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STAT5A Produkte

(Signal Transducer and Activator of Transcription 5A (STAT5A))

Kategorien

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008].

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Ausgewählte STAT5A Kategorien

STAT5A Antikörper

High quality antibodies with extensive validation data.

STAT5A ELISA Kits

Reliable ELISA kits for a wide range of species.

STAT5A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene STAT5A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p), IF (cc)
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN5557532
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, FACS, ICC
Validierungen
  • (2)
  • (7)
Kat. Nr. ABIN1098129
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (6)
Kat. Nr. ABIN950127
Menge 50 μg
Datenblatt Datenblatt

Empfohlene STAT5A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Semi-Quantitative Cell ELISA
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN1981843
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN1981730
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6959477
Menge 96 tests
Datenblatt Datenblatt

Empfohlene STAT5A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321600
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321602
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3134027
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren STAT5A Produkten

Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Sławińska, Lakomy, Biernat, Sokołowska-Wojdyło, Karczewska, Zabłotna, Jankau, Nowicki, Sobjanek: "STAT3, STAT5A, STAT5B and STAT6 proteins are overexpressed in human basal cell carcinoma." in: Clinical and experimental dermatology, (2019) (PubMed).

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Shen, Li, You, Wu, Wu, Zhao, Zhu, Guo, Li, Li, Ma, Yang, Chen: "Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 99, pp. 60-69, (2017) (PubMed).

Kobayashi, Watanabe, Suzuki, Furu, Ito, Ito, Matsuda, Yoshitomi: "TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells." in: European journal of immunology, Vol. 46, Issue 2, pp. 360-71, (2016) (PubMed).

Pastuszak-Lewandoska, Doma?ska, Czarnecka, Kordiak, Migdalska-S?k, Nawrot, Kisza?kiewicz, Antczak, Górski, Brzezia?ska: "Expression of STAT5, COX-2 and PIAS3 in correlation with NSCLC histhopathological features." in: PLoS ONE, Vol. 9, Issue 8, pp. e104265, (2014) (PubMed).

Hu, Zhang, Tang, Su, Li, Chen, Zhang, Cai, Zhu: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." in: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).

Correale, Farez, Ysrraelit: "Role of prolactin in B cell regulation in multiple sclerosis." in: Journal of neuroimmunology, Vol. 269, Issue 1-2, pp. 76-86, (2014) (PubMed).

Yang, Sun, Sun, Qi: "Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte." in: Molecular biology reports, Vol. 39, Issue 9, pp. 9113-22, (2012) (PubMed).

Drechsler, Grötzinger, Hermanns: "Characterization of the rat oncostatin M receptor complex which resembles the human, but differs from the murine cytokine receptor." in: PLoS ONE, Vol. 7, Issue 8, pp. e43155, (2012) (PubMed).

Synonyme und alternative Namen zu STAT5A

signal transducer and activator of transcription 5A (STAT5A), signal transducer and activator of transcription 5A (Stat5a), signal transducer and activator of transcription 5a (stat5a), signal transducer and activator of transcription 5A (LOC100348518), signal transducer and activator of transcription 5A (LOC100716811), AA959963, MGF, STAT5, Stat5, stat5, STAT5A, STAT5A/MGF, stat5b, STATA5

Bezeichner auf Proteinebene für STAT5A

  • mammary gland factor STAT5A
  • mammary gland factor
  • signal transducer and activator of transcription 5
  • STAT5A, Mammary Gland Factor
  • signal transducer and activator of transcription 5A
  • signal transducer and activator of transcription 5A-like
  • signal transducer and activator of transcription 5B
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