4. Human Polyclonal APLP2 Primary Antibody für ICC, IF - ABIN4281104 : Jackson, Du, Janesko-Feldman, Vagni, Dezfulian, Poloyac, Jackson, Clark, Kochanek: The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2015 (PubMed)

Weitere Antikörper gegen Amyloid beta (A4) Precursor-Like Protein 2 Interaktionspartner

Zebrafish Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Interaktionspartner

  1. these results indicate the Appa (zeige APP Antikörper)-RFP (zeige MKRN1 Antikörper) and Aplp2 fusion proteins are likely secreted from the central nervous system and accumulate in the embryonic veins independent of blood flow.

Human Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Interaktionspartner

  1. This paper demonstrates an important role for APLP2 in refractive development in mice and humans, suggesting a high level of evolutionary conservation of the signaling pathways underlying refractive eye development.

  2. Data show that amyloid precursor-like protein 2 (APLP2) expression is elevated in pancreatic cancer metastases.

  3. We conclude that PCSK9 (zeige PCSK9 Antikörper) enhances the degradation of the LDLR (zeige LDLR Antikörper) independently of either APLP2 or sortilin (zeige SORT1 Antikörper) both ex vivo and in mice.

  4. APLP1 (zeige APLP1 Antikörper) and APLP2, behave similarly to APP (zeige APP Antikörper) in that they both associate with assembled NMDA receptors in the endoplasmic reticulum

  5. our discoveries establish a role for APLP2 in the growth of pancreatic cancer cells and show that inhibitors preventing APLP2 cleavage reduce the viability of pancreatic cancer cells.

  6. amyloid precursor protein-like (zeige APP Antikörper) protein-2, but not amyloid precursor protein (zeige APP Antikörper), is involved in mediating postendocytic delivery of PCSK9 (zeige PCSK9 Antikörper) to lysosomes and is therefore important for PCSK9 (zeige PCSK9 Antikörper) function

  7. Aberrant enhancement of YWK-II/APLP2 by nuclear export of Bat3 (zeige BAT3 Antikörper) may play a role in cancer development by inhibiting cell apoptosis.

  8. APP (zeige APP Antikörper) and its mammalian homologs, amyloid precursor-like proteins APLP1 (zeige APLP1 Antikörper) and APLP2, participate under physiological conditions via trans-cellular dimerization in synaptogenesis.

  9. APLP-2 (and APLP1 (zeige APLP1 Antikörper)) are capable of activating gene transcription via binding to Mint3 (zeige APBA3 Antikörper).

  10. Regulation of major histocompatibility complex class I molecule expression on cancer cells by amyloid precursor-like protein 2.

Mouse (Murine) Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Interaktionspartner

  1. These data support the notion that APP (zeige APP Antikörper) and APLP2 facilitate transmitter release, likely through the interaction with the neurotransmitter release machinery.

  2. This paper demonstrates an important role for APLP2 in refractive development in mice and humans, suggesting a high level of evolutionary conservation of the signaling pathways underlying refractive eye development.

  3. Study provides compelling evidence for an essential role of both APP (zeige APP Antikörper) and APLP2 for neuronal and synaptic morphology as well as hippocampal function and suggest an acute and specific function of endogenous APPsalpha to facilitate synaptic plasticity

  4. The study investigates the subcellular distribution patterns of the metal ions Cu, Zn, Fe, and Ca in individual neurons derived from APP (zeige APP Antikörper) and APLP2 knockout mice brains to further define their role in metal homeostasis.

  5. This study further highlights the distinct and essential role of APLP2 at NMJ synapses that cannot be compensated by APP (zeige APP Antikörper).

  6. Amyloid precursor protein (APP)/APP-like (zeige APP Antikörper) protein 2 (APLP2) expression is required to initiate endosome-nucleus-autophagosome

  7. The study investigated copper, iron, zinc and manganese levels in APP (zeige APP Antikörper) and APLP-2 single knockout mice as well as homozygous:hemizygous knockout mice at 3, 12 and 18 plus months of age.

  8. Data reveal that APLP2 is specifically required for proper cell cycle exit of neuronal progenitors, and thus has a distinct role in priming cortical progenitors for neuronal differentiation.

  9. APLP2 and the intracellular domain of APP (zeige APP Antikörper) are not essential for coherent activity patterns in the hippocampus, but have subtle effects on synaptic plasticity and fine-tuning of network oscillations.

  10. Gain and loss of function experiments demonstrate that miR (zeige MLXIP Antikörper)-153 suppresses expression of amyloid precursor protein (APP (zeige APP Antikörper)) and APLP2.

Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antigen-Profil

Beschreibung des Gens

This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with Amyloid beta (A4) Precursor-Like Protein 2 (APLP2)

  • amyloid beta (A4) precursor-like protein 2 (aplp2-b) Antikörper
  • amyloid beta (A4) precursor-like protein 2 (APLP2) Antikörper
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (APPL2) Antikörper
  • amyloid beta (A4) precursor-like protein 2 (aplp2) Antikörper
  • amyloid beta (A4) precursor-like protein 2 (Aplp2) Antikörper
  • AI790698 Antikörper
  • APLP-2 Antikörper
  • APLP2 Antikörper
  • aplp2 A Antikörper
  • aplp2 B Antikörper
  • Apph Antikörper
  • APPL2 Antikörper
  • CDEBP Antikörper
  • MGC86389 Antikörper
  • si:dkey-11k4.3 Antikörper
  • WALPLP2 Antikörper

Bezeichner auf Proteinebene für APLP2

amyloid beta (A4) precursor-like protein 2 , amyloid-beta-like protein B , DIP13 beta , adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 , suppression of tumorigenicity 14 , amyloid-like protein 2 , DCC-interacting protein 13-beta-like , amyloid-like protein 2-like , amyloid-beta-like protein A , CDEI box-binding protein , amyloid precursor protein homolog HSD-2 , CDEBP , Amyloid protein precursor-like protein 2 , amyloid beta (A4) precursor-like protein 2-like , sperm membrane protein (YWK-II) , sperm membrane protein YWK-II

GENE ID SPEZIES
431789 Xenopus laevis
452197 Pan troglodytes
479393 Canis lupus familiaris
481297 Canis lupus familiaris
718819 Macaca mulatta
741867 Pan troglodytes
785005 Bos taurus
796801 Danio rerio
100068170 Equus caballus
100072668 Equus caballus
100076773 Ornithorhynchus anatinus
100126835 Sus scrofa
100358231 Oryctolagus cuniculus
100380132 Xenopus (Silurana) tropicalis
100404192 Callithrix jacchus
100414190 Callithrix jacchus
100470064 Ailuropoda melanoleuca
100477041 Ailuropoda melanoleuca
431790 Xenopus laevis
100557178 Anolis carolinensis
334 Homo sapiens
11804 Mus musculus
64312 Rattus norvegicus
419727 Gallus gallus
100190991 Sus scrofa
Ausgewählte Anbieter für anti-Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antikörper
Haben Sie etwas anderes gesucht?