APLP2 Antikörper (C-Term)

Produktnummer ABIN950473

Produktdetails anti-APLP2 Antikörper

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Bindungsspezifität: AA 592-621, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APLP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to APPL2.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 592-621 amino acids from the C-terminal region of human APLP2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-APLP2 Antikörper (ABIN950473)

Tuli, Sharma, McIlhaney, Talmadge, Naslavsky, Caplan, Solheim: "Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-K(d) MHC class I molecule." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 1978-87, (2008) (PubMed).

Details zu APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Andere Bezeichnung: APPL2 / APLP2 (APLP2 Produkte)

Synonyme: HAI antikoerper, MT-SP1 antikoerper, MTSP1 antikoerper, PRSS14 antikoerper, SNC19 antikoerper, TADG15 antikoerper, TMPRSS14 antikoerper, APLP-2 antikoerper, APPH antikoerper, APPL2 antikoerper, CDEBP antikoerper, AI790698 antikoerper, Apph antikoerper, WALPLP2 antikoerper, aplp2 B antikoerper, APLP2 antikoerper, si:dkey-11k4.3 antikoerper, aplp2 A antikoerper, MGC86389 antikoerper, suppression of tumorigenicity 14 antikoerper, amyloid beta precursor like protein 2 antikoerper, amyloid beta (A4) precursor-like protein 2 antikoerper, amyloid beta (A4) precursor-like protein 2 S homeolog antikoerper, amyloid beta (A4) precursor-like protein 2 L homeolog antikoerper, ST14 antikoerper, APLP2 antikoerper, Aplp2 antikoerper, aplp2.S antikoerper, aplp2 antikoerper, aplp2.L antikoerper

Hintergrund: APLP2 may play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.Synonyms: APPH, Amyloid protein homolog, Amyloid-like protein 2, CDEBP, CDEI box-binding protein

Gen-ID: 334

NCBI Accession: NP_001135748

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour