STAT3 Produkte
(Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
Kategorien
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte STAT3 Kategorien
STAT3 Antikörper
High quality antibodies with extensive validation data.
STAT3 ELISA Kits
Reliable ELISA kits for a wide range of species.
STAT3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene STAT3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (1)
- (8)
- (1)
Kat. Nr.
ABIN2855865
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA, IF, ICC
Validierungen
- (3)
- (7)
Kat. Nr.
ABIN6265317
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA, IP, IF, ICC
Validierungen
- (3)
- (9)
Kat. Nr.
ABIN6256411
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene STAT3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validierungen
- (3)
- (6)
Kat. Nr.
ABIN1981839
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN625245
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN1981729
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene STAT3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN1321594
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125094
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321596
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren STAT3 Produkten
: "Tibetan medicine Ershiwuwei Lvxue Pill attenuates collagen-induced arthritis via inhibition of JAK2/STAT3 signaling pathway." in: Journal of ethnopharmacology, Vol. 270, pp. 113820, (2021) (PubMed).: "Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin." in: International journal of pharmaceutics, Vol. 606, pp. 120872, (2021) (PubMed).
: "Bazedoxifene Plays a Protective Role against Inflammatory Injury of Endothelial Cells by Targeting CD40." in: Cardiovascular therapeutics, Vol. 2020, pp. 1795853, (2021) (PubMed).
: "Oleacein and Foam Cell Formation in Human Monocyte-Derived Macrophages: A Potential Strategy Against Early and Advanced Atherosclerotic Lesions." in: Pharmaceuticals (Basel, Switzerland), Vol. 13, Issue 4, (2020) (PubMed).
: "Serum ERK1/2 proteins fluctuating with HBV infection report frequency of viral-specific CD8+ T cells and predict IFNα therapeutic effect in chronic hepatitis B patients." in: Clinical immunology (Orlando, Fla.), Vol. 219, pp. 108570, (2020) (PubMed).
: "CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling." in: Cell death & disease, Vol. 11, Issue 4, pp. 234, (2020) (PubMed).
: "Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level." in: Life sciences, Vol. 259, pp. 118397, (2020) (PubMed).
: "Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p ..." in: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 62, (2019) (PubMed).
: "Opa interacting protein 5 promotes metastasis of nasopharyngeal carcinoma cells by promoting EMT via modulation of JAK2/STAT3 signal." in: European review for medical and pharmacological sciences, Vol. 23, Issue 2, pp. 613-621, (2019) (PubMed).
: "STAT3, STAT5A, STAT5B and STAT6 proteins are overexpressed in human basal cell carcinoma." in: Clinical and experimental dermatology, (2019) (PubMed).
Synonyme und alternative Namen zu STAT3
signal transducer and activator of transcription 3 (STAT3), signal transduction and activation of transcription 3 (stat3), signal transducer and activator of transcription 3 (stat3), signal transducer and activator of transcription 3 (Stat3), signal transducer and activator of transcription 3, gene 1 L homeolog (stat3.1.L), signal transducer and activator of transcription 3 (acute-phase response factor) (stat3), 1110034C02Rik, Aprf, APRF, aprf, AW109958, HIES, hies, stat3, wu:fc15d02, wu:fl59g06, Xstat3, z-Stat3Bezeichner auf Proteinebene für STAT3
- signal transducer and activator of transcription 3 (acute-phase response factor)
- signal transducer and activator of transcription 3
- signal transduction and activation of transcription 3
- Signal transducer and activator of transcription 3
- signal transducer and activator of transcription 3-like
- acute phase response factor
- acute-phase response factor
- DNA-binding protein APRF
- Protein Stat3
- signal transducer and activator of transcription 3.1
- stat 3
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