STAT3 Antikörper (Middle Region)
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- Target Alle STAT3 Antikörper anzeigen
- STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schwein, Hund, Pferd, Schaf, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STAT3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- FGKYCRPESQ EHPEADPGSA APYLKTKFIC VTPTTCSNTI DLPMSPRTLD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against STAT3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human STAT3
- Top Product
- Discover our top product STAT3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 770 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits." in: Virology, Vol. 494, pp. 1-14, (2016) (PubMed).
: "
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Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits." in: Virology, Vol. 494, pp. 1-14, (2016) (PubMed).
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- Target
- STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
- Andere Bezeichnung
- STAT3 (STAT3 Produkte)
- Synonyme
- 1110034C02Rik antikoerper, AW109958 antikoerper, Aprf antikoerper, APRF antikoerper, HIES antikoerper, Xstat3 antikoerper, aprf antikoerper, hies antikoerper, stat3 antikoerper, wu:fc15d02 antikoerper, wu:fl59g06 antikoerper, z-Stat3 antikoerper, signal transducer and activator of transcription 3 antikoerper, signal transduction and activation of transcription 3 antikoerper, signal transducer and activator of transcription 3, gene 1 L homeolog antikoerper, signal transducer and activator of transcription 3 (acute-phase response factor) antikoerper, STAT3 antikoerper, stat3 antikoerper, Stat3 antikoerper, stat3.1.L antikoerper
- Hintergrund
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STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act a
Alias Symbols: APRF, FLJ20882, MGC16063, HIES
Protein Interaction Partner: MTOR, GADD45A, BMX, BLK, UBC, SYK, LMO2, SRI, HIC1, GNB2, USP22, RELA, COPS5, BRD4, ADRB2, PSMG3, TBCD, TBC1D15, PUS7, LUC7L2, ARFIP1, IVNS1ABP, MSH2, BMH1, SIN3A, EGFR, PIAS3, HDAC3, SRC, LYN, JAK3, JAK2, HES5, TRIM28, HES1, HCK, FYN, FGR, HNRNPM, SULT2A
Protein Size: 770 - Molekulargewicht
- 88 kDa
- Gen-ID
- 6774
- NCBI Accession
- NM_139276, NP_644805
- UniProt
- P40763
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Neurotrophin Signalübertragung, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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